2280940-18-1
Chemical Structure
Clobetasol 17-Propionate-d5
- CAS No.: 2280940-18-1
- Formula:C25H27D5ClFO5
- Molecular Weight:472.00
IUPAC Name: (8S,9R,10S,11S,13S,14S,16S,17R)-17-(2-chloroacetyl)-9-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl propanoate-d5
InChIKey: CBGUOGMQLZIXBE-BFHSNLKKSA-N
SMILES: O=C1C=C[C@]2(C(CC[C@@]3([C@@]2([C@H](C[C@]4([C@]3(C[C@@H]([C@@]4(C(CCl)=O)OC(C([2H])(C([2H])([2H])[2H])[2H])=O)C)[H])C)O)F)[H])=C1)C
Biological Activity: Clobetasol 17-Propionate-d5 is the deuterium labeled Clobetasol propionate (HY-13600). Clobetasol propionate is a potent and selective CYP3A5 inhibitor with an IC50 of 0.206 μM. Clobetasol propionate has no inhibiting on CYP3A4 or other major CYPs. Clobetasol propionate is a corticosteroid and has the potential for psoriasis and other dermatoses research[1][2][3].
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Clobetasol 17-Propionate-d5 | Clobetasol 17-Propionate-d5 is the deuterium labeled Clobetasol propionate (HY-13600). Clobetasol propionate is a potent and selective CYP3A5 inhibitor with an IC50 of 0.206 μM. Clobetasol propionate has no inhibiting on CYP3A4 or other major CYPs. Clobetasol propionate is a corticosteroid and has the potential for psoriasis and other dermatoses research. | |||||||||||||||||||||
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Clobetasol propionate (Standard) | 99.68% | Clobetasol propionate (Standard) is the analytical standard of Clobetasol propionate. This product is intended for research and analytical applications. Clobetasol propionate is a potent and selective CYP3A5 inhibitor with an IC50 of 0.206 μM. Clobetasol propionate has no inhibiting on CYP3A4 or other major CYPs. Clobetasol propionate is a corticosteroid and has the potential for psoriasis and other dermatoses research. | ||||||||||||||||||||
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Clobetasol propionate-d5 | Clobetasol propionate-d5 is a deuterium substitute of Clobetasol propionate. Clobetasol propionate is a potent, selective CYP3A5 inhibitor with a IC50 of 0.206 μM and has potential for use in the study of psoriasis and other skin diseases. | |||||||||||||||||||||
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Clobetasol propionate | 99.87% | Clobetasol propionate is a potent and selective CYP3A5 inhibitor with an IC50 of 0.206 μM. Clobetasol propionate has no inhibiting on CYP3A4 or other major CYPs. Clobetasol propionate is a corticosteroid and has the potential for psoriasis and other dermatoses research. | ||||||||||||||||||||
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