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Results for "

Azide-PEG2-Desthiobiotin

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Amylin Receptor (1) Amyloid-β (1) Apoptosis (1) Bacterial (1) BCL6 (1) Biochemical Assay Reagents (4) Bombesin Receptor (3) Claudin (1) Complement System (1) Drug Derivative (1) EGFR (1) Fluorescent Dye (4) Gap Junction Protein (1) GCGR (1) Integrin (1) Isotope-Labeled Compounds (1) Neurokinin Receptor (1) Neuropeptide B/W Receptor (1) NF-κB (1) PROTACs (1) Proteasome (2) RXFP Receptor (1) Src (1) Syk (1) Thyroid Hormone Receptor (1) Transmembrane Glycoprotein (2) Wnt (1) β-catenin (1)
By Research Areas:	Cancer (12) Cardiovascular Disease (2) Endocrinology (1) Infection (1) Inflammation/Immunology (5) Metabolic Disease (2) Neurological Disease (8)
Click Chemistry:	Azide (1)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Isotope-Labeled Compounds

Click Chemistry

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P11307

Biotin-epoxomicin	Proteasome	Cancer
Biotin-epoxomicin is a Proteasome subunit binder. Biotin-epoxomicin serves as an affinity reagent for identifying proteasomal catalytic subunits, and facilitates affinity purification of active proteasomal subunits for LC-MS identification. Biotin-epoxomicin can be used to study solid tumors derived from B16 melanoma ^[2].

HY-P10303

*Cyclo[Arg-Gly-Asp-D-Phe-Lys(Azide)]* Cyclo[RGDfK(Azide)]	Biochemical Assay Reagents	Others
Cyclo[Arg-Gly-Asp-D-Phe-Lys(Azide)] is the derivative of Cyclo(-RGDfK) (HY-P0023). Cyclo[Arg-Gly-Asp-D-Phe-Lys(Azide)] is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity .

HY-P11306

Biotin-(Oaa)3-epoxomicin	Proteasome NF-κB	Inflammation/Immunology
Biotin-(Oaa)₃-epoxomicin is a biotin-labeled form of Epoxomicin (HY-13821), prepared by conjugating Epoxomicin with biotin via three hydrophilic oxaacetyl amino acid (Oaa) linkers. Biotin-(Oaa)₃-epoxomicin is primarily used in proteomic studies for the capture, identification and target validation of proteasome complexes, to determine the intracellular targets of epoxomicin. Epoxomicin acts as a proteasome inhibitor and NF-κB inhibitor, which effectively blocks inflammatory responses in mouse ear edema assays. It inhibits proteasome activity via covalent binding to catalytic subunits including LMP7, X, MECL1 and Z, with the strongest inhibitory effect on chymotrypsin-like activity, and does not interfere with non-proteasomal proteases such as trypsin and papain ^[2].

HY-P10392AF

fStAx-35R TFA	Wnt β-catenin	Cancer
fStAx-35R TFA is the hydrocarbon-stapled peptide. fStAx-35R TFA inhibits Wnt/β-catenin signaling pathway by disrupting the β-catenin-TCF interaction. fStAx-35R TFA can be used in cancer research .

HY-P10620

GGGYK-Biotin	Bacterial	Others
GGGYK-Biotin is a substrate peptide designed to study the substrate specificity of Sortase A. GGGYK-Biotin can be used to develop Sortase A variants with different substrate specificities .

HY-P3576A

Biotin-Gastrin Releasing Peptide, human TFA	Fluorescent Dye Bombesin Receptor	Neurological Disease Cancer
Biotin-Gastrin Releasing Peptide, human TFA is a biotinylated gastrin releasing peptide (GRP). Gastrin-releasing peptide (GRP) is a neuropeptide with growth-stimulatory and tumorigenic properties .

HY-P2546

Biotin-Substance P	Neurokinin Receptor	Neurological Disease
Biotin-Substance P is the biotin tagged Substance P. Substance P (Neurokinin P) is a neuropeptide, acting as a neurotransmitter and as a neuromodulator in the CNS. The endogenous receptor for substance P is neurokinin 1 receptor (NK1-receptor, NK1R) .

HY-P10886

Zifogaptide	Gap Junction Protein Claudin	Inflammation/Immunology
Zifogaptide is a gap junction protein channel regulator. Zifogaptide mimics the PDZ-binding motif at the C-terminal of Claudin C and competitively interferes with the interaction between Claudin–TJP1 (ZO-1) scaffold. Zifogaptide can promote epithelial cell migration, reduce scar formation, and accelerate wound healing. Zifogaptide can be used for radiation dermatitis, skin injuries, etc .

HY-P5351A

*Hyaluronan-binding peptide, biotin* labeled TFA**	Transmembrane Glycoprotein	Inflammation/Immunology Cancer
Hyaluronan-binding peptide, biotin labeled TFA is a biological active peptide. (This peptide is a hyaluronan-binding peptide biotinylated through a C-terminal GGGSK linker. Hyaluronan (HA) is a nonsulfated glycosaminoglycan expressed in the extracellular matrix and on cell surfaces. HA plays a role in fertilization, embryonic development, wound healing, angiogenesis, leukocyte trafficking to inflamed tissues, and cancer metastasis. This peptide has been shown to block HA binding to CD44 receptors and inhibit T cell proliferation.) .

HY-P2491

*Atrial Natriuretic Peptide (1-28), human, porcine, Biotin-labeled*	Fluorescent Dye	Cardiovascular Disease Endocrinology
Atrial Natriuretic Peptide (1-28), human, porcine, Biotin-labeled, one of three mammalian natriuretic peptides (NPs), has endocrine effects on fluid homeostasis and blood pressure. Atrial Natriuretic Peptide has the potential for cardiovascular diseases research ^[2].

HY-W096120B

*Azide-PEG2-Desthiobiotin*	Biochemical Assay Reagents	Others
Azide-PEG2-Desthiobiotin is a PEG derivative consisting of desthiobiotin, 2 PEG units, and an azide group. Biotin can form a stable non-covalent bond with streptavidin. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-driven alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups .

HY-P10896

NOTA-P2-RM26	Bombesin Receptor	Cancer
NOTA-P2-RM26 is an antagonist of Bombesin (HY-P0195) analogs, and the gastrin-releasing peptide receptor (GRPR/BB2) is a molecular target for prostate cancer visualization. NOTA-P2-RM26 is labeled with ¹¹¹In and ⁶⁸Ga for prostate cancer imaging studies using PET and SPECT/CT .

HY-P2136F

Biotin-COG1410 TFA	Apoptosis	Neurological Disease Inflammation/Immunology Cancer
Biotin-COG1410 TFA is a biotin labled COG1410 (HY-P2136). COG1410 is an apolipoprotein E-derived peptide and an apoptosis inhibitor. COG1410 exerts neuroprotective and antiinflammatory effects in a murine model of traumatic brain injury (TBI). COG1410 can be used for the research of neurological disease ^[2].

HY-P11118A

Biotinylated CCDC61 peptide TFA CAPture peptide, biotin-CCDC61 (334-366) TFA	Biochemical Assay Reagents	Others
Biotinylated CCDC61 peptide (CAPture peptide, biotin-CCDC61 (334-366)) TFA is a biotinylated peptide derived from the centrosomal protein CCDC61. Biotinylated CCDC61 peptide TFA specifically isolates intact centrosomes .

HY-P3844

Biotinyl-neuropeptide W-23 (human)	Transmembrane Glycoprotein Neuropeptide B/W Receptor	Neurological Disease
Biotinyl-neuropeptide W-23 (human) is a biotinylated Neuropeptide W-23 (human) (HY-P1035). Neuropeptide W-23 (human) is an agonist of NPBW1 (GPR7) and NPBW2 (GPR8) ^[2].

HY-P2549

Biotin-β-Amyloid (1-40)	Fluorescent Dye	Neurological Disease
Biotin-β-Amyloid (1-40) is a N-terminal-labelled biotinylated amyloid-β-(1-40) peptide.

HY-P2510

Parathyroid Hormone (1-34), human, biotinylated	Thyroid Hormone Receptor	Metabolic Disease
Parathyroid Hormone (1-34), human, biotinylated is a probe for the parathyroid hormone receptor, can be used for analyzing the interaction between parathyroid hormone and parathyroid hormone receptors in living cells and for purifying hormone-receptor complexes with affinity columns ^[2].

HY-P10569

Biotin HER-2 substrate peptide	EGFR	Cancer
Biotin HER-2 substrate peptide is a substrate of Her4 and Her2/neu tyrosine kinase with a K_m value of 60 μm for Her2/neu kinase domain .

HY-13443F

*Exendin 4, biotin* labeled** Lys27(Biotin)-Exendin 4	GCGR	Others
Exendin 4, biotin labeled is a biotin labeled Exendin 4 (HY-13443). Exendin 4 is a long-acting GLP-1 receptor agonist .

HY-169232

PCC16 chloride	PROTACs	Cancer
PCC16 chloride is a CRBN-based cp-PCC with an IC₅₀ value of 102 nM for the degradation of DHHC3. PCC16 chloride has antitumor activity. (Target protein ligand: HY-169235, linker: HY-169236, E3 ligase ligand: HY-10984) .

HY-P2551

Biotin-β-Amyloid (17-40)	Amyloid-β	Neurological Disease
Biotin-β-Amyloid (17-40) is a N-terminal-labelled biotinylated amyloid-β(1-40) peptide. β-Amyloid (17-40) is a 24-residue fragment of the Aβ protein via post-translational processing of amyloid precursor protein (APP) .

HY-P11118

Biotinylated CCDC61 peptide CAPture peptide, biotin-CCDC61 (334-366)	Biochemical Assay Reagents	Others
Biotinylated CCDC61 peptide (CAPture peptide, biotin-CCDC61 (334-366)) is a biotinylated peptide derived from the centrosomal protein CCDC61. Biotinylated CCDC61 peptide specifically isolates intact centrosomes .

HY-P2504

*Syk Kinase Peptide Substrate, Biotin* labeled**	Syk	Others
Syk Kinase Peptide Substrate, Biotin labeled is a biotin-labled Syk kinase peptide substrate.

HY-P3576

Biotin-Gastrin Releasing Peptide, human	Fluorescent Dye Bombesin Receptor	Neurological Disease Cancer
Biotin-Gastrin Releasing Peptide, human is a biotinylated gastrin releasing peptide (GRP). Gastrin-releasing peptide (GRP) is a neuropeptide with growth-stimulatory and tumorigenic properties .

HY-P10566

BCOR(498-514), biotinylated	BCL6	Cancer
BCOR(498-514), biotinylated is the minimal BCL6 binding domain with an K_D value of 1.32 µM. BCOR(498-514), biotinylated blocks BCL6-mediated transcriptional repression and kills lymphoma cells .

HY-P10372

pFYN peptide	Src	Cancer
pFYN peptide is a biotin-labled phosphorylated peptide substrate derived from FYN (a Src family kinase) .

HY-P11461

Biotin-CRF, human, rat Biotin-corticotropin releasing factor	Drug Derivative	Neurological Disease
Biotin-CRF, human, rat is a biotin-conjugated CRF (human, rat). CRF (human, rat) is a corticotropin-releasing hormone, paraventricular hypothalamic nucleus marker ^[2].

HY-P11625

R9-13	RXFP Receptor	Cardiovascular Disease
R9-13 is a fatty acid-conjugated relaxin and an agonist of LGR7 (RXFP1). R9-13 induces sustained pubic symphysis elongation in estrogen-pretreated mice. R9-13 exhibits long-acting pharmacokinetic profiles in rodents, with in vivo activity lasting up to one week after administration. R9-13 can be used in studies related to acute heart failure .

HY-P11830

UDA-6	Amylin Receptor	Metabolic Disease
UDA-6 is a potent calcitonin and amylin receptor agonist (DACRA). UDA-6 induces weight loss, improves metabolic and hepatic parameters, and stabilizes active receptor states in obesity rats. UDA-6 can be used for the research of obesity .

HY-P11596

NOTA-Asp2-αvβ6L	Integrin	Cancer
NOTA-Asp2-αvβ6L is an integrin αvβ6 binder with selective accumulation in αvβ6-positive pancreatic cancer cells and tumors. NOTA-Asp2-αvβ6L can be used as a PET/CT tracer for imaging pancreatic ductal adenocarcinoma (PDAC) .

HY-P3252AS

Pegcetacoplan-13C3,15N TFA	Isotope-Labeled Compounds Complement System	Inflammation/Immunology
Pegcetacoplan- ¹³C₃, ¹⁵N TFA is the ¹³C- and ¹⁵N-labeled Pegcetacoplan TFA. Pegcetacoplan is a pegylated complement C3/C3b inhibitor. Pegcetacoplan acts by specifically binding to and inhibiting C3 and C3b, thereby suppressing the complement cascade at its proximal stage. Pegcetacoplan is not a known inhibitor or inducer of CYP450 isoenzymes. Pegcetacoplan can be used for the research of complement-mediated diseases, including paroxysmal nocturnal hemoglobinuria (PNH) and age-related macular degeneration (AMD).

Cat. No.	Product Name	Type

HY-W096120B

*Azide-PEG2-Desthiobiotin*	Biochemical Assay Reagents
Azide-PEG2-Desthiobiotin is a PEG derivative consisting of desthiobiotin, 2 PEG units, and an azide group. Biotin can form a stable non-covalent bond with streptavidin. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-driven alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups .

Azide-PEG2-Desthiobiotin

Biochemical Assay Reagents

Azide-PEG2-Desthiobiotin is a PEG derivative consisting of desthiobiotin, 2 PEG units, and an azide group. Biotin can form a stable non-covalent bond with streptavidin. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-driven alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups .

Cat. No.	Product Name	Target	Research Area

HY-P11307

Biotin-epoxomicin	Proteasome	Cancer
Biotin-epoxomicin is a Proteasome subunit binder. Biotin-epoxomicin serves as an affinity reagent for identifying proteasomal catalytic subunits, and facilitates affinity purification of active proteasomal subunits for LC-MS identification. Biotin-epoxomicin can be used to study solid tumors derived from B16 melanoma ^[2].

HY-P10303

*Cyclo[Arg-Gly-Asp-D-Phe-Lys(Azide)]* Cyclo[RGDfK(Azide)]	Biochemical Assay Reagents	Others
Cyclo[Arg-Gly-Asp-D-Phe-Lys(Azide)] is the derivative of Cyclo(-RGDfK) (HY-P0023). Cyclo[Arg-Gly-Asp-D-Phe-Lys(Azide)] is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity .

HY-P11306

Biotin-(Oaa)3-epoxomicin	Proteasome NF-κB	Inflammation/Immunology
Biotin-(Oaa)₃-epoxomicin is a biotin-labeled form of Epoxomicin (HY-13821), prepared by conjugating Epoxomicin with biotin via three hydrophilic oxaacetyl amino acid (Oaa) linkers. Biotin-(Oaa)₃-epoxomicin is primarily used in proteomic studies for the capture, identification and target validation of proteasome complexes, to determine the intracellular targets of epoxomicin. Epoxomicin acts as a proteasome inhibitor and NF-κB inhibitor, which effectively blocks inflammatory responses in mouse ear edema assays. It inhibits proteasome activity via covalent binding to catalytic subunits including LMP7, X, MECL1 and Z, with the strongest inhibitory effect on chymotrypsin-like activity, and does not interfere with non-proteasomal proteases such as trypsin and papain ^[2].

HY-P10392AF

fStAx-35R TFA	Wnt β-catenin	Cancer
fStAx-35R TFA is the hydrocarbon-stapled peptide. fStAx-35R TFA inhibits Wnt/β-catenin signaling pathway by disrupting the β-catenin-TCF interaction. fStAx-35R TFA can be used in cancer research .

HY-P10620

GGGYK-Biotin	Bacterial	Others
GGGYK-Biotin is a substrate peptide designed to study the substrate specificity of Sortase A. GGGYK-Biotin can be used to develop Sortase A variants with different substrate specificities .

HY-P3576A

Biotin-Gastrin Releasing Peptide, human TFA	Fluorescent Dye Bombesin Receptor	Neurological Disease Cancer
Biotin-Gastrin Releasing Peptide, human TFA is a biotinylated gastrin releasing peptide (GRP). Gastrin-releasing peptide (GRP) is a neuropeptide with growth-stimulatory and tumorigenic properties .

HY-P10244F

Biotin-YVAD-FMK	Peptides	Infection
Biotin-YVAD-FMK is an inhibitor for vacuolar processing enzyme (VPE), with a 64% inhibition at 5 μM. Biotin-YVAD-FMK is an irreversible substrate for caspase 1 ^[2].

HY-P2546

Biotin-Substance P	Neurokinin Receptor	Neurological Disease
Biotin-Substance P is the biotin tagged Substance P. Substance P (Neurokinin P) is a neuropeptide, acting as a neurotransmitter and as a neuromodulator in the CNS. The endogenous receptor for substance P is neurokinin 1 receptor (NK1-receptor, NK1R) .

HY-P10886

Zifogaptide	Gap Junction Protein Claudin	Inflammation/Immunology
Zifogaptide is a gap junction protein channel regulator. Zifogaptide mimics the PDZ-binding motif at the C-terminal of Claudin C and competitively interferes with the interaction between Claudin–TJP1 (ZO-1) scaffold. Zifogaptide can promote epithelial cell migration, reduce scar formation, and accelerate wound healing. Zifogaptide can be used for radiation dermatitis, skin injuries, etc .

HY-P5351A

*Hyaluronan-binding peptide, biotin* labeled TFA**	Transmembrane Glycoprotein	Inflammation/Immunology Cancer
Hyaluronan-binding peptide, biotin labeled TFA is a biological active peptide. (This peptide is a hyaluronan-binding peptide biotinylated through a C-terminal GGGSK linker. Hyaluronan (HA) is a nonsulfated glycosaminoglycan expressed in the extracellular matrix and on cell surfaces. HA plays a role in fertilization, embryonic development, wound healing, angiogenesis, leukocyte trafficking to inflamed tissues, and cancer metastasis. This peptide has been shown to block HA binding to CD44 receptors and inhibit T cell proliferation.) .

HY-P2491

*Atrial Natriuretic Peptide (1-28), human, porcine, Biotin-labeled*	Fluorescent Dye	Cardiovascular Disease Endocrinology
Atrial Natriuretic Peptide (1-28), human, porcine, Biotin-labeled, one of three mammalian natriuretic peptides (NPs), has endocrine effects on fluid homeostasis and blood pressure. Atrial Natriuretic Peptide has the potential for cardiovascular diseases research ^[2].

HY-P10896

NOTA-P2-RM26	Bombesin Receptor	Cancer
NOTA-P2-RM26 is an antagonist of Bombesin (HY-P0195) analogs, and the gastrin-releasing peptide receptor (GRPR/BB2) is a molecular target for prostate cancer visualization. NOTA-P2-RM26 is labeled with ¹¹¹In and ⁶⁸Ga for prostate cancer imaging studies using PET and SPECT/CT .

HY-P2136F

Biotin-COG1410 TFA	Apoptosis	Neurological Disease Inflammation/Immunology Cancer
Biotin-COG1410 TFA is a biotin labled COG1410 (HY-P2136). COG1410 is an apolipoprotein E-derived peptide and an apoptosis inhibitor. COG1410 exerts neuroprotective and antiinflammatory effects in a murine model of traumatic brain injury (TBI). COG1410 can be used for the research of neurological disease ^[2].

HY-P11118A

Biotinylated CCDC61 peptide TFA CAPture peptide, biotin-CCDC61 (334-366) TFA	Biochemical Assay Reagents	Others
Biotinylated CCDC61 peptide (CAPture peptide, biotin-CCDC61 (334-366)) TFA is a biotinylated peptide derived from the centrosomal protein CCDC61. Biotinylated CCDC61 peptide TFA specifically isolates intact centrosomes .

HY-P3844

Biotinyl-neuropeptide W-23 (human)	Transmembrane Glycoprotein Neuropeptide B/W Receptor	Neurological Disease
Biotinyl-neuropeptide W-23 (human) is a biotinylated Neuropeptide W-23 (human) (HY-P1035). Neuropeptide W-23 (human) is an agonist of NPBW1 (GPR7) and NPBW2 (GPR8) ^[2].

HY-P2549

Biotin-β-Amyloid (1-40)	Fluorescent Dye	Neurological Disease
Biotin-β-Amyloid (1-40) is a N-terminal-labelled biotinylated amyloid-β-(1-40) peptide.

HY-P2510

Parathyroid Hormone (1-34), human, biotinylated	Thyroid Hormone Receptor	Metabolic Disease
Parathyroid Hormone (1-34), human, biotinylated is a probe for the parathyroid hormone receptor, can be used for analyzing the interaction between parathyroid hormone and parathyroid hormone receptors in living cells and for purifying hormone-receptor complexes with affinity columns ^[2].

HY-P10569

Biotin HER-2 substrate peptide	EGFR	Cancer
Biotin HER-2 substrate peptide is a substrate of Her4 and Her2/neu tyrosine kinase with a K_m value of 60 μm for Her2/neu kinase domain .

HY-P5351

*Hyaluronan-binding peptide, biotin* labeled**	Peptides	Others
Hyaluronan-binding peptide, biotin labeled is a biological active peptide. (This peptide is a hyaluronan-binding peptide biotinylated through a C-terminal GGGSK linker. Hyaluronan (HA) is a nonsulfated glycosaminoglycan expressed in the extracellular matrix and on cell surfaces. HA plays a role in fertilization, embryonic development, wound healing, angiogenesis, leukocyte trafficking to inflamed tissues, and cancer metastasis. This peptide has been shown to block HA binding to CD44 receptors and inhibit T cell proliferation.)

HY-13443F

*Exendin 4, biotin* labeled** Lys27(Biotin)-Exendin 4	GCGR	Others
Exendin 4, biotin labeled is a biotin labeled Exendin 4 (HY-13443). Exendin 4 is a long-acting GLP-1 receptor agonist .

HY-169232

PCC16 chloride	PROTACs	Cancer
PCC16 chloride is a CRBN-based cp-PCC with an IC₅₀ value of 102 nM for the degradation of DHHC3. PCC16 chloride has antitumor activity. (Target protein ligand: HY-169235, linker: HY-169236, E3 ligase ligand: HY-10984) .

HY-P2551

Biotin-β-Amyloid (17-40)	Amyloid-β	Neurological Disease
Biotin-β-Amyloid (17-40) is a N-terminal-labelled biotinylated amyloid-β(1-40) peptide. β-Amyloid (17-40) is a 24-residue fragment of the Aβ protein via post-translational processing of amyloid precursor protein (APP) .

HY-P11118

Biotinylated CCDC61 peptide CAPture peptide, biotin-CCDC61 (334-366)	Biochemical Assay Reagents	Others
Biotinylated CCDC61 peptide (CAPture peptide, biotin-CCDC61 (334-366)) is a biotinylated peptide derived from the centrosomal protein CCDC61. Biotinylated CCDC61 peptide specifically isolates intact centrosomes .

HY-P2504

*Syk Kinase Peptide Substrate, Biotin* labeled**	Syk	Others
Syk Kinase Peptide Substrate, Biotin labeled is a biotin-labled Syk kinase peptide substrate.

HY-P3576

Biotin-Gastrin Releasing Peptide, human	Fluorescent Dye Bombesin Receptor	Neurological Disease Cancer
Biotin-Gastrin Releasing Peptide, human is a biotinylated gastrin releasing peptide (GRP). Gastrin-releasing peptide (GRP) is a neuropeptide with growth-stimulatory and tumorigenic properties .

HY-P4078

*(Arg)9 biotin* labeled**	Peptides	Others
(Arg)9 biotin labeled is a cell-permeable peptide. (Arg)9 biotin labeled can be used for drug delivery. (Arg)9 biotin labeled can traverse the plasma membrane of eukaryotic cells .

HY-P10566

BCOR(498-514), biotinylated	BCL6	Cancer
BCOR(498-514), biotinylated is the minimal BCL6 binding domain with an K_D value of 1.32 µM. BCOR(498-514), biotinylated blocks BCL6-mediated transcriptional repression and kills lymphoma cells .

HY-P10372

pFYN peptide	Src	Cancer
pFYN peptide is a biotin-labled phosphorylated peptide substrate derived from FYN (a Src family kinase) .

HY-P11461

Biotin-CRF, human, rat Biotin-corticotropin releasing factor	Drug Derivative	Neurological Disease
Biotin-CRF, human, rat is a biotin-conjugated CRF (human, rat). CRF (human, rat) is a corticotropin-releasing hormone, paraventricular hypothalamic nucleus marker ^[2].

HY-P11625

R9-13	RXFP Receptor	Cardiovascular Disease
R9-13 is a fatty acid-conjugated relaxin and an agonist of LGR7 (RXFP1). R9-13 induces sustained pubic symphysis elongation in estrogen-pretreated mice. R9-13 exhibits long-acting pharmacokinetic profiles in rodents, with in vivo activity lasting up to one week after administration. R9-13 can be used in studies related to acute heart failure .

HY-P11830

UDA-6	Amylin Receptor	Metabolic Disease
UDA-6 is a potent calcitonin and amylin receptor agonist (DACRA). UDA-6 induces weight loss, improves metabolic and hepatic parameters, and stabilizes active receptor states in obesity rats. UDA-6 can be used for the research of obesity .

HY-P11596

NOTA-Asp2-αvβ6L	Integrin	Cancer
NOTA-Asp2-αvβ6L is an integrin αvβ6 binder with selective accumulation in αvβ6-positive pancreatic cancer cells and tumors. NOTA-Asp2-αvβ6L can be used as a PET/CT tracer for imaging pancreatic ductal adenocarcinoma (PDAC) .

HY-P3252AS

Pegcetacoplan-13C3,15N TFA	Isotope-Labeled Compounds Complement System	Inflammation/Immunology
Pegcetacoplan- ¹³C₃, ¹⁵N TFA is the ¹³C- and ¹⁵N-labeled Pegcetacoplan TFA. Pegcetacoplan is a pegylated complement C3/C3b inhibitor. Pegcetacoplan acts by specifically binding to and inhibiting C3 and C3b, thereby suppressing the complement cascade at its proximal stage. Pegcetacoplan is not a known inhibitor or inducer of CYP450 isoenzymes. Pegcetacoplan can be used for the research of complement-mediated diseases, including paroxysmal nocturnal hemoglobinuria (PNH) and age-related macular degeneration (AMD).

Cat. No.	Product Name	Chemical Structure

HY-P3252AS

Pegcetacoplan-13C3,15N TFA

Pegcetacoplan- ¹³C₃, ¹⁵N TFA is the ¹³C- and ¹⁵N-labeled Pegcetacoplan TFA. Pegcetacoplan is a pegylated complement C3/C3b inhibitor. Pegcetacoplan acts by specifically binding to and inhibiting C3 and C3b, thereby suppressing the complement cascade at its proximal stage. Pegcetacoplan is not a known inhibitor or inducer of CYP450 isoenzymes. Pegcetacoplan can be used for the research of complement-mediated diseases, including paroxysmal nocturnal hemoglobinuria (PNH) and age-related macular degeneration (AMD).

Cat. No.	Product Name		Classification

HY-P10303

*Cyclo[Arg-Gly-Asp-D-Phe-Lys(Azide)]* Cyclo[RGDfK(Azide)]		Azide
Cyclo[Arg-Gly-Asp-D-Phe-Lys(Azide)] is the derivative of Cyclo(-RGDfK) (HY-P0023). Cyclo[Arg-Gly-Asp-D-Phe-Lys(Azide)] is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity .

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