N-Boc-8-amino-octanoic acid
Based on 1 Customer Validation
N-Boc-8-amino-octanoic acid (Boc-8-aminooctanoic acid) can be used as a PROTAC linker in the synthesis of PROTACs. N-Boc-8-amino-octanoic acid is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.
For research use only. We do not sell to patients.
- Purity : 98.0%
- CAS No.: 30100-16-4
- Formula: C13H25NO4
- Molecular Weight:259.34
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Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
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Biological Activity
Description
Chemical Information
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CAS No. 30100-16-4
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Appearance Solid
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Molecular Weight 259.34
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Formula C13H25NO4
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Color White to off-white
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SMILES
O=C(O)CCCCCCCNC(OC(C)(C)C)=O
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Synonyms
Boc-8-aminooctanoic acid
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
In Vitro:
DMSO : 50 mg/mL (192.80 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (238 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.8559 mL | 19.2797 mL | 38.5594 mL | 96.3986 mL |
| 5 mM | 0.7712 mL | 3.8559 mL | 7.7119 mL | 19.2797 mL | |
| 10 mM | 0.3856 mL | 1.9280 mL | 3.8559 mL | 9.6399 mL | |
| 15 mM | 0.2571 mL | 1.2853 mL | 2.5706 mL | 6.4266 mL | |
| 20 mM | 0.1928 mL | 0.9640 mL | 1.9280 mL | 4.8199 mL | |
| 25 mM | 0.1542 mL | 0.7712 mL | 1.5424 mL | 3.8559 mL | |
| 30 mM | 0.1285 mL | 0.6427 mL | 1.2853 mL | 3.2133 mL | |
| 40 mM | 0.0964 mL | 0.4820 mL | 0.9640 mL | 2.4100 mL | |
| 50 mM | 0.0771 mL | 0.3856 mL | 0.7712 mL | 1.9280 mL | |
| 60 mM | 0.0643 mL | 0.3213 mL | 0.6427 mL | 1.6066 mL | |
| 80 mM | 0.0482 mL | 0.2410 mL | 0.4820 mL | 1.2050 mL | |
| 100 mM | 0.0386 mL | 0.1928 mL | 0.3856 mL | 0.9640 mL |
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