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CHIKV Related Products (45)
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Harringtonine
0 ImagesHarringtonine is a natural Cephalotaxus alkaloid that inhibits protein synthesis. Harringtonine has anti-chikungunya virus (CHIKV) activities with an EC50 of 0.24 μM. -
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- EIDD-1931
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Tat-beclin 1
0 ImagesTat-beclin 1, a peptide derived from a region of the autophagy protein (beclin 1), is a potent inducer of autophagy and interacts with negative regulator of autophagy, GAPR-1 (GLIPR2). Tat-beclin 1 decreases the accumulation of polyglutamine expansion protein aggregates and the replication of several pathogens (including HIV-1) in vitro, and reduces mortality in mice infected with chikungunya (CHIKV) or West Nile virus (WNV). -
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Umifenovir hydrochloride
0 ImagesUmifenovir hydrochloride is a potent, orally active broad-spectrum antiviral with activity against a number of enveloped and non-enveloped viruses. Umifenovir hydrochloride is used as an anti-influenza virus agent. Umifenovir hydrochloride could effectively inhibit the fusion of virus with host cells. Umifenovir hydrochloride is an efficient inhibitor of SARS-CoV-2 in vitro. Anti-inflammatory activity. -
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Umifenovir
0 ImagesUmifenovir is a potent, orally active broad-spectrum antiviral agent with activity against a number of enveloped and non-enveloped viruses. Umifenovir is used as an anti-influenza virus agent. Umifenovir could effectively inhibit the fusion of virus with host cells. Umifenovir is an efficient inhibitor of SARS-CoV-2 in vitro. Umifenovir shows anti-inflammatory activity. -
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EIDD 1931-13C,15N2
0 ImagesCat. No.: HY-W754608Synonyms: β-D-N4-Hydroxycytidine-13C,15N2; NHC-13C,15N2EIDD 1931-13C,15N2 (β-D-N4-Hydroxycytidine-13C,15N2) is the 13C- and 15N-labeled EIDD 19312 (HY-125033). EIDD-1931 (Beta-d-N4-hydroxycytidine; NHC) is a novel nucleoside analog and behaves as a potent?anti-virus agent. EIDD-1931 effectively inhibits the replication activity of?venezuelan equine encephalitis?virus (VEEV),?Chikungunya?virus (CHIKV) and?hepatitis?C virus (HCV) -
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Caulerpin
0 ImagesCat. No.: HY-N10650CAS No.: 26612-48-6Caulerpin is an orally active natural product with anti-tumor, anti-viral, anti-oxidant, anti-fungal, anti-bacteria and analgesic activities. Caulerpin acts as an inhibitor of mitochondrial ETC complex I and acetylcholinesterase. Caulerpin blocks hypoxia-induced activation of HIF-1α protein, inhibits VEGF secretion and tumor angiogenesis under hypoxic conditions, reduces the expression of NLRP3 and the production of pro-inflammatory cytokines, and suppresses the load of Mycobacterium tuberculosis. Caulerpin can be used in studies related to breast cancer, prostate cancer, tuberculosis and viral infections. -
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3-Ethoxy-5,6-dibromosalicylaldehyde
0 ImagesCat. No.: HY-123996CAS No.: 20041-64-93-ethoxy-5,6-dibromosalicylaldehyde is a potent, non-competitive, selective IRE1 (including IRE1α) inhibitor (IC50s: ∼0.12 μM for hIRE1α-cyto; 6 μM for yeast Ire1). 3-ethoxy-5,6-dibromosalicylaldehyde inhibits XBP-1 splicing. 3-ethoxy-5,6-dibromosalicylaldehyde induces Apoptosis. 3-ethoxy-5,6-dibromosalicylaldehyde upregulates the mRNA expression level of TXNIP, while downregulating the expression level of TXN. 3-ethoxy-5,6-dibromosalicylaldehyde exhibits anticancer activity against pancreatic cancer. 3-ethoxy-5,6-dibromosalicylaldehyde significantly inhibits chikungunya virus replication. -
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2-Thiouridine
0 Images2-Thiouridine is an orally active modified nucleobase. 2-Thiouridine stabilizes U:A base pairs and destabilizes U:G wobble base pairs. 2-Thiouridine significantly improves the efficiency and accuracy of nonenzymatic replication of mixed-sequence A/U-containing RNA templates. 2-Thiouridine exhibits antiviral activity against multiple positive-sense single-stranded RNA viruses (DENV2, ZIKV, YFV, JEV, WNV, CHIKV, human coronaviruses ( [HCoV]-229E, HCoV-OC43, SARS-CoV), and MERS-CoV). -
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NHC-triphosphate tetraammonium
0 ImagesCat. No.: HY-135867E -
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RA-0002034
0 ImagesSynonyms: RA-2034RA-0002034 is a Chikungunya virus (CHIKV) nsP2 protease inhibitor with an IC50 of 58 nM. RA-0002034 covalently modifies the catalytic cysteine in a site-specific manner. -
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- Ethyl palmitate
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4α-Phorbol 12,13-didecanoate
0 ImagesSynonyms: 4αPDD4α-Phorbol 12,13-didecanoate (4αPDD) is a transient receptor potential vanilloid 4 (TRPV4) agonist. 4α-Phorbol 12,13-didecanoate can promote Ca2+ influx, induce ATP release and function as an osmoreceptor. 4α-Phorbol 12,13-didecanoate can inhibit water intake and increase maximal micturition pressure in rats. 4α-Phorbol 12,13-didecanoate can be used for the researches of inflammation and infection, such as chikungunya virus (CHIKV). -
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Anti-Chikungunya virus E2 Antibody (CHK-265)
0 ImagesCat. No.: HY-P990825Anti-Chikungunya virus E2 Antibody (CHK-265) is mouse-derived IgG2c κ type antibody inhibitor, targeting to Chikungunya virus E2. Anti-Chikungunya virus E2 Antibody (CHK-265) reacts with a conserved epitope on the B domain of the E2 glycoprotein of chikungunya virus. Anti-Chikungunya virus E2 Antibody (CHK-265) can block viral entry and egress. Anti-Chikungunya virus E2 Antibody (CHK-265) can be used for the research of infection, such as Chikungunya virus (CHIKV), Mayaro (MAYV) and O’nyong’nyong virus (ONNV). -
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Amustaline dihydrochloride
0 ImagesCat. No.: HY-106991ACAS No.: 210584-54-6Synonyms: S-303 dihydrochlorideAmustaline (S-303) dihydrochloride, a nucleic acid-targeted alkylator, is an efficient pathogen inactivation agent for blood components containing red blood cells. Amustaline dihydrochloride has three components: an acridine anchor (an intercalator that targets nucleic acids non-covalently), an effector (a bis-alkylator group that reacts with nucleophiles), and a linker (a small flexible carbon chain containing a labile ester bond that hydrolyzes at neutral pH to yield non-reactive breakdown products). -
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NHC-triphosphate tetrasodium
0 ImagesCat. No.: HY-135867A -
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CHIKV-IN-2
0 ImagesCHIKV-IN-2 is a potent inhibitor against Chikungunya virus (CHIKV), with excellent cellular antiviral activity (EC90=270 nM) and improved liver microsomal stability. CHIKV-IN-2 shows inhibitory activity against a cellular target Dihydroorotate Dehydrogenase (DHODH), which interacts with various viruses and regulate their replication via depleting intracellular pyrimidine pools. -
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Anti-Mouse Ly6C Antibody (Monts 1)
0 ImagesCat. No.: HY-P990200Anti-Mouse Ly6C Antibody (Monts 1) is a rat-derived anti-mouse Ly6C IgG2a type antibody inhibitor. Anti-Mouse Ly6C Antibody (Monts 1) depletes monocytes, neutrophils, and some other granulocyte populations. Anti-Mouse Ly6C Antibody (Monts 1) can be used for the researches of cancer, immunology and infection, such as chikungunya (CHIKV) and aggressive tumor. -
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CHIKV-IN-6
0 ImagesCat. No.: HY-208145CAS No.: 1609009-17-7 -
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NHC-diphosphate triammonium
0 ImagesCat. No.: HY-135867FPurity: 98.80% -
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