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  2. Boc-Leu-Gly-Arg-AMC

Boc-Leu-Gly-Arg-AMC 

Cat. No.: HY-P2237
Handling Instructions

Boc-Leu-Gly-Arg-AMC is a fluorogenic AMC substrate for the convertases. Boc-Leu-Gly-Arg-AMC can be used in enzymatic assays.

For research use only. We do not sell to patients.

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Boc-Leu-Gly-Arg-AMC Chemical Structure

Boc-Leu-Gly-Arg-AMC Chemical Structure

CAS No. : 65147-09-3

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Description

Boc-Leu-Gly-Arg-AMC is a fluorogenic AMC substrate for the convertases. Boc-Leu-Gly-Arg-AMC can be used in enzymatic assays[1][2].

In Vitro

To demonstrate the presence in the abdominal gland of proteolytic enzymes capable of generating Sodefrin, an enzymatic assay was developed using Boc-Leu-Gly-Arg-AMC as synthetic substrate. A crude extract of the abdominal gland hydrolyzed Boc-Leu-Gly-Arg-AMC to liberate 7-amino-4- methylcoumarin, suggesting that enzymes that generate sodefrin from its precursor molecule are present in the gland. The activity in the extract for cleaving Boc-Leu-Gly-Arg-AMC is optimal at pH 9.0 and 45 ℃[1].

Molecular Weight

601.69

Formula

C₂₉H₄₃N₇O₇

CAS No.

65147-09-3

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

Boc-Leu-Gly-Arg-AMCOthersSodefrinabdominalC-terminalserineproteasefluorogenicAMCconvertasesInhibitorinhibitorinhibit

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Boc-Leu-Gly-Arg-AMC
Cat. No.:
HY-P2237
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