N1-Methylpseudouridine-5′-triphosphate tetralithium (Synonyms: 1-Methylpseudouridine-5′-triphosphate tetralithium)

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N1-Methylpseudouridine-5′-triphosphate (1-Methylpseudouridine-5′-triphosphate) tetralithium is a nucleobase-modified nucleotide, used for synthesizing mRNA with reduced immunogenicity and improved stability.

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N1-Methylpseudouridine-5′-triphosphate tetralithium Chemical Structure

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Other In-stock Forms of N1-Methylpseudouridine-5′-triphosphate tetralithium:

N1-Methylpseudouridine-5′-triphosphate trisodium

Other Forms of N1-Methylpseudouridine-5′-triphosphate tetralithium:

N1-Methylpseudouridine-5′-triphosphate trisodium In-stock
N1-Methylpseudouridine-5′-triphosphate Get quote

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Description	N1-Methylpseudouridine-5′-triphosphate (1-Methylpseudouridine-5′-triphosphate) tetralithium is a nucleobase-modified nucleotide, used for synthesizing mRNA with reduced immunogenicity and improved stability^[1].
Molecular Weight	521.90
Formula	C₁₀H₁₃Li₄N₂O₁₅P₃
SMILES	O[C@H]1[C@@H](O)[C@H](C(C(N2)=O)=CN(C)C2=O)O[C@@H]1COP(OP(OP(O[Li])(O[Li])=O)(O[Li])=O)(O[Li])=O
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (270 KB) Handling Instructions (2659 KB)
References	[1]. Andries O, Mc Cafferty S, De Smedt SC, Weiss R, Sanders NN, Kitada T. N(1)-methylpseudouridine-incorporated mRNA outperforms pseudouridine-incorporated mRNA by providing enhanced protein expression and reduced immunogenicity in mammalian cell lines and mice. J Control Release. 2015;217:337-344. [Content Brief]

N1-Methylpseudouridine-5′-triphosphate tetralithium Related Classifications

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

N1-Methylpseudouridine-5′-triphosphate tetralithium1-Methylpseudouridine-5′-triphosphate tetralithiumDNA/RNA SynthesisNucleoside Antimetabolite/Analognucleobase-modified nucleotidemRNAInhibitorinhibitorinhibit

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N1-Methylpseudouridine-5′-triphosphate tetralithium (Synonyms: 1-Methylpseudouridine-5′-triphosphate tetralithium)

Other Forms of N1-Methylpseudouridine-5′-triphosphate tetralithium:

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