2. Search Result
Search Result
Results for "

(±)-Arginine (Standard)

" in MedChemExpress (MCE) Product Catalog:

33

Inhibitors & Agonists

2

Peptides

14

Natural
Products

Targets Recommended:
Art. -Nr. Produktname Target Forschungsgebiete Chemical Structure
  • HY-N0455R
    L-Arginine (Standard)

    		Reference Standards NO Synthase Endogenous Metabolite Cardiovascular Disease Cancer
    L-Arginine (Standard) is the analytical standard of L-Arginine. This product is intended for research and analytical applications. L-Arginine ((S)-(+)-Arginine) is the substrate for the endothelial nitric oxide synthase (eNOS) to generate NO. L-Arginine is transported into vascular smooth muscle cells by the cationic amino acid transporter family of proteins where it is metabolized to nitric oxide (NO), polyamines, or L-proline. L-Arginine is a potent vasodilator, and can be used to induce experimental acute pancreatitis .
    L-Arginine (Standard)
  • HY-N0391R
    L-Citrulline (Standard)

    		Reference Standards Endogenous Metabolite Others
    L-Citrulline (Standard) is the analytical standard of L-Citrulline. This product is intended for research and analytical applications. L-Citrulline is an amino acid derived from ornithine in the catabolism of proline or glutamine and glutamate, or from l-arginine via arginine-citrulline pathway.
    L-Citrulline (Standard)
  • HY-N0469R
    L-Lysine (Standard)

    		Reference Standards Endogenous Metabolite Virus Protease HSV Infection Metabolic Disease Inflammation/Immunology
    L-Lysine (Standard) is the analytical standard of L-Lysine. This product is intended for research and analytical applications. L-lysine is an essential amino acid for humans with orally activity. L-lysine can inhibit the occurrence of HSV infections and is used in herpes research. L-lysine increases calcium absorption, reduces diabetes-related diseases, improves gut health, and alleviates pancreatic inflammation. L-lysine can be used in research on metabolism, infection, and inflammation . IC50 & Target:L-lysine (150 mg/kg) promotes, but not initiates, bladder cancer. The administration of L-lysine to rats submitted to colovesical cystoplasty accelerates the development of transitional metaplasia of the intestinal epithelium .
    L-lysine (10 mg/kg) treatment attenuates pancreatic tissue injury induced by L-arginine by inhibiting the release of the inflammatory cytokine IL-6 and enhance antioxidant activity . In Vivo:L-lysine (10?mg/kg, p.o., pre-treated or post-treated, administration duration 15 days) treatment attenuates pancreatic tissue injury induced by L-arginine by inhibiting the release of the inflammatory cytokine IL-6 and enhance antioxidant activity in acute pancreatitis mice model . L-lysine (5 or 10?mg/kg, p.o., 45 days) ameliorates sepsis-induced acute lung injury in a lipopolysaccharide (HY-D1056)-induced mouse model .
    L-Lysine (Standard)
  • HY-101410R
    SDMA (Standard)

    Symmetric dimethylArginine (Standard); NG,NG'-Dimethyl-L-Arginine (Standard)

    		 Reference Standards Endogenous Metabolite NO Synthase NF-κB Inflammation/Immunology
    SDMA (Standard) is the analytical standard of SDMA. This product is intended for research and analytical applications. SDMA (Symmetric dimethylarginine) is an endogenous inhibitor of nitric oxide (NO) synthase activity. SDMA, a novel kidney biomarker, permits earlier diagnosis of kidney disease than traditional creatinine testing.
    SDMA (Standard)
  • HY-W105809R
    L-Arginine L-aspartate (Standard)

    (S)-2-Amino-5-((diaminomethylene)amino)pentanoic acid compound with L-aspartic acid (1:1) (Standard)

    		 Reference Standards
    L-Arginine L-aspartate (Standard) is the analytical standard of L-Arginine L-aspartate. This product is intended for research and analytical applications.
    L-Arginine L-aspartate (Standard)
  • HY-B1811R
    Vasopressin (Standard)

    Arginine vasopressin (Standard); Antidiuretic hormone (Standard)

    		 Endogenous Metabolite Reference Standards Neurological Disease
    Vasopressin (Standard) is the analytical standard of Vasopressin. This product is intended for research and analytical applications. Vasopressin is a cyclic nonapeptide that is synthesized centrally in the hypothalamus. Vasopressin participates in the hypothalamic-pituitary-adrenal axis, and regulates pituitary corticotropin secretion by potentiating the stimulatory effects of corticotropin releasing factor. Vasopressin also can act as a neurotransmitter, exerting its action by binding to specific G protein-coupled receptors .
    Vasopressin (Standard)
  • HY-W014130R
    N-Acetyl-L-arginine (Standard)

    Ac-Arg-OH (Standard)

    		 Reference Standards Endogenous Metabolite Others
    N-Acetyl-L-arginine (Ac-Arg-OH) is one of the guanidino compounds found elevated in the serum of a hemodialyzed renal insufficient (uremic) pediatric population. N-Acetyl-L-arginine shows synergistic activity with glycine buffer. N-Acetyl-L-arginine suppresses the aggregation of intravenous immunoglobulins with a minimum decrease in transition temperature. N-Acetyl-L-arginine dramatically reduces IL-1 expression in the presence of silicone oil. N-Acetyl-L-arginine also demonstrates colloidal stability .
    N-Acetyl-L-arginine (Standard)
  • HY-N0454R
    DL-Arginine (Standard)

    (±)-Arginine (Standard)

    		 Reference Standards Endogenous Metabolite Cardiovascular Disease
    DL-Arginine (Standard) is the analytical standard of DL-Arginine. This product is intended for research and analytical applications. DL-Arginine is the racemic compound of L-Arginine (HY-N0455) and D-Arginine (HY-W016781). Arginine is an essential amino acid that requires additional supplementation in traumatic or diseased conditions. Arginine is involved in T cell activation, proliferation, and differentiation, and affects the function of immune cells .
    DL-Arginine (Standard)
  • HY-N0455AR
    L-Arginine hydrochloride (Standard)

    (S)-(+)-Arginine hydrochloride (Standard)

    		 Reference Standards NO Synthase Endogenous Metabolite Cancer
    L-Arginine (hydrochloride) (Standard) is the analytical standard of L-Arginine (hydrochloride). This product is intended for research and analytical applications. L-Arginine ((S)-(+)-Arginine) is the substrate for the endothelial nitric oxide synthase (eNOS) to generate NO. L-Arginine is transported into vascular smooth muscle cells by the cationic amino acid transporter family of proteins where it is metabolized to nitric oxide (NO), polyamines, or L-proline. L-Arginine is a potent vasodilator, and can be used to induce experimental acute pancreatitis .
    L-Arginine hydrochloride (Standard)
  • HY-17000R
    Tolvaptan (Standard)

    OPC-41061 (Standard)

    		 Reference Standards Vasopressin Receptor Autophagy Cardiovascular Disease Endocrinology Cancer
    Tolvaptan (Standard) is the analytical standard of Tolvaptan. This product is intended for research and analytical applications. Tolvaptan is a selective, competitive and orally active vasopressin receptor 2 (V2R) antagonist with an IC50 of 1.28 μM for the inhibition of arginine vasopressin (AVP)-induced platelet aggregation. Tolvaptan induces cell apoposis and affects cell cycle. Tolvaptan can be used for the research of hyponatremia .
    Tolvaptan (Standard)
  • HY-18346R
    Mozavaptan (Standard)

    OPC-31260 (Standard)

    		 Vasopressin Receptor Reference Standards Cardiovascular Disease Metabolic Disease Endocrinology Cancer
    Mozavaptan (Standard) is the analytical standard of Mozavaptan. This product is intended for research and analytical applications. Mozavaptan (OPC-31260) is a benzazepine derivative and a potent, selective, competitive and orally active vasopressin V2 receptor antagonist with an IC50 of 14 nM. Mozavaptan shows ~85-fold selectivity for V2 receptor over V1 receptor (IC50 of 1.2 μM), and can antagonize the antidiuretic action of arginine vasopressin (AVP) in vivo. Mozavaptan has the potential for hyponatremia, syndrome of inappropriate antidiuretic hormone (SIADH), and congestive heart failure treatment .
    Mozavaptan (Standard)
  • HY-Y0790R
    Cuminaldehyde (Standard)

    p-Isopropylbenzaldehyde (Standard)

    		 α-synuclein Reference Standards Infection Neurological Disease Inflammation/Immunology Cancer
    Cuminaldehyde Standard is the analytical standard of Cuminaldehyde. This product is intended for research and analytical applications. Cuminaldehyde is the main component of Cuminum cyminum and has multiple biological activities, including anti-inflammatory, anti-cancer, anti-diabetic, anti-injury, anti-neuropathy and antibacterial effects. Cuminaldehyde is an inhibitor of aldose reductase (IC50= 0.00085 mg/mL) and α-glucosidase (IC50=0.5 mg/mL). Cuminaldehyde also inhibits the fibrillation of α-synuclein and prevents its aggregation Cuminaldehyde can induce apoptosis in colon adenocarcinoma cells by targeting topoisomerase I and II. In addition, Cuminaldehyde also exerts anti-inflammatory activity by inhibiting lipoxygenase. Cuminaldehyde has a strong inhibitory effect on the growth of Aspergillus flavus and the biosynthesis of aflatoxin B1 (AFB1). Cuminaldehyde can exert anti-injury and anti-neuropathy effects by participating in opioid receptors, L-arginine/NO/cGMP pathways and anti-inflammatory effects. Cuminaldehyde has potential application value in the research of neurodegenerative diseases, cancer, diabetes and neuropathic pain diseases .
    Cuminaldehyde (Standard)
  • HY-W016781R
    D-Arginine (Standard)

    H-D-Arg-OH (Standard)

    		 Reference Standards Endogenous Metabolite Neurological Disease Cancer
    D-arginine (H-D-Arg-OH) is the D-isomer of arginine. Arginine is an α-amino acid that is used in the biosynthesis of proteins. D-Arginine is an inactive form of L-arginine. D-arginine can be used in myeloma and neurological disease research . .
    D-Arginine (Standard)
  • HY-113286R
    4-Guanidinobutanoic acid (Standard)

    		Reference Standards Endogenous Metabolite Amino Acid Derivatives Neurological Disease
    4-Guanidinobutanoic acid (Standard) is the analytical standard of 4-Guanidinobutanoic acid (HY-113286). This product is intended for research and analytical applications. 4-Guanidinobutanoic acid is a common urinary metabolite and arginine metabolite. 4-Guanidinobutanoic acid can be used in the research of fibromyalgia .
    4-Guanidinobutanoic acid (Standard)
  • HY-129380AR
    Fructosyl-lysine dihydrochloride (Standard)

    Fructoselysine dihydrochloride (Standard)

    		 Endogenous Metabolite Reference Standards Metabolic Disease
    Fructosyl-lysine (dihydrochloride) (Standard) is the analytical standard of Fructosyl-lysine (dihydrochloride). This product is intended for research and analytical applications. Fructosyl-lysine (Fructoselysine) dihydrochloride is an amadori glycation product from the reaction of glucose and lysine by the Maillard reaction. Fructosyl-lysine dihydrochloride is the precursor to glucosepane, a lysine-arginine protein cross-link that can be an indicator in diabetes detection .
    Fructosyl-lysine dihydrochloride (Standard)
  • HY-34516R
    D-Ornithine hydrochloride (Standard)

    (R)-Ornithine hydrochloride (Standard)

    		 Endogenous Metabolite Bacterial Reference Standards Metabolic Disease
    D-Ornithine (hydrochloride) (Standard) is the analytical standard of D-Ornithine (hydrochloride). This product is intended for research and analytical applications. D-Ornithine ((R)-Ornithine) hydrochloride is a constituent of bacterial cell wall. D-Ornithine hydrochloride promotes the production of L-arginine (HY-N0455). D-Ornithine hydrochloride enhances the expression of pyrrolysine-containing proteins .
    D-Ornithine hydrochloride (Standard)
  • HY-W011614R
    L-Arginine ethyl ester dihydrochloride (Standard)

    		Reference Standards Others Others
    L-Arginine ethyl ester dihydrochloride (Standard) is the analytical standard of L-Arginine ethyl ester dihydrochloride. This product is intended for research and analytical applications. L-Arginine ethyl ester dihydrochloride is an arginine derivative .
    L-Arginine ethyl ester dihydrochloride (Standard)
  • HY-18962R
    AMI-1 (Standard)

    		Histone Methyltransferase Cancer
    AMI-1 (Standard) is the analytical standard of AMI-1. This product is intended for research and analytical applications. AMI-1 is a potent, cell-permeable and reversible inhibitor of protein arginine N-methyltransferases (PRMTs), with IC50s of 8.8 μM and 3.0 μM for human PRMT1 and yeast-Hmt1p, respectively. AMI-1 exerts PRMTs inhibitory effects by blocking peptide-substrate binding .
    AMI-1 (Standard)
  • HY-18962AR
    AMI-1 free acid (Standard)

    		Histone Methyltransferase Cancer
    AMI-1 (free acid) (Standard) is the analytical standard of AMI-1 (free acid). This product is intended for research and analytical applications. AMI-1 free acid is a potent, cell-permeable and reversible inhibitor of protein arginine N-methyltransferases (PRMTs), with IC50s of 8.8 μM and 3.0 μM for human PRMT1 and yeast-Hmt1p, respectively. AMI-1 free acid exerts PRMTs inhibitory effects by blocking peptide-substrate binding .
    AMI-1 free acid (Standard)
  • HY-B1202R
    Alrestatin (Standard)

    AY-22284 (Standard)

    		 Reference Standards Aldose Reductase Metabolic Disease
    Alrestatin (AY-22284) Standard is the analytical standard of Alrestatin (HY-B1202). This product is intended for research and analytical applications. Alrestatin (AY-22284) is an aldose reductase inhibitor. Alrestatin reduces fructose levels in the uterine fluid of mice. Alrestatin interferes with sperm capacitation and impairs fertilization function in mice. Alrestatin decreases basal and tyramine-induced norepinephrine release in rat pancreatic specimens in vitro. Alrestatin enhances glucose- and arginine-stimulated insulin secretion in vivo. Alrestatin can be used in studies related to diabetes and reproductive diseases.
    Alrestatin (Standard)
  • HY-123593R
    Mozavaptan hydrochloride (Standard)

    OPC-31260 hydrochloride (Standard)

    		 Vasopressin Receptor Reference Standards Cardiovascular Disease Metabolic Disease Endocrinology Cancer
    Mozavaptan (hydrochloride) (Standard) is the analytical standard of Mozavaptan (hydrochloride). This product is intended for research and analytical applications. Mozavaptan hydrochloride (OPC-31260 hydrochloride) is a benzazepine derivative and a potent, selective, competitive and orally active vasopressin V2 receptor antagonist with an IC50 of 14 nM. Mozavaptan hydrochloride shows ~85-fold selectivity for V2 receptor over V1 receptor (IC50 of 1.2 μM), and can antagonize the antidiuretic action of arginine vasopressin (AVP) in vivo. Mozavaptan hydrochloride has the potential for hyponatremia, syndrome of inappropriate antidiuretic hormone (SIADH), and congestive heart failure treatment .
    Mozavaptan hydrochloride (Standard)
  • HY-W003969R
    Aminopicoline (Standard)

    Ascensil (Standard); 2-Amino-4-methylpyridine (Standard)

    		 Reference Standards NO Synthase Others
    Aminopicoline (Standard) is the analytical standard of Aminopicoline. Aminopicoline (Ascensil) is a potent and non-selective inhibitor of nitric oxide synthase (NOS) isoenzymes (iNOS, nNOS, eNOS). Aminopicoline competes with arginine at the substrate-binding site of nitric oxide synthase, reduces cellular nitric oxide production, inhibits the elevation of plasma nitrate, increases mean arterial pressure at high doses, and also serves as a basis for radiolabeled ligands to localize nitric oxide synthase binding sites. Aminopicoline can be used in the research of diseases associated with septic shock, joint inflammation, intestinal inflammation, and CNS inflammation 。
    Aminopicoline (Standard)
  • HY-102062R
    Nω-Propyl-L-arginine (Standard)

    N-omega-Propyl-L-Arginine (Standard)

    		 Reference Standards NO Synthase Neurological Disease
    Nω-Propyl-L-arginine (Standard) is the analytical standard of Nω-Propyl-L-arginine (HY-102062). This product is intended for research and analytical applications. Nω-Propyl-L-arginine (N-omega-Propyl-L-arginine) is a potent, competitive, and highly selective inhibitor of neuronal nitric oxide synthase (nNOS), with a Ki of 57 nM. Nω-Propyl-L-arginine displays a 149-fold selectivity for nNOS over endothelial NOS (eNOS) .
    Nω-Propyl-L-arginine (Standard)
  • HY-110137R
    Furamidine dihydrochloride (Standard)

    DB75 dihydrochloride (Standard); NSC 305831 dihydrochloride (Standard)

    		 Histone Methyltransferase Phosphodiesterase (PDE) Parasite Reference Standards Infection Inflammation/Immunology Cancer
    Furamidine (dihydrochloride) (Standard) is the analytical standard of Furamidine (dihydrochloride). This product is intended for research and analytical applications. Furamidine dihydrochloride (DB75 dihydrochloride) is a selective protein arginine methyltransferase 1 (PRMT1) inhibitor with an IC50 of 9.4 μM. Furamidine dihydrochloride is selective for PRMT1 over PRMT5, PRMT6, and PRMT4 (CARM1) (IC50s of 166 μM, 283 μM, and >400 μM, respectively). Furamidine dihydrochloride is a potent, reversible and competitive tyrosyl-DNA phosphodiesterase 1 (TDP-1) inhibitor. Inhibition of TDP-1 by Furamidine dihydrochloride is effective both with single- and double-stranded DNA substrates but is slightly stronger with the duplex DNA. Furamidine dihydrochloride is also an antiparasite agent .
    Furamidine dihydrochloride (Standard)
  • HY-42034R
    Hydroquinine (Standard)

    Dihydroquinine (Standard)

    		 Reference Standards Bacterial Parasite Reactive Oxygen Species (ROS) Protein Arginine Deiminase Inflammation/Immunology
    Hydroquinine (Standard) is the analytical standard of Hydroquinine. Hydroquinine (Dihydroquinine) is an anti-bacterial agent that inhibits both Gram-positive and Gram-negative bacteria. Hydroquinine inhibits the growth of multidrug-resistant pseudomonas aeruginosa via the suppression of the arginine deiminase pathway genes. Hydroquinine inhibits Plasmodium falciparum and Plasmodium berghei. Hydroquinine displays anti-malarial and demelanizing activities. Hydroquinine effectively induces specific RND-type efflux pump systems in Pseudomonas aeruginosa, particularly the MexCD-OprJ and MexXY efflux pumps. Hydroquinine inhibits Pseudomonas aeruginosa adhesion and biofilm formation. Hydroquinine serves as a precursor for derivatives such as C9 epihydroquinine, 9-acetoxy-10,11-dihydroquinine, and 10,11-dihydroquinine monohydrochloride .
    Hydroquinine (Standard)
  • HY-100025AR
    HLCL-61 hydrochloride (Standard)

    		Histone Methyltransferase Reference Standards Apoptosis Cancer
    HLCL-61 (hydrochloride) (Standard) is the analytical standard of HLCL-61 (hydrochloride) (HY-100025A). This product is intended for research and analytical applications. HLCL-61 hydrochloride is a first-in-class inhibitor of protein arginine methyltransferase 5 (PRMT5).
    HLCL-61 hydrochloride (Standard)
  • HY-101564R
    Onametostat (Standard)

    JNJ-64619178 (Standard)

    		 Histone Methyltransferase Reference Standards Cancer
    Onametostat (Standard) is the analytical standard of Onametostat (HY-101564). This product is intended for research and analytical applications. Onametostat (JNJ-64619178) is a selective, orally active and pseudo-irreversible protein arginine methyltransferase 5 (PRMT5) inhibitor with an IC50 of 0.14 nM. Onametostat has potent activity in lung cancer .
    Onametostat (Standard)
  • HY-100565R
    SGC2085 (Standard)

    		Histone Methyltransferase Reference Standards Cancer
    SGC2085 (Standard) is the analytical standard of SGC2085 (HY-100565). This product is intended for research and analytical applications. SGC2085 is a potent and selective inhibitor of coactivator associated arginine methyltransferase 1 (CARM1) with an IC50 of 50 nM. SGC2085 also selectively inhibits PRMT6 with an IC50 value of 5.2 μM, but not other PRMT proteins .
    SGC2085 (Standard)
  • HY-107777R
    LLY-283 (Standard)

    		Reference Standards Histone Methyltransferase Cancer
    LLY-283 (Standard) is the analytical standard of LLY-283 (HY-107777). This product is intended for research and analytical applications. LLY-283, a chemical probe, is a potent, selective and oral protein arginine methyltransferase 5 (PRMT5) inhibitor, with an IC50 of 22 nM and a Kd of 6 nM for PRMT5:MEP50 complex, and shows antitumor activity .
    LLY-283 (Standard)
  • HY-103023R
    CLP290 (Standard)

    		Reference Standards Potassium Channel Neurological Disease
    CLP290 (Standard) is the analytical standard of CLP290 (HY-103023). This product is intended for research and analytical applications. CLP290 is an orally available activator of the neuron-specific K+-Cl- cotransporter KCC2, displays potential for treatment of a wide range of neurological and psychiatric indications. CLP290 can significantly lower blood arginine-vasopressin (AVP) and glucose levels in STZ (HY-13753) rats .
    CLP290 (Standard)
  • HY-101761R
    TM5441 (Standard)

    		Reference Standards PAI-1 Apoptosis Cardiovascular Disease Cancer
    TM5441 (Standard) is the analytical standard of TM5441 (HY-101761). This product is intended for research and analytical applications. TM5441 is an orally bioavailable inhibitor of plasminogen activator inhibitor-1 (PAI-1), has IC50 values between 13.9 and 51.1 μM and induces intrinsic apoptosis in several human cancer cell lines. TM5441 attenuates Nω-nitro-l-arginine methyl ester-induced cardiac hypertension and vascular senescence .
    TM5441 (Standard)
  • HY-101563R
    GSK3326595 (Standard)

    EPZ015938 (Standard)

    		 Histone Methyltransferase Reference Standards SARS-CoV MDM-2/p53 CDK Apoptosis Infection Cancer
    GSK3326595 (Standard) is the analytical standard of GSK3326595 (HY-101563). This product is intended for research and analytical applications. GSK3326595 is a protein arginine methyltransferase 5 (PRMT5) inhibitor. GSK3326595 decreases SARS-CoV-2 infection, inhibits cancer cell proliferation and induces pro-inflammatory macrophage polarization and increases hepatic triglyceride levels without affecting atherosclerosis. GSK3326595 can be used for research of relapsed/refractory mantle cell lymphoma .
    GSK3326595 (Standard)
  • HY-107574R
    TC-E 5003 (Standard)

    		Reference Standards Histone Methyltransferase AP-1 NF-κB PKA Metabolic Disease Inflammation/Immunology Cancer
    TC-E 5003 (Standard) is the analytical standard of TC-E 5003 (HY-107574). This product is intended for research and analytical applications. TC-E 5003 is a selective protein arginine methyltransferase 1 (PRMT1) inhibitor with an IC50 of 1.5 µM against hPRMT1. TC-E 5003 modulates the lipopolysaccharide (LPS) (HY-D1056)-induced AP-1 and NF-κB signaling pathways with anti-inflammatory properties. TC-E 5003 also upregulates the expression of Ucp1 and Fgf21, activates protein Kinase A signaling and lipolysis in primary subcutaneous adipocytes from both mouse and humans. TC-E 5003 is promising for research of obesity and associated metabolic disorders, oxidative stress, inflammation and cancers .
    TC-E 5003 (Standard)

Online-Anfrage

Your information is safe with us. * Required Fields.

Anrede

  

Country or Region *

Name des Antragstellers *

 

Name der Organisation *

Department *

     

E-Mail-Addresse *

 

Produktname *

Art. -Nr.

  

Requested quantity *

Telefonnummer *

     

Bemerkungen

Online-Anfrage

Inquiry Information

Produktname:
Art. -Nr.:
Menge:
MCE Japan Authorized Agent: