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Isoforms Recommended: CYP3
Results for "

CYP3A5

" in MedChemExpress (MCE) Product Catalog:

12

Inhibitors & Agonists

3

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-18642
    CYP3cide

    PF-4981517

    		 Cytochrome P450 Others
    CYP3cide (PF-4981517) is a potent, selective and time-dependent inhibitor of cytochrome P4503A4 (CYP3A4). The IC50 values for Midazolam 1’-hydroxylase activity are 0.03 μM, 17 μM, and 71 μM for CYP3A4, CYP3A5, and CYP3A7, respectively. CYP3cide can be used to distinguish the contributions of CYP3A4 versus CYP3A5 on agent metabolism .
    CYP3cide
  • HY-135810
    Cletoquine

    Desethylhydroxychloroquine

    		 Influenza Virus Parasite Infection Inflammation/Immunology
    Cletoquine (Desethylhydroxychloroquine) is a major active metabolite of Hydroxychloroquine. Cletoquine is produced in the liver by CYP2D6, CYP3A4, CYP3A5, and CYP2C8 isoenzymes. Cletoquine is also a Chloroquine derivative and has the ability to against the chikungunya virus (CHIKV). Cletoquine has antimalarial effects and has the potential for autoimmune diseases treatment .
    Cletoquine
  • HY-135810A
    Cletoquine oxalate

    Desethylhydroxychloroquine oxalate

    		 Influenza Virus Parasite Infection Inflammation/Immunology
    Cletoquine oxalate (Desethylhydroxychloroquine oxalate) is a major active metabolite of Hydroxychloroquine. Cletoquine oxalate is produced in the liver by CYP2D6, CYP3A4, CYP3A5, and CYP2C8 isoenzymes. Cletoquine oxalate is also a Chloroquine derivative and has the ability to against the chikungunya virus (CHIKV). Cletoquine oxalate has antimalarial effects and has the potential for autoimmune diseases treatment .
    Cletoquine oxalate
  • HY-RS03473
    CYP3A5 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    CYP3A5 Human Pre-designed siRNA Set A contains three designed siRNAs for CYP3A5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    CYP3A5 Human Pre-designed siRNA Set A
    CYP3A5 Human Pre-designed siRNA Set A
  • HY-13600S1
    Clobetasol propionate-d5

    		Isotope-Labeled Compounds Cytochrome P450 Inflammation/Immunology
    Clobetasol propionate-d5 is a deuterium substitute of Clobetasol propionate. Clobetasol propionate is a potent, selective CYP3A5 inhibitor with a IC50 of 0.206 μM and has potential for use in the study of psoriasis and other skin diseases .
    Clobetasol propionate-d5
  • HY-13600
    Clobetasol propionate

    		Cytochrome P450 Inflammation/Immunology Endocrinology
    Clobetasol propionate is a potent and selective CYP3A5 inhibitor with an IC50 of 0.206 μM. Clobetasol propionate has no inhibiting on CYP3A4 or other major CYPs. Clobetasol propionate is a corticosteroid and has the potential for psoriasis and other dermatoses research .
    Clobetasol propionate
  • HY-13600R
    Clobetasol propionate (Standard)

    		Cytochrome P450 Inflammation/Immunology Endocrinology Cancer
    Clobetasol propionate (Standard) is the analytical standard of Clobetasol propionate. This product is intended for research and analytical applications. Clobetasol propionate is a potent and selective CYP3A5 inhibitor with an IC50 of 0.206 μM. Clobetasol propionate has no inhibiting on CYP3A4 or other major CYPs. Clobetasol propionate is a corticosteroid and has the potential for psoriasis and other dermatoses research .
    Clobetasol propionate (Standard)
  • HY-113031
    16a-Hydroxydehydroisoandrosterone

    16α-Hydroxy-DHEA; 16α-OH-DHEA; 16α-hydroxy DHEA

    		 Others Endocrinology
    16α-hydroxy Dehydroepiandrosterone is a metabolite of the endogenous steroid hormone dehydroepiandrosterone. 16α-hydroxy Dehydroepiandrosterone is formed from dehydroepiandrosterone via 16-hydroxylation by the cytochrome P450 (CYP) isoforms CYP3A4 and CYP3A5 in adult human liver microsomes, as well as by fetal recombinant CYP3A7. It is a precursor to fetal estrogens, including estriol.
    16a-Hydroxydehydroisoandrosterone
  • HY-135810S
    Cletoquine-d4

    Desethylhydroxychloroquine-d4

    		 Isotope-Labeled Compounds Influenza Virus Parasite Infection Inflammation/Immunology
    Cletoquine-d4 is deuterium labeled Cletoquine. Cletoquine (Desethylhydroxychloroquine) is a major active metabolite of Hydroxychloroquine. Cletoquine is produced in the liver by CYP2D6, CYP3A4, CYP3A5, and CYP2C8 isoenzymes. Cletoquine is also a Chloroquine derivative and has the ability to against the chikungunya virus (CHIKV). Cletoquine has antimalarial effects and has the potential for autoimmune diseases treatment[1][2].
    Cletoquine-d4
  • HY-135810S1
    Cletoquine-d4-1

    Desethylhydroxychloroquine-d4-1

    		 Isotope-Labeled Compounds Influenza Virus Parasite Infection Inflammation/Immunology
    Cletoquine-d4-1 is the deuterium labeled Cletoquine. Cletoquine (Desethylhydroxychloroquine) is a major active metabolite of Hydroxychloroquine. Cletoquine is produced in the liver by CYP2D6, CYP3A4, CYP3A5, and CYP2C8 isoenzymes. Cletoquine is also a Chloroquine derivative and has the ability to against the chikungunya virus (CHIKV). Cletoquine has antimalarial effects and has the potential for autoimmune diseases treatment[1][2].
    Cletoquine-d4-1
  • HY-145000
    N-Desalkyludenafil

    		Drug Metabolite Endocrinology
    N-Desalkyludenafil is a metabolite of Udenafil. Udenafil is a PDE5 inhibitor used for the research of the erectile dysfunction .
    N-Desalkyludenafil
  • HY-117605
    N-Desmethyl Sildenafil

    Desmethylsildenafil; UK-103,320

    		 Phosphodiesterase (PDE) Cardiovascular Disease
    N-Desmethyl Sildenafil (Desmethylsildenafil) is a major metabolite of Sildenafil. Sildenafil is a potent phosphodiesterase type 5 (PDE5) inhibitor .
    N-Desmethyl Sildenafil

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