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Cat. No.: HY-181496

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(S)-JQ-35-Boc

(S)-JQ-35-Boc is a derivative of (S)-JQ-35 (HY-117286) and also a BRD4 inhibitor. (S)-JQ-35-Boc can be used in studies related to PROTAC synthesis, such as serving as the target protein ligand for RAJQ14 (HY-181495).

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 1950635-21-8
화학식: C₃₁H₄₀ClN₇O₃S
분자량:626.21

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (277 KB)

(S)-JQ-35-Boc Chemical Structure

CAS No.: 1950635-21-8

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

IC₅₀ & Target^[1]

BRD4

All Epigenetic Reader Domain Isoforms :

In Vitro

(S)-JQ-35-Boc serves as a target protein ligand for RAJQ14 (HY-181495). RAJQ14 is a BRD4-targeted PROTAC CAP-TAC degrader that is applicable to cancer-related research^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1950635-21-8
분자량 626.21
화학식 C₃₁H₄₀ClN₇O₃S
SMILES

O=C(NCCCN1CCN(C(OC(C)(C)C)=O)CC1)C[C@H]2C3=NN=C(C)N3C4=C(C(C)=C(C)S4)C(C5=CC=C(Cl)C=C5)=N2
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (277 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Song C, et al. Proteasome Cap Targeting Chimeras for Ubiquitination-Independent Targeted Protein Degradation. Angewandte Chemie (International ed. in English). 2026 Feb 23;65(9):e20039. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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Other size

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Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References

상품명:
Cat. No.:
수량:
MCE Japan Authorized Agent:

상품명:
CAS No.:
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(S)-JQ-35-Boc

All Epigenetic Reader Domain Isoforms