Search Result
Results for "
Boc-C5-O-C5-O-C6-Cl
" in MedChemExpress (MCE) Product Catalog:
13
Biochemical Assay Reagents
3
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-P1449
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ADC Linker
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Cancer
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Boc-Gly-Gly-Phe-Gly-OH, a self-assembly of N- and C-protected tetrapeptide, is a protease cleavable linker used for the antibody-drug conjugate (ADC).
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- HY-W008034
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Fmoc-L-Trp(Boc)-OH
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Amino Acid Derivatives
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Cancer
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Fmoc-Trp(Boc)-OH (Fmoc-L-Trp(Boc)-OH) is an amino acid derivative with protective groups. Fmoc-Trp(Boc)-OH can self-assemble into stable and pH-responsive spherical nanoparticles, which can load and release bioactive molecules, with good biocompatibility and high cell uptake rate. Fmoc-Trp(Boc)-OH can be used in research on drug delivery .
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- HY-W019799
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ADC Linker
PROTAC Linkers
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Cancer
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Amino-PEG8-Boc is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Amino-PEG8-Boc is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-115391
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Boc-Leu-Arg-Arg-AMC
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Biochemical Assay Reagents
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Others
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Boc-LRR-AMC (Boc-Leu-Arg-Arg-AMC) is a fluorogenic substrate, which can be utilized for detecting the trypsin-like activity of the 26S proteasome or the 20S proteasome core .
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- HY-P1795
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Formyl Peptide Receptor (FPR)
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Inflammation/Immunology
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Boc-dPhe-Leu-dPhe-Leu-Phe (Boc-fLfLF) is a selective N-formyl peptide receptor1 (FPR1) antagonist. Boc-dPhe-Leu-dPhe-Leu-Phe inhibits fMIFL(HY-P0224)-induced NADPH oxidase activity. Boc-dPhe-Leu-dPhe-Leu-Phe can be used for the study of inflammation .
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- HY-40020
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- HY-41121
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Boc-Ala-OH
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Amino Acid Derivatives
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Cancer
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Boc-L-Ala-OH (Boc-Ala-OH) is a single N-protected amino acid ligand and a protected L-alanine derivative. Boc-L-Ala-OH promotes Pd (II)-catalyzed enantioselective C-H alkenylation and kinetic resolution. Boc-L-Ala-OH serves as a coupling reagent for the synthesis of liver-targeted glycogen phosphorylase inhibitors and P6A metabolites, and also acts as a negative control in synthesis studies of betulinic acid amino acid esters. Boc-L-Ala-OH is applicable to research on epidermoid squamous cell carcinoma .
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- HY-40114
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- HY-W008325
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Amino Acid Derivatives
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Others
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Boc-L-Dap-OH is a Boc-protected derivative of L-2,3-diaminopropionic acid. Boc-L-Dap-OH is an important chiral amino acid derivative. Boc-L-Dap-OH can be generated via the Hofmann rearrangement of Boc-L-asparagine. Boc-L-Dap-OH serves as a starting material for the preparation of BIM analogs .
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- HY-W012001
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PROTAC Linkers
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Cancer
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Boc-7-Aminoheptanoic acid can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applications. Boc-7-Aminoheptanoic acid is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.
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- HY-P2237
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- HY-P2008
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IEGR-AMC
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Factor Xa
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Cardiovascular Disease
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Boc-Ile-Glu-Gly-Arg-AMC (IEGR-AMC) is an activated factor X (FXa) specific fluorogenic peptide substrate used for Factor VIII determination .
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- HY-123109
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VH032-Boc
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Ligands for E3 Ligase
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Cancer
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(S,R,S)-AHPC-Boc (VH032-Boc) is a ligand used in the recruitment of the von Hippel-Lindau (VHL) protein. (S,R,S)-AHPC-Boc is used in PROTAC technology .
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- HY-W007729
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Biochemical Assay Reagents
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Others
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Boc-L-Alaninol is a Boc-protected chiral amino alcohol. Boc-L-Alaninol can be used in the synthesis of optically active bipyridine-containing polymers .
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- HY-W007529
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PROTAC Linkers
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Cancer
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Boc-6-aminohexanoic acid is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-P2355
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Boc2; Boc-Phe-dLeu-Phe-dLeu-Phe
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Formyl Peptide Receptor (FPR)
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Inflammation/Immunology
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BOC-FlFlF (Boc-Phe-dLeu-Phe-dLeu-Phe) is a selective FPR1 antagonist. Boc-FlFlF has an apparent dissociation constant (KD) of 230 nM as determined by the intracellular calcium mobilization assay. Boc-FlFlF can be used for the study of inflammation .
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- HY-W041856
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Boc-8-aminooctanoic acid
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PROTAC Linkers
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Cancer
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N-Boc-8-amino-octanoic acid (Boc-8-aminooctanoic acid) can be used as a PROTAC linker in the synthesis of PROTACs. N-Boc-8-amino-octanoic acid is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.
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- HY-P4548
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Boc-RVRR-AMC
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Furin
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Others
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Boc-Arg-Val-Arg-Arg-AMC hydrochloride (Boc-RVRR-AMC) is a synthetic fluorogenic substrate that is efficiently cleaved by furin .
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- HY-W101935
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N-Boc-D-arginine hydrochloride
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Amino Acid Derivatives
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Others
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N-Boc-D-Arg hydrochloride (N-Boc-D-arginine hydrochloride) is an amino acid derivative with a Boc protecting group, which can be used to synthesize desmopressin with the effects of improving nocturia, urinary incontinence and enuresis .
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- HY-W077219
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Boc-Arg(Mtr)-OH
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Amino Acid Derivatives
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Others
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Boc-L-Arg(Mtr)-OH (Boc-Arg(Mtr)-OH) is an amino acid derivative with a Boc protecting group, which can be used to synthesize peptides with antithrombotic activity .
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- HY-123109A
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(S,S,S)-VH032-Boc
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Ligands for E3 Ligase
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Cancer
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(S,S,S)-AHPC-Boc is the isomer of (S,R,S)-AHPC-Boc (HY-123109), and can be used as an experimental control. (S,R,S)-AHPC-Boc (VH032-Boc) is a ligand used in the recruitment of the von Hippel-Lindau (VHL) protein. (S,R,S)-AHPC-Boc is used in PROTAC technology .
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- HY-40091
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1-Boc-3-aminopyrrolidine
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Biochemical Assay Reagents
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Others
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1-Boc-3-Aminopyrrolidine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W011321
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- HY-W009229
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Biochemical Assay Reagents
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Others
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Boc-Glu(OtBu)-OH is a protected glutamic acid derivative with two protecting groups: Boc- and OTBu. Boc-Glu(OtBu)-OH can be used in the study of peptide compound synthesis .
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- HY-W007743
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- HY-W008919
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N-Alpha,N-epsilon-di-Boc-L-lysine 4-nitrophenyl ester
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Amino Acid Derivatives
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Others
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Boc-Lys(Boc)-Onp (N-Alpha,N-epsilon-di-Boc-L-lysine 4-nitrophenyl ester) is a lysine with a Boc protecting group. Boc-Lys(Boc)-Onp was used as a substrate for a catalyst model to study its enzymatic hydrolysis reaction catalyzed by a copper(II) complex .
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- HY-W101495
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N-Boc-L-leucine monohydrate
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Amino Acid Derivatives
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Others
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Boc-Leu-OH hydrate (N-Boc-L-leucine monohydrate) is an amino acid derivative with a Boc protecting group, which can be used to synthesize L-prolyl-L-leucyl-glycinamide peptide, a peptide mimetic with dopamine receptor modulatory activity .
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- HY-148549
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- HY-79096
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- HY-W002299
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Boc-D-Leu-OH hydrate
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Amino Acid Derivatives
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Neurological Disease
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Boc-D-Leucine monohydrate (Boc-D-Leu-OH hydrate) is an N-Boc-protected form of D-Leucine. D-Leucine is an unnatural isomer of L-Leucine that acts as an auto-inhibitor of lactic streptococci. D-Leucine shows potent anti-seizure effect .
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- HY-40021
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N-Boc-2-Piperidone
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Biochemical Assay Reagents
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Others
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1-Boc-2-piperidone is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W008633
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- HY-P4458
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Ser/Thr Protease
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Cancer
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Boc-QAR-pNA is a chromogenic substrate of trypsin. Boc-QAR-pNA can be used to test trypsin activity .
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- HY-W013781
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Biochemical Assay Reagents
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Others
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Boc-Glu(OBzl)-OH (Compound 9) is a glutamic acid derivative commonly used in Boc SPPS. Glutamic acid residues increase the hydrophilicity of the polypeptide and play an important structural and receptor binding role .
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- HY-W009673
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N-Boc-L-pyroglutamic acid
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Amino Acid Derivatives
Biochemical Assay Reagents
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Others
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Boc-Pyr-OH is a Boc-protected pyroglutamic acid derivative. Boc-Pyr-OH stabilizes the amino group of pyroglutamic acid through the Boc protecting group, preventing unwanted reactions during peptide synthesis. Boc-Pyr-OH can be used in the research of thyrotropin-releasing hormone (TRH) synthesis .
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- HY-W088151
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- HY-138370
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PROTAC Linkers
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Cancer
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Boc-NH-PEG4-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-41912B
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Boc-D-Nle-OH; N-Boc-D-norleucine
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Amino Acid Derivatives
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Others
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Boc-D-norleucine (Boc-D-Nle-OH) is a leucine derivative that can be used for peptide synthesis .
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- HY-41631
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(S)-Ethyl-N-Boc-pyroglutamate
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Amino Acid Derivatives
Drug Intermediate
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Others
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Boc-Pyr-Oet ((S)-Ethyl-N-Boc-pyroglutamate) is a derivative of L-Pyroglutamic acid (HY-76082). Boc-Pyr-Oet can be used for the synthesis of agents or other compounds.
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- HY-141198
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PROTAC Linkers
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Cancer
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Boc-NH-PEG2-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-W089232
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PROTAC Linkers
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Cancer
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Boc-10-Aminodecanoic acid can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applications. Boc-10-Aminodecanoic acid is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.
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- HY-W003605
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N-Boc-D-pyroglutamic acid ethyl ester
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Biochemical Assay Reagents
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Others
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Boc-D-Pyr-Oet (N-Boc-D-pyroglutamic acid ethyl ester) is used as a biochemical assay reagent .
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- HY-W019939
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ADC Linker
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Cancer
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Hydroxy-PEG10-Boc is extacted from patent CN108707228 (example 0024) . Hydroxy-PEG10-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG10-Boc can be conjugated to Paclitaxel (HY-B0015) or docetaxel (HY-B0011) .
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- HY-W010835
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Boc-S-trityl-D-cysteine
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Amino Acid Derivatives
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Others
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Boc-D-Cys(Trt)-OH (Boc-S-trityl-D-cysteine) is an amino acid derivative with a Boc protecting group, which can be used to synthesize the bicyclic depsipeptide histone deacetylase inhibitor spirocysteine .
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- HY-W101723
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PROTAC Linkers
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Cancer
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Boc-12-Ado-OH can be used as a PROTAC linker in the synthesis of PROTACs. Boc-12-Ado-OH is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.
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- HY-60218
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Biochemical Assay Reagents
Drug Intermediate
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Cancer
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1-Boc-3-(hydroxymethyl)pyrrolidine is an intermediate. 1-Boc-3-(hydroxymethyl)pyrrolidine can be used to synthesize a FGFR1/2/3/4 inhibitor (Compound 2). 1-Boc-3-(hydroxymethyl)pyrrolidine can be used in cancer research .
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- HY-141253
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Biochemical Assay Reagents
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Others
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N-Boc-Tris is a protective reagent. N-Boc-Tris can utilize the Boc protecting group to protect amino groups in fields such as organic synthesis and pharmaceutical research and development, thereby avoiding unnecessary side reactions.
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- HY-W014692
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N-t-Boc-amino-D-alanine; Boc-D-Dap-OH
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Amino Acid Derivatives
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Others
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Boc-D-2,3-diaminopropionic acid (N-t-Boc-amino-D-alanine) is an amino acid derivative with a Boc protecting group, which can be used to synthesize a potent NMDA receptor glycine site agonist with GluN2 subunit-specific activity .
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- HY-P2355A
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Boc2 TFA; Boc-Phe-dLeu-Phe-dLeu-Phe TFA
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Formyl Peptide Receptor (FPR)
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Inflammation/Immunology
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BOC-FlFlF (TFA) (Boc-Phe-dLeu-Phe-dLeu-Phe (TFA)) is a selective FPR1 antagonist. BOC-FlFlF has an apparent dissociation constant (KD) of 230 nM as determined by the intracellular calcium mobilization assay. BOC-FlFlF can be used for the study of inflammation .
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- HY-W753820A
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Boc-Leu-Arg-Arg-AMC TFA
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Biochemical Assay Reagents
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Others
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Boc-LRR-AMC TFA (Boc-Leu-Arg-Arg-AMC TFA) is the TFA salt form of Boc-LRR-AMC (HY-115391). Boc-LRR-AMC TFA is a fluorogenic substrate, which can be utilized for detecting the trypsin-like activity of the 26S proteasome or the 20S proteasome core .
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- HY-W003605A
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Amino Acid Derivatives
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Others
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1-Boc-DL-Pyroglutamic acid ethyl ester is a Boc-protected Pyroglutamic acid derivative, can be used for the synthesis of agents or other compounds .
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- HY-P4716
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Amino Acid Derivatives
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Inflammation/Immunology
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Boc-D-Trp(For)-OH, containing the amino acid tryptophan, is synthesized by the ammonolysis of Boc-protected D-alanine, followed by cyclization to form a dipeptide with ninhydrin. Boc-D-Trp(For)-OH has pharmacological properties, including inhibition of growth hormone release, induction of sleep and antiinflammatory .
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- HY-400312
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- HY-P5834
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- HY-P2669
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- HY-P10060
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- HY-P2715
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- HY-138335
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PROTAC Linkers
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Cancer
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Boc-PEG8-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-138473
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PROTAC Linkers
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Cancer
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Boc-PEG1-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-W048332
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- HY-W129194
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- HY-140419
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PROTAC Linkers
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Cancer
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t-Boc-Aminooxy-PEG12-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140613
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PROTAC Linkers
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Cancer
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Boc-PEG4-sulfone-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140420
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PROTAC Linkers
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Cancer
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Boc-Aminooxy-PEG4-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-138494
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PROTAC Linkers
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Cancer
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Boc-NH-PEG12-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140336
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PROTAC Linkers
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Cancer
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C-NH-Boc-C-Bis-(C-PEG1-Boc) is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-41062
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- HY-W101889
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N-Boc-N'-xanthyl-L-glutamine
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Amino Acid Derivatives
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Others
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Boc-Gln(Xan)-OH (N-Boc-N'-xanthyl-L-glutamine) is an amino acid derivative with a Boc protecting group, which can be used to synthesize peptides with antigenic activity .
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- HY-140565
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PROTAC Linkers
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Cancer
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N-(Azido-PEG3)-N-Boc-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG3)-N-Boc-PEG4-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-140562
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PROTAC Linkers
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Cancer
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N-(Azido-PEG2)-N-Boc-PEG3-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG2)-N-Boc-PEG3-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-140563
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PROTAC Linkers
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Cancer
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N-(Azido-PEG2)-N-Boc-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG2)-N-Boc-PEG4-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-140567
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PROTAC Linkers
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Cancer
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N-(Azido-PEG4)-N-Boc-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG4)-N-Boc-PEG4-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-W091365
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N-Boc-N'-xanthyl-L-asparagine
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Amino Acid Derivatives
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Others
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Boc-Asn(Xan)-OH (N-Boc-N'-xanthyl-L-asparagine) is an amino acid derivative with a Boc protecting group, which can be used to synthesize locust fat growth hormone .
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- HY-160124
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FGFR
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Cancer
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Infigratinib-Boc is a derivative of Infigratinib containing a Boc (t-Butyloxy carbonyl) group. Infigratinib is an ATP-competitive pan-FGFR inhibitor .
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- HY-79096S2
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- HY-79096S1
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- HY-79096S
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- HY-140568
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N-(Hydroxy-PEG3)-N-Boc-PEG4-t-butyl ester
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PROTAC Linkers
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Cancer
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N-(Hydroxy-PEG3)-N-Boc-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140566
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PROTAC Linkers
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Cancer
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N-Azido-PEG4-N-Boc-N-PEG3-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-Azido-PEG4-N-Boc-N-PEG3-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-168276
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PROTAC Linkers
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Cancer
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Boc-Nonanol is a PROTAC linker. Boc-Nonanol can be used in the synthesis of PROTAC TRIB2 degrader-1 (HY-168274) .
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- HY-161931
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- HY-141395
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ADC Linker
PROTAC Linkers
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Cancer
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m-PEG4-Boc is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . m-PEG4-Boc is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-13229R
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Caspase
Apoptosis
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Cancer
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BOC-D-FMK (Standard) is the analytical standard of BOC-D-FMK. This product is intended for research and analytical applications. Boc-D-FMK is a cell-permeable, irreversible and broad spectrum caspase inhibitor. Boc-D-FMK inhibits apoptosis stimulated by TNF-α with an IC50 of 39 μM.
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- HY-W088100
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N-Boc-N'-trityl-D-asparagine; Boc-D-Asn(Trt)-OH
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Amino Acid Derivatives
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Cancer
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Boc-N-gamma-trityl-D-asparagin (N-Boc-N'-trityl-D-asparagine) is an amino acid derivative with a Boc protecting group, which can be used to synthesize metastasis-inhibiting or tumor growth-inhibiting metastasis-inhibiting MS derivatives .
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- HY-W584534
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Ligands for E3 Ligase
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Cancer
|
|
VH032-CH2-Boc is a Boc-modified VH032 (HY-120217) that serves as a ligand for VHL and recruits von Hippel-Lindau (VHL) proteins. VH032-CH2-Boc will remove the protecting group under acidic conditions and be directly used in PROTAC molecule synthesis. VH032-CH2-Boc is a key intermediate in the synthesis of PROTAC based on VHL ligand.
|
-
- HY-W584535
-
|
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
VH032-C3-Boc is a Boc-modified VH032 (HY-120217) that serves as a ligand for VHL and recruits von Hippel-Lindau (VHL) proteins. VH032-C3-Boc will remove the protective group under acidic conditions and be directly used for PROTAC molecular synthesis. VH032-C3-Boc is a key intermediate for the synthesis of PROTACs based on VHL ligands.
|
-
- HY-140232A
-
|
Boc-NH-PEG1000-Amine
|
Biochemical Assay Reagents
|
Others
|
|
BOC-NH-PEG1000-NH2 (Boc-NH-PEG1000-Amine) is a linear hetero-bifunctional PEG product with one Boc-protected amine and one amino group. BOC-NH-PEG1000-NH2 is an important cross-linker with PEG chains .
|
-
- HY-W784624
-
|
|
Drug Intermediate
|
Others
|
|
Boc‑PNA‑C (Z)‑OH is a cytosine-containing peptide nucleic acid monomer, in which the amino group and cytosine are protected by tert-butoxycarbonyl (Boc) and benzyloxycarbonyl groups, respectively. Boc‑PNA‑C (Z)‑OH can be used for the synthesis of peptide nucleic acids .
|
-
- HY-160513
-
|
|
DNA/RNA Synthesis
|
Others
|
|
Fmoc‑PNA‑Abasic(Boc)‑OH is a synthetic peptide nucleic acid modified with Fmoc and Boc protecting groups. Fmoc‑PNA‑Abasic(Boc)‑OH can be used in molecular biology research.
|
-
- HY-P11687
-
|
|
Drug Intermediate
|
Others
|
|
Fmoc-PNA-M(Boc)-OH is a peptide nucleic acid monomer with Fmoc and Boc protecting groups. Fmoc-PNA-M(Boc)-OH can be used for synthesis of peptide nucleic acid .
|
-
- HY-W344383
-
|
|
Ser/Thr Protease
|
Others
|
|
Boc-Phe-Ser-Arg-AMC is a trypsin peptide substrate containing a Boc protecting group. Boc-Phe-Ser-Arg-AMC can be degraded by trypsin, releasing AMC (HY-D0027) which has fluorescence activity. Boc-Phe-Ser-Arg-AMC can be used to assess the activity of trypsin .
|
-
- HY-P5834A
-
|
|
Caspase
Apoptosis
|
Inflammation/Immunology
|
|
Boc-AEVD-CHO TFA is a Caspase 8 inhibitor. Boc-AEVD-CHO TFA significantly increases the frequencies of Nocodazole (HY-13520) or methyl methane sulfonate (MMS) induced micronuclei (MN) and micronucleated binucleates (MNCB) in PBMC by inhibiting cell apoptosis. Boc-AEVD-CHO TFA can be used for immune and inflammatory diseases research .
|
-
- HY-P11367
-
|
|
Fluorescent Dye
Ser/Thr Protease
|
Infection
Metabolic Disease
|
|
Boc-Ala-Gly-Pro-Arg-AMC is a synthetic fluorescent substrate, widely used for the detection of protease activity. Boc-Ala-Gly-Pro-Arg-AMC can be used to detect the activity of serine proteases and the oligopeptide enzyme B of Trypanosoma brucei .
|
-
- HY-403689
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Fmoc-PNA-J(Boc)-OH is a nucleobase-modified PNA monomer (2-aminopyridine PNA monomer M) with Fmoc and Boc protecting groups, used for solid-phase synthesis of PNAs that form stable Hoogsteen triple helices with double-stranded RNA at physiologically relevant conditions .
|
-
- HY-W154175
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Boc-DODA is a linker containing a Boc-protected amino group and a terminal amine. The Boc group can be deprotected under mild acidic conditions to form the free amine. The terminal amine is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.
|
-
- HY-181496
-
|
|
Epigenetic Reader Domain
|
Cancer
|
|
(S)-JQ-35-Boc is a BRD4 ligand. (S)-JQ-35-Boc can be used to synthesize BRD4 degrader RAJQ14 (HY-181495). RAJQ14 can be used for cancer research .
|
-
- HY-169775
-
|
|
Drug Intermediate
|
Cancer
|
|
Doxorubicin-Boc (Dox-Boc) is a drug intermediate that can be used for the synthesis of Adamantane (HY-N2427)-Doxorubicin (HY-15142A) produrg .
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-W008034
-
|
Fmoc-L-Trp(Boc)-OH
|
Biochemical Assay Reagents
|
|
Fmoc-Trp(Boc)-OH (Fmoc-L-Trp(Boc)-OH) is an amino acid derivative with protective groups. Fmoc-Trp(Boc)-OH can self-assemble into stable and pH-responsive spherical nanoparticles, which can load and release bioactive molecules, with good biocompatibility and high cell uptake rate. Fmoc-Trp(Boc)-OH can be used in research on drug delivery .
|
-
- HY-40020
-
|
|
Biochemical Assay Reagents
|
|
1-Boc-3-piperidone is a Boc-protected piperidone derivative. 1-Boc-3-piperidone is an important intermediate in organic synthesis. 1-Boc-3-piperidone can be used to study compounds related to inflammatory skin diseases (such as atopic dermatitis), lymphoma, and other diseases .
|
-
- HY-40114
-
|
|
Biochemical Assay Reagents
|
|
Boc-L-proline is an amino acid derivative. As an important intermediate in organic synthesis, Boc-L-proline can be used for peptide synthesis .
|
-
- HY-W008325
-
|
|
Biochemical Assay Reagents
|
|
Boc-L-Dap-OH is a Boc-protected derivative of L-2,3-diaminopropionic acid. Boc-L-Dap-OH is an important chiral amino acid derivative. Boc-L-Dap-OH can be generated via the Hofmann rearrangement of Boc-L-asparagine. Boc-L-Dap-OH serves as a starting material for the preparation of BIM analogs .
|
-
- HY-W007729
-
|
|
Biochemical Assay Reagents
|
|
Boc-L-Alaninol is a Boc-protected chiral amino alcohol. Boc-L-Alaninol can be used in the synthesis of optically active bipyridine-containing polymers .
|
-
- HY-40091
-
|
1-Boc-3-aminopyrrolidine
|
Biochemical Assay Reagents
|
|
1-Boc-3-Aminopyrrolidine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W009229
-
|
|
Biochemical Assay Reagents
|
|
Boc-Glu(OtBu)-OH is a protected glutamic acid derivative with two protecting groups: Boc- and OTBu. Boc-Glu(OtBu)-OH can be used in the study of peptide compound synthesis .
|
-
- HY-W007743
-
|
Boc-L-pipecolic acid
|
Biochemical Assay Reagents
|
|
Boc-Pip-OH (Boc-L-pipecolic acid) is a t-butyloxycarbonylamino acid. Boc-Pip-OH can serve as a radical precursor .
|
-
- HY-79096
-
|
|
Biochemical Assay Reagents
|
|
Boc-L-phenylalanine is a Boc-protected L-phenylalanine that can be used in the synthesis of other active compounds. Boc-L-phenylalanine is also a capping agent .
|
-
- HY-40021
-
|
N-Boc-2-Piperidone
|
Biochemical Assay Reagents
|
|
1-Boc-2-piperidone is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W009673
-
|
N-Boc-L-pyroglutamic acid
|
Biochemical Assay Reagents
|
|
Boc-Pyr-OH is a Boc-protected pyroglutamic acid derivative. Boc-Pyr-OH stabilizes the amino group of pyroglutamic acid through the Boc protecting group, preventing unwanted reactions during peptide synthesis. Boc-Pyr-OH can be used in the research of thyrotropin-releasing hormone (TRH) synthesis .
|
-
- HY-60218
-
|
|
Biochemical Assay Reagents
|
|
1-Boc-3-(hydroxymethyl)pyrrolidine is an intermediate. 1-Boc-3-(hydroxymethyl)pyrrolidine can be used to synthesize a FGFR1/2/3/4 inhibitor (Compound 2). 1-Boc-3-(hydroxymethyl)pyrrolidine can be used in cancer research .
|
-
- HY-140232A
-
|
Boc-NH-PEG1000-Amine
|
Biochemical Assay Reagents
|
|
BOC-NH-PEG1000-NH2 (Boc-NH-PEG1000-Amine) is a linear hetero-bifunctional PEG product with one Boc-protected amine and one amino group. BOC-NH-PEG1000-NH2 is an important cross-linker with PEG chains .
|
| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P1449
-
|
|
ADC Linker
|
Cancer
|
|
Boc-Gly-Gly-Phe-Gly-OH, a self-assembly of N- and C-protected tetrapeptide, is a protease cleavable linker used for the antibody-drug conjugate (ADC).
|
-
- HY-115391
-
|
Boc-Leu-Arg-Arg-AMC
|
Biochemical Assay Reagents
|
Others
|
|
Boc-LRR-AMC (Boc-Leu-Arg-Arg-AMC) is a fluorogenic substrate, which can be utilized for detecting the trypsin-like activity of the 26S proteasome or the 20S proteasome core .
|
-
- HY-P1795
-
|
|
Formyl Peptide Receptor (FPR)
|
Inflammation/Immunology
|
|
Boc-dPhe-Leu-dPhe-Leu-Phe (Boc-fLfLF) is a selective N-formyl peptide receptor1 (FPR1) antagonist. Boc-dPhe-Leu-dPhe-Leu-Phe inhibits fMIFL(HY-P0224)-induced NADPH oxidase activity. Boc-dPhe-Leu-dPhe-Leu-Phe can be used for the study of inflammation .
|
-
- HY-41121
-
|
Boc-Ala-OH
|
Amino Acid Derivatives
|
Cancer
|
|
Boc-L-Ala-OH (Boc-Ala-OH) is a single N-protected amino acid ligand and a protected L-alanine derivative. Boc-L-Ala-OH promotes Pd (II)-catalyzed enantioselective C-H alkenylation and kinetic resolution. Boc-L-Ala-OH serves as a coupling reagent for the synthesis of liver-targeted glycogen phosphorylase inhibitors and P6A metabolites, and also acts as a negative control in synthesis studies of betulinic acid amino acid esters. Boc-L-Ala-OH is applicable to research on epidermoid squamous cell carcinoma .
|
-
- HY-P2237
-
-
- HY-P2008
-
|
IEGR-AMC
|
Factor Xa
|
Cardiovascular Disease
|
|
Boc-Ile-Glu-Gly-Arg-AMC (IEGR-AMC) is an activated factor X (FXa) specific fluorogenic peptide substrate used for Factor VIII determination .
|
-
- HY-P2355
-
|
Boc2; Boc-Phe-dLeu-Phe-dLeu-Phe
|
Formyl Peptide Receptor (FPR)
|
Inflammation/Immunology
|
|
BOC-FlFlF (Boc-Phe-dLeu-Phe-dLeu-Phe) is a selective FPR1 antagonist. Boc-FlFlF has an apparent dissociation constant (KD) of 230 nM as determined by the intracellular calcium mobilization assay. Boc-FlFlF can be used for the study of inflammation .
|
-
- HY-P4548
-
|
Boc-RVRR-AMC
|
Furin
|
Others
|
|
Boc-Arg-Val-Arg-Arg-AMC hydrochloride (Boc-RVRR-AMC) is a synthetic fluorogenic substrate that is efficiently cleaved by furin .
|
-
- HY-W101935
-
|
N-Boc-D-arginine hydrochloride
|
Amino Acid Derivatives
|
Others
|
|
N-Boc-D-Arg hydrochloride (N-Boc-D-arginine hydrochloride) is an amino acid derivative with a Boc protecting group, which can be used to synthesize desmopressin with the effects of improving nocturia, urinary incontinence and enuresis .
|
-
- HY-W077219
-
|
Boc-Arg(Mtr)-OH
|
Amino Acid Derivatives
|
Others
|
|
Boc-L-Arg(Mtr)-OH (Boc-Arg(Mtr)-OH) is an amino acid derivative with a Boc protecting group, which can be used to synthesize peptides with antithrombotic activity .
|
-
- HY-W011321
-
-
- HY-W008919
-
|
N-Alpha,N-epsilon-di-Boc-L-lysine 4-nitrophenyl ester
|
Amino Acid Derivatives
|
Others
|
|
Boc-Lys(Boc)-Onp (N-Alpha,N-epsilon-di-Boc-L-lysine 4-nitrophenyl ester) is a lysine with a Boc protecting group. Boc-Lys(Boc)-Onp was used as a substrate for a catalyst model to study its enzymatic hydrolysis reaction catalyzed by a copper(II) complex .
|
-
- HY-W101495
-
|
N-Boc-L-leucine monohydrate
|
Amino Acid Derivatives
|
Others
|
|
Boc-Leu-OH hydrate (N-Boc-L-leucine monohydrate) is an amino acid derivative with a Boc protecting group, which can be used to synthesize L-prolyl-L-leucyl-glycinamide peptide, a peptide mimetic with dopamine receptor modulatory activity .
|
-
- HY-W002299
-
|
Boc-D-Leu-OH hydrate
|
Amino Acid Derivatives
|
Neurological Disease
|
|
Boc-D-Leucine monohydrate (Boc-D-Leu-OH hydrate) is an N-Boc-protected form of D-Leucine. D-Leucine is an unnatural isomer of L-Leucine that acts as an auto-inhibitor of lactic streptococci. D-Leucine shows potent anti-seizure effect .
|
-
- HY-W008633
-
-
- HY-P4458
-
|
|
Ser/Thr Protease
|
Cancer
|
|
Boc-QAR-pNA is a chromogenic substrate of trypsin. Boc-QAR-pNA can be used to test trypsin activity .
|
-
- HY-W013781
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Boc-Glu(OBzl)-OH (Compound 9) is a glutamic acid derivative commonly used in Boc SPPS. Glutamic acid residues increase the hydrophilicity of the polypeptide and play an important structural and receptor binding role .
|
-
- HY-41912B
-
|
Boc-D-Nle-OH; N-Boc-D-norleucine
|
Amino Acid Derivatives
|
Others
|
|
Boc-D-norleucine (Boc-D-Nle-OH) is a leucine derivative that can be used for peptide synthesis .
|
-
- HY-41631
-
|
(S)-Ethyl-N-Boc-pyroglutamate
|
Amino Acid Derivatives
Drug Intermediate
|
Others
|
|
Boc-Pyr-Oet ((S)-Ethyl-N-Boc-pyroglutamate) is a derivative of L-Pyroglutamic acid (HY-76082). Boc-Pyr-Oet can be used for the synthesis of agents or other compounds.
|
-
- HY-W003605
-
|
N-Boc-D-pyroglutamic acid ethyl ester
|
Biochemical Assay Reagents
|
Others
|
|
Boc-D-Pyr-Oet (N-Boc-D-pyroglutamic acid ethyl ester) is used as a biochemical assay reagent .
|
-
- HY-W010835
-
|
Boc-S-trityl-D-cysteine
|
Amino Acid Derivatives
|
Others
|
|
Boc-D-Cys(Trt)-OH (Boc-S-trityl-D-cysteine) is an amino acid derivative with a Boc protecting group, which can be used to synthesize the bicyclic depsipeptide histone deacetylase inhibitor spirocysteine .
|
-
- HY-W014692
-
|
N-t-Boc-amino-D-alanine; Boc-D-Dap-OH
|
Amino Acid Derivatives
|
Others
|
|
Boc-D-2,3-diaminopropionic acid (N-t-Boc-amino-D-alanine) is an amino acid derivative with a Boc protecting group, which can be used to synthesize a potent NMDA receptor glycine site agonist with GluN2 subunit-specific activity .
|
-
- HY-P2355A
-
|
Boc2 TFA; Boc-Phe-dLeu-Phe-dLeu-Phe TFA
|
Formyl Peptide Receptor (FPR)
|
Inflammation/Immunology
|
|
BOC-FlFlF (TFA) (Boc-Phe-dLeu-Phe-dLeu-Phe (TFA)) is a selective FPR1 antagonist. BOC-FlFlF has an apparent dissociation constant (KD) of 230 nM as determined by the intracellular calcium mobilization assay. BOC-FlFlF can be used for the study of inflammation .
|
-
- HY-W753820A
-
|
Boc-Leu-Arg-Arg-AMC TFA
|
Biochemical Assay Reagents
|
Others
|
|
Boc-LRR-AMC TFA (Boc-Leu-Arg-Arg-AMC TFA) is the TFA salt form of Boc-LRR-AMC (HY-115391). Boc-LRR-AMC TFA is a fluorogenic substrate, which can be utilized for detecting the trypsin-like activity of the 26S proteasome or the 20S proteasome core .
|
-
- HY-W003605A
-
|
|
Amino Acid Derivatives
|
Others
|
|
1-Boc-DL-Pyroglutamic acid ethyl ester is a Boc-protected Pyroglutamic acid derivative, can be used for the synthesis of agents or other compounds .
|
-
- HY-P4716
-
|
|
Amino Acid Derivatives
|
Inflammation/Immunology
|
|
Boc-D-Trp(For)-OH, containing the amino acid tryptophan, is synthesized by the ammonolysis of Boc-protected D-alanine, followed by cyclization to form a dipeptide with ninhydrin. Boc-D-Trp(For)-OH has pharmacological properties, including inhibition of growth hormone release, induction of sleep and antiinflammatory .
|
-
- HY-400312
-
-
- HY-P5834
-
-
- HY-P2669
-
-
- HY-P10060
-
-
- HY-P2715
-
-
- HY-W048332
-
-
- HY-W129194
-
-
- HY-W101889
-
|
N-Boc-N'-xanthyl-L-glutamine
|
Amino Acid Derivatives
|
Others
|
|
Boc-Gln(Xan)-OH (N-Boc-N'-xanthyl-L-glutamine) is an amino acid derivative with a Boc protecting group, which can be used to synthesize peptides with antigenic activity .
|
-
- HY-W091365
-
|
N-Boc-N'-xanthyl-L-asparagine
|
Amino Acid Derivatives
|
Others
|
|
Boc-Asn(Xan)-OH (N-Boc-N'-xanthyl-L-asparagine) is an amino acid derivative with a Boc protecting group, which can be used to synthesize locust fat growth hormone .
|
-
- HY-W088100
-
|
N-Boc-N'-trityl-D-asparagine; Boc-D-Asn(Trt)-OH
|
Amino Acid Derivatives
|
Cancer
|
|
Boc-N-gamma-trityl-D-asparagin (N-Boc-N'-trityl-D-asparagine) is an amino acid derivative with a Boc protecting group, which can be used to synthesize metastasis-inhibiting or tumor growth-inhibiting metastasis-inhibiting MS derivatives .
|
-
- HY-W784624
-
|
|
Drug Intermediate
|
Others
|
|
Boc‑PNA‑C (Z)‑OH is a cytosine-containing peptide nucleic acid monomer, in which the amino group and cytosine are protected by tert-butoxycarbonyl (Boc) and benzyloxycarbonyl groups, respectively. Boc‑PNA‑C (Z)‑OH can be used for the synthesis of peptide nucleic acids .
|
-
- HY-160513
-
|
|
DNA/RNA Synthesis
|
Others
|
|
Fmoc‑PNA‑Abasic(Boc)‑OH is a synthetic peptide nucleic acid modified with Fmoc and Boc protecting groups. Fmoc‑PNA‑Abasic(Boc)‑OH can be used in molecular biology research.
|
-
- HY-P11687
-
|
|
Drug Intermediate
|
Others
|
|
Fmoc-PNA-M(Boc)-OH is a peptide nucleic acid monomer with Fmoc and Boc protecting groups. Fmoc-PNA-M(Boc)-OH can be used for synthesis of peptide nucleic acid .
|
-
- HY-W344383
-
|
|
Ser/Thr Protease
|
Others
|
|
Boc-Phe-Ser-Arg-AMC is a trypsin peptide substrate containing a Boc protecting group. Boc-Phe-Ser-Arg-AMC can be degraded by trypsin, releasing AMC (HY-D0027) which has fluorescence activity. Boc-Phe-Ser-Arg-AMC can be used to assess the activity of trypsin .
|
-
- HY-P5834A
-
|
|
Caspase
Apoptosis
|
Inflammation/Immunology
|
|
Boc-AEVD-CHO TFA is a Caspase 8 inhibitor. Boc-AEVD-CHO TFA significantly increases the frequencies of Nocodazole (HY-13520) or methyl methane sulfonate (MMS) induced micronuclei (MN) and micronucleated binucleates (MNCB) in PBMC by inhibiting cell apoptosis. Boc-AEVD-CHO TFA can be used for immune and inflammatory diseases research .
|
-
- HY-P10059
-
|
|
Peptides
|
Others
|
|
Boc-Val-Gly-Arg-βNA is a colorimetric substrate for plasminogen activator .
|
-
- HY-P11367
-
|
|
Fluorescent Dye
Ser/Thr Protease
|
Infection
Metabolic Disease
|
|
Boc-Ala-Gly-Pro-Arg-AMC is a synthetic fluorescent substrate, widely used for the detection of protease activity. Boc-Ala-Gly-Pro-Arg-AMC can be used to detect the activity of serine proteases and the oligopeptide enzyme B of Trypanosoma brucei .
|
-
- HY-403689
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Fmoc-PNA-J(Boc)-OH is a nucleobase-modified PNA monomer (2-aminopyridine PNA monomer M) with Fmoc and Boc protecting groups, used for solid-phase synthesis of PNAs that form stable Hoogsteen triple helices with double-stranded RNA at physiologically relevant conditions .
|
-
- HY-W801296
-
|
Boc-L-Pyroglutamicacidtert-butylester
|
Peptides
|
Others
|
|
Boc-Pyr-OtBu (Boc-L-Pyroglutamicacidtert-butylester) is a peptide intermediate and can be used in peptide synthesis.
|
-
- HY-W351592
-
|
Boc-S-acetamidomethyl-L-penicillamine
|
Peptides
|
Others
|
|
Boc-Pen(Acm)-OH (Boc-S-acetamidomethyl-L-penicillamine) is a peptide intermediate and can be used in peptide synthesis.
|
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| Source |
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| Tag |
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* This product has been "discontinued".
Optimized version of product available:
|
| Cat. No. |
Product Name |
Chemical Structure |
-
- HY-79096S2
-
|
|
|
BOC-L-phenylalanine-d8 is the deuterium labeled BOC-L-phenylalanine (HY-79096). Boc-L-phenylalanine is a Boc-protected L-phenylalanine that can be used in the synthesis of other active compounds. Boc-L-phenylalanine is also a capping agent .
|
-
-
- HY-79096S1
-
|
|
|
BOC-L-phenylalanine-d5 is the deuterium labeled BOC-L-phenylalanine (HY-79096). Boc-L-phenylalanine is a Boc-protected L-phenylalanine that can be used in the synthesis of other active compounds. Boc-L-phenylalanine is also a capping agent .
|
-
-
- HY-79096S
-
|
|
|
BOC-L-Phenylalanine- 13C is a 13C-labeled BOC-L-Phenylalanine (HY-79096). Boc-L-phenylalanine is a Boc-protected L-phenylalanine that can be used in the synthesis of other active compounds. Boc-L-phenylalanine is also a capping agent .
|
-
| Cat. No. |
Product Name |
|
Classification |
-
- HY-140565
-
|
|
|
Azide
PROTAC Synthesis
|
|
N-(Azido-PEG3)-N-Boc-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG3)-N-Boc-PEG4-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140562
-
|
|
|
PROTAC Synthesis
Azide
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N-(Azido-PEG2)-N-Boc-PEG3-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG2)-N-Boc-PEG3-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-140563
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PROTAC Synthesis
Azide
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N-(Azido-PEG2)-N-Boc-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG2)-N-Boc-PEG4-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-140567
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Azide
PROTAC Synthesis
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N-(Azido-PEG4)-N-Boc-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG4)-N-Boc-PEG4-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-140566
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Azide
PROTAC Synthesis
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N-Azido-PEG4-N-Boc-N-PEG3-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-Azido-PEG4-N-Boc-N-PEG3-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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