4-Guanidinobutanoic acid (Standard)
4-Guanidinobutanoic acid (Standard) is the analytical standard of 4-Guanidinobutanoic acid (HY-113286). This product is intended for research and analytical applications. 4-Guanidinobutanoic acid is a metabolite of arginine and an orally active SLC36A1/Hedgehog signaling pathway activator. 4-Guanidinobutanoic acid drives epithelial reprogramming, enhances intestinal stem cell function and goblet cell differentiation. 4-Guanidinobutanoic acid promotes the enrichment of Akkermansia muciniphila via mucus-dependent niche expansion, regulates intestinal homeostasis, and establishes a microbiota-host feedback loop. 4-Guanidinobutanoic acid exhibits anti-aging and healthspan-regulating properties. 4-Guanidinobutanoic acid can be used in research related to ulcerative colitis, amyotrophic lateral sclerosis, and Duchenne muscular dystrophy.
For research use only. We do not sell to patients.
- CAS No.: 463-00-3
- Formula: C5H11N3O2
- Molecular Weight:145.16
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Purity & Documentation
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Help & FAQs
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 463-00-3
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Molecular Weight 145.16
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Formula C5H11N3O2
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SMILES
O=C(O)CCCNC(N)=N
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Yang J, et al. A 4-guanidinobutanoic acid-SLC36A1 axis drives a microbiota‒host feedback loop to regulate intestinal homeostasis. Gut microbes. 2026 Dec 31;18(1):2639216. [Content Brief]
[2]. Jonk SM, et al. Metabolic analysis of sarcopenic muscle identifies positive modulators of longevity and healthspan in C. elegans. Redox biology. 2025 Sep;85:103732. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
4-Guanidinobutanoic acid (Standard) Related Classifications
HY-113286R Related Classifications
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- 4-Guanidinobutanoic acid (Standard)
- 463-00-3
- Reference Standards
- Endogenous Metabolite
- Hedgehog
- SLC36A1
- goblet cell
- ulcerative colitis
- Duchenne muscular dystrophy
- murine colonic organoids
- C. elegans
- amyotrophic lateral sclerosis
- intestinal stem cell
- Akkermansia muciniphila
- Hedgehog signaling pathway
- Inhibitor
- inhibitor
- inhibit