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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
24 Results for "
CYP3A5
" in MedChemExpress (MCE) Product Catalog:
Products (24)
24 Results for "CYP3A5" in MCE Product Catalog:
1
1 Cited Publications
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Clobetasol propionate is a potent and selective CYP3A5 inhibitor with an IC50 of 0.206 μM. Clobetasol propionate has no inhibiting on CYP3A4 or other major CYPs. Clobetasol propionate is a corticosteroid and has the potential for psoriasis and other dermatoses research .
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Cat. No.: HY-18642
CAS No.: 1390637-82-7
Synonyms: PF-4981517
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CYP3cide (PF-4981517) is a potent, selective and time-dependent inhibitor of cytochrome P4503A4 (CYP3A4). The IC50 values for Midazolam 1’-hydroxylase activity are 0.03 μM, 17 μM, and 71 μM for CYP3A4, CYP3A5, and CYP3A7, respectively. CYP3cide can be used to distinguish the contributions of CYP3A4 versus CYP3A5 on agent metabolism .
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Cletoquine (Desethylhydroxychloroquine) is a major active metabolite of Hydroxychloroquine. Cletoquine is produced in the liver by CYP2D6, CYP3A4, CYP3A5, and CYP2C8 isoenzymes. Cletoquine is also a Chloroquine derivative and has the ability to against the chikungunya virus (CHIKV). Cletoquine has antimalarial effects and has the potential for autoimmune diseases treatment .
Cat. No.: HY-13600R
CAS No.: 25122-46-7
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Clobetasol propionate (Standard) is the analytical standard of Clobetasol propionate. This product is intended for research and analytical applications. Clobetasol propionate is a potent and selective CYP3A5 inhibitor with an IC50 of 0.206 μM. Clobetasol propionate has no inhibiting on CYP3A4 or other major CYPs. Clobetasol propionate is a corticosteroid and has the potential for psoriasis and other dermatoses research .
Synonyms: 16α-Hydroxy-DHEA; 16α-OH-DHEA; 16α-hydroxy DHEA
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16a-Hydroxydehydroisoandrosterone (16α-Hydroxy-DHEA) is a metabolite of the endogenous steroid hormone dehydroepiandrosterone. 16α-hydroxy Dehydroepiandrosterone is formed from dehydroepiandrosterone via 16-hydroxylation by the cytochrome P450 (CYP) isoforms CYP3A4 and CYP3A5 in adult human liver microsomes, as well as by fetal recombinant CYP3A7. It is a precursor to fetal estrogens, including estriol.
Synonyms: Desmethylsildenafil; UK-103,320
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N-Desmethyl Sildenafil (Desmethylsildenafil) is a major metabolite of Sildenafil. Sildenafil is a potent phosphodiesterase type 5 (PDE5) inhibitor .
Synonyms: BAY 1902607
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Filapixant (BAY 1902607) is an orally active and selective P2X3 receptor antagonist. Filapixant is applicable to the research of refractory chronic cough .
Cat. No.: HY-RS03473
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CYP3A5 Human Pre-designed siRNA Set A contains three designed siRNAs for CYP3A5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-E72104
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Human CYP3A5, Reductase+b5 refers to a near-physiological recombinant microsomal system co-expressed in insect cells, consisting of human cytochrome P450 3A5, NADPH-P450 oxidoreductase (CPR) and cytochrome b5. Human CYP3A5 is a human cytochrome P450 subtype belonging to the CYP3 family, which is predominantly expressed in human liver and intestine and metabolizes a variety of active compounds .
Cat. No.: HY-117605R
CAS No.: 139755-82-1
Synonyms: Desmethylsildenafil (Standard); UK-103,320 (Standard)
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N-Desmethyl Sildenafil (Standard) is the analytical standard of N-Desmethyl Sildenafil. This product is intended for research and analytical applications. N-Desmethyl Sildenafil (Desmethylsildenafil) is a major metabolite of Sildenafil. Sildenafil is a potent phosphodiesterase type 5 (PDE5) inhibitor .
Synonyms: Desethylhydroxychloroquine oxalate
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Cletoquine oxalate (Desethylhydroxychloroquine oxalate) is a major active metabolite of Hydroxychloroquine. Cletoquine oxalate is produced in the liver by CYP2D6, CYP3A4, CYP3A5, and CYP2C8 isoenzymes. Cletoquine oxalate is also a Chloroquine derivative and has the ability to against the chikungunya virus (CHIKV). Cletoquine oxalate has antimalarial effects and has the potential for autoimmune diseases treatment .
Cat. No.: HY-13600S1
CAS No.: 2280940-18-1
Cat. No.: HY-W740175
CAS No.: 3869-32-7
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6b-Hydroxy triamcinolone acetonide is a metabolite of the synthetic corticosteroid Triamcinolone acetonide (HY-B0636). 6b-Hydroxy triamcinolone acetonide is formed from triamcinolone acetonide by the cytochrome P450 (CYP) isoforms CYP3A4, CYP3A5, and CYP3A7.
Cat. No.: HY-W744187
CAS No.: 2280940-18-1
Cat. No.: HY-P705910
Purity: ≥ 90%, as determined by reducing SDS-PAGE .
Synonyms: CYP3A5; Flavoprotein-Linked Monooxygenase; Cytochrome P450 Family 3 Subfamily A Member 5; Aryl Hydrocarbon Hydroxylase; P450PCN3; Alternative Protein CYP3A5; CP35; Microsomal Monooxygenase; PCN3; Xenobiotic Monooxygenase; Cytochrome P450, Subfamily IIIA (
Cat. No.: HY-135810S
CAS No.: 1854126-47-8
Synonyms: Desethylhydroxychloroquine-d4
Cat. No.: HY-135810S1
CAS No.: 1216461-56-1
Synonyms: Desethylhydroxychloroquine-d4-1
Cat. No.: HY-W777442
CAS No.: 1216461-57-2
Cat. No.: HY-N17811
CAS No.: 910580-56-2
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
