Boc-Glu(OtBu)-OH
Based on 1 Customer Validation
Boc-Glu (OtBu)-OH is a glutamic acid-derived protected amino acid with its N-terminal amino group protected by tert-butyloxycarbonyl (Boc) and side-chain carboxyl group protected by tert-butyl ester (OtBu), serving as an orthogonally protected building block for polypeptide synthesis. Boc-Glu (OtBu)-OH is applicable to research on the synthesis of peptide compounds.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 13726-84-6
- Formula: C14H25NO6
- Molecular Weight:303.35
-
Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Boc-Glu(OtBu)-OH (0°C to room temperature, 30 min) readily undergoes intramolecular cyclization to form tert-butyl pyroglutamate upon deprotection of Boc with 4 M HCl/dioxane[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 13726-84-6
-
Appearance Solid
-
Molecular Weight 303.35
-
Formula C14H25NO6
-
Color White to off-white
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 200 mg/mL (659.30 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (278 KB)
-
SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.2965 mL | 16.4826 mL | 32.9652 mL | 82.4131 mL |
| 5 mM | 0.6593 mL | 3.2965 mL | 6.5930 mL | 16.4826 mL | |
| 10 mM | 0.3297 mL | 1.6483 mL | 3.2965 mL | 8.2413 mL | |
| 15 mM | 0.2198 mL | 1.0988 mL | 2.1977 mL | 5.4942 mL | |
| 20 mM | 0.1648 mL | 0.8241 mL | 1.6483 mL | 4.1207 mL | |
| 25 mM | 0.1319 mL | 0.6593 mL | 1.3186 mL | 3.2965 mL | |
| 30 mM | 0.1099 mL | 0.5494 mL | 1.0988 mL | 2.7471 mL | |
| 40 mM | 0.0824 mL | 0.4121 mL | 0.8241 mL | 2.0603 mL | |
| 50 mM | 0.0659 mL | 0.3297 mL | 0.6593 mL | 1.6483 mL | |
| 60 mM | 0.0549 mL | 0.2747 mL | 0.5494 mL | 1.3736 mL | |
| 80 mM | 0.0412 mL | 0.2060 mL | 0.4121 mL | 1.0302 mL | |
| 100 mM | 0.0330 mL | 0.1648 mL | 0.3297 mL | 0.8241 mL |