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Cat. No.: HY-W744187

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Clobetasol 17-Propionate-d₅

Clobetasol 17-Propionate-d₅ is the deuterium labeled Clobetasol propionate (HY-13600). Clobetasol propionate is a potent and selective CYP3A5 inhibitor with an IC₅₀ of 0.206 μM. Clobetasol propionate has no inhibiting on CYP3A4 or other major CYPs. Clobetasol propionate is a corticosteroid and has the potential for psoriasis and other dermatoses research.

For research use only. We do not sell to patients.

CAS No.: 2280940-18-1
Formula: C₂₅H₂₇D₅ClFO₅
Molecular Weight:472.00

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (250 KB)

Clobetasol 17-Propionate-d₅ Chemical Structure

CAS No.: 2280940-18-1

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
- Application
Chemical Information
Purity & Documentation
Calculators
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Bioz

Biological Activity

Description

All Cytochrome P450 Isoforms :

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Application

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

CAS No. 2280940-18-1
Unlabeled Cas 25122-46-7
Molecular Weight 472.00
Formula C₂₅H₂₇D₅ClFO₅
SMILES

O=C1C=C[C@]2(C(CC[C@@]3([C@@]2([C@H](C[C@]4([C@]3(C[C@@H]([C@@]4(C(CCl)=O)OC(C([2H])(C([2H])([2H])[2H])[2H])=O)C)[H])C)O)F)[H])=C1)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.