Propionyl-DL-carnitine chloride

Name: Propionyl-DL-carnitine chloride
Brand: MedChemExpress
SKU: HY-101018
Rating: 4.5 (0 reviews)

製品番号: HY-101018 純度: 98.10%: Data Sheet SDS COA 取扱説明書
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Propionyl-DL-carnitine chloride is a carnitine derivative. Propionyl-DL-carnitine chloride can be used for the research of inflammation.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

Propionyl-DL-carnitine chloride 構造式

CAS 番号 : 18828-58-5

容量	価格（税別）	在庫状況	数量

>無料サンプル (0.1 - 0.2 mg)		今すぐ申し込む
>無料サンプル (0.1 - 0.2 mg)		今すぐ申し込む
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	USD 35	在庫あり	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	USD 35	在庫あり	Estimated Time of Arrival: December 31
Solid
5 mg	$32	在庫あり	Estimated Time of Arrival: December 31
10 mg	$50	在庫あり	Estimated Time of Arrival: December 31
25 mg	$80	在庫あり	Estimated Time of Arrival: December 31
50 mg	$130	在庫あり	Estimated Time of Arrival: December 31
100 mg	$230	在庫あり	Estimated Time of Arrival: December 31
200 mg		お問い合わせ
500 mg		お問い合わせ

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* アイテムを追加する前、数量をご選択ください

This product is a controlled substance and not for sale in your territory.

カスタマーレビュー

Based on 0 publication(s) in Google Scholar

Other Forms of Propionyl-DL-carnitine chloride:

Levocarnitine propionate hydrochloride 在庫あり
Propionylcarnitine 在庫あり
Propionyl-DL-carnitine chloride (Standard) お問い合わせ

Endogenous Metabolite アイソフォーム固有の製品をすべて表示:

すべてのアイソフォームを表示

Human Endogenous Metabolite Microbial Metabolite

生物活性
純度とドキュメンテーション
参考文献
カスタマーレビュー

製品説明

Propionyl-DL-carnitine chloride is a carnitine derivative. Propionyl-DL-carnitine chloride can be used for the research of inflammation^[1]^[2]^[3]^[4].

体外実験

Propionyl-DL-carnitine chloride shows protection to beta-thalassaemic erythrocytes from oxidative stress^[1].
Propionyl-DL-carnitine chloride increases production of ¹⁴CO₂ from [1-¹⁴C]pyruvate and increases the rate of formation of acetyl camitine from pyruvate^[2].
Propionyl-DL-carnitine chloride allows the endothelial cells to maintain their functionality and regulatory role on vessel activity for a longer time and decreases the formation of oxygen reactive species due to xanthine oxidase activity on hypoxanthine formed by adenine nucleotide catabolism^[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

体内実験

Propionyl-DL-carnitine chloride (2 mM/kg; p.o. once daily for 4 weeks) affects plasma and urine total carnitine concentrations of mice^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	Adult age-matched male C57BL/6 mice^[3]
Dosage:	2 mM/kg
Administration:	Oral gavage; 2 mM/kg/day for 4 weeks
Result:	Increased plasma and urine total carnitine concentrations, but showed no effect on the skeletal muscle carnitine content of mice.

分子量

253.72

分子式

C₁₀H₂₀ClNO₄

CAS 番号

18828-58-5

Appearance

Solid

Color

White to off-white

SMILES

CCC(OC(CC(O)=O)C[N+](C)(C)C)=O.[Cl-]

Structure Classification

Others

Initial Source

Endogenous metabolite

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

溶剤 & 溶解度

体外:

Methanol : 250 mg/mL (985.34 mM; Need ultrasonic)

DMSO : 100 mg/mL (394.14 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.9414 mL	19.7068 mL	39.4135 mL
5 mM	0.7883 mL	3.9414 mL	7.8827 mL
10 mM	0.3941 mL	1.9707 mL	3.9414 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

一般には略語で表示されます：C₁V₁ = C₂V₂

濃度 _（開始）

体積 _（開始）

濃度 _（終了）

体積 _（終了）

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

純度とドキュメンテーション

純度: 98.10%

Select Batch:

データシート (274 KB) SDS (394 KB)

COA (250 KB) HNMR (245 KB) RP-HPLC (244 KB) MS (208 KB)

取扱説明書 (2659 KB)

参考文献

[1]. Palmieri L, et al. Protection of beta-thalassaemic erythrocytes from oxidative stress by propionyl carnitine. Int J Tissue React. 1994;16(3):121-9. [Content Brief]

[2]. Tassani V, et al. Anaplerotic effect of propionyl carnitine in rat heart mitochondria. Biochem Biophys Res Commun. 1994 Mar 15;199(2):949-53. [Content Brief]

[3]. Morand R, et al. Effect of carnitine, acetyl-, and propionylcarnitine supplementation on the body carnitine pool, skeletal muscle composition, and physical performance in mice. Eur J Nutr. 2014 Sep;53(6):1313-25. [Content Brief]

[4]. Bertelli A, et al. Effect of propionyl carnitine on energy charge and adenine nucleotide content of cardiac endothelial cells during hypoxia. Int J Tissue React. 1991;13(1):37-40. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO / Methanol	1 mM	3.9414 mL	19.7068 mL	39.4135 mL	98.5338 mL
	5 mM	0.7883 mL	3.9414 mL	7.8827 mL	19.7068 mL
	10 mM	0.3941 mL	1.9707 mL	3.9414 mL	9.8534 mL
	15 mM	0.2628 mL	1.3138 mL	2.6276 mL	6.5689 mL
	20 mM	0.1971 mL	0.9853 mL	1.9707 mL	4.9267 mL
	25 mM	0.1577 mL	0.7883 mL	1.5765 mL	3.9414 mL
	30 mM	0.1314 mL	0.6569 mL	1.3138 mL	3.2845 mL
	40 mM	0.0985 mL	0.4927 mL	0.9853 mL	2.4633 mL
	50 mM	0.0788 mL	0.3941 mL	0.7883 mL	1.9707 mL
	60 mM	0.0657 mL	0.3284 mL	0.6569 mL	1.6422 mL
	80 mM	0.0493 mL	0.2463 mL	0.4927 mL	1.2317 mL
	100 mM	0.0394 mL	0.1971 mL	0.3941 mL	0.9853 mL