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Results for "

Caesalpinia

" in MedChemExpress (MCE) Product Catalog:

20

Inhibitors & Agonists

1

Fluorescent Dye

19

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N2949
    Bonducellpin D

    		SARS-CoV Infection Cancer
    Bonducellpin D is a furanoditerpenoid lactone isolated from Caesalpinia minax. Bonducellpin D exhibits broad-spectrum inhibition potential against SARS-CoV M pro and MERS-CoV M pro, with an Ki of 467.11 and 284.86 nM, respectively. Bonducellpin D also exhibits moderate anti-cancer activity in vitro .
    Bonducellpin D
  • HY-N2981
    Caesalmin B

    		Antibiotic Infection
    Caesalmin B is a furanoditerpenoid lactone isolated from Caesalpinia minax. Caesalmin B exhibits antiviral activity .
    Caesalmin B
  • HY-133225
    Caesalpine A

    		Others Others
    Caesalpine A, a cassane-type diterpene, is a natural product that could be isolated from the seeds of Caesalpinia minax .
    Caesalpine A
  • HY-N2753
    7-Acetoxybonducellpin C

    		Parasite Infection
    7-Acetoxybonducellpin C, a diterpenoid, is a nature product that could be isolated from the seed kernels of Caesalpinia crista. 7-Acetoxybonducellpin C has antimalarial activity .
    7-Acetoxybonducellpin C
  • HY-N2735
    7,3',4'-Trihydroxy-3-benzyl-2H-chromene

    		Influenza Virus Infection Inflammation/Immunology
    7,3',4'-Trihydroxy-3-benzyl-2H-chromene is an reversible noncompetitive neuraminidase (NA) inhibitor. 7,3',4'-Trihydroxy-3-benzyl-2H-chromene can be isolated from the dried heartwood of Caesalpinia sappan L. 7,3',4'-Trihydroxy-3-benzyl-2H-chromene has potent NAs inhibitory activities with IC50 values of 34.6 µM [H1N1], 39.5 µM [H3N2], and 50.5µM [H9N2], respectively. 7,3',4'-Trihydroxy-3-benzyl-2H-chromene can be used for the research of influenza virus .
    7,3',4'-Trihydroxy-3-benzyl-2H-chromene
  • HY-N1745A
    3-Deoxysappanchalcone
    1 Publications Verification

    		 Influenza Virus Infection Inflammation/Immunology
    3-Deoxysappanchalcone is a naturally-occurring chalcone compound isolated from Caesalpinia sappan L.
    3-Deoxysappanchalcone
  • HY-N7583
    Norcaesalpinin E

    		Others Others
    Norcaesalpinin E is a natural cassane-type diterpene found in the seed kernels of Caesalpinia crista .
    Norcaesalpinin E
  • HY-N10424
    Brazilein

    		Apoptosis Inflammation/Immunology
    Brazilein is an important immunosuppressive component isolated from Caesalpinia sappan L. Brazilein induces apoptosis in mice spleen lymphocytes .
    Brazilein
  • HY-N1715
    2-Acetoxy-3-deacetoxycaesaldekarin e

    2-Acetoxy-3-deacetoxycaesaldekarin e (compound 11) is a furanoditerpene that can be found in Caesalpinia crista .
    2-Acetoxy-3-deacetoxycaesaldekarin e
  • HY-59001
    Sappanchalcone

    		Apoptosis Cancer
    Sappanchalcone, a flavonoid isolated from Caesalpinia sappan L., induces caspase-dependent and AIF-dependent apoptosis in human colon cancer cells .
    Sappanchalcone
  • HY-N9315
    Episappanol

    		TNF Receptor Interleukin Related Inflammation/Immunology
    Episappanol is a natural compound isolated from Caesalpinia sappan heartwood with anti-inflammatory activity. Episappanol significantly inhibits the IL-6 and TNF-α secretion .
    Episappanol
  • HY-44135
    7-Hydroxy-3-(4-hydroxybenzylidene)chroman-4-one

    		Others Others
    7-Hydroxy-3-(4-hydroxybenzylidene)chroman-4-one, a homoisoflavonoid, can be isolated from the dried heartwood of Caesalpinia sappan .
    7-Hydroxy-3-(4-hydroxybenzylidene)chroman-4-one
  • HY-N0800
    Protosappanin B

    (-)-Protosappanin B

    		 Apoptosis Cancer
    Protosappanin B is a phenolic compound extracted from Caesalpinia sappan. Anti-cancer activity . Protosappanin B induces apoptosis and causes G1 cell cycle arrest in human bladder cancer cells .
    Protosappanin B
  • HY-N0116
    Hematoxylin
    5 Publications Verification

    Natural Black 1; Haematoxylin

    		 Amyloid-β Others
    Hematoxylin (Natural Black 1), a naturally occurring flavonoid compound derived from Caesalpinia sappan Linn.. Hematoxylin is a nuclear stain in histology and is also a potent Aβ42 fibrillogenesis inhibitor with an IC50 of 1.6 μM.
    Hematoxylin
  • HY-N4299
    Caesappanin C

    		Others Metabolic Disease
    Caesappanin C, a biphenyl dimer from the ethanolic extract of the heartwood of Indonesian Caesalpinia sappan L., shows strong proliferation stimulating activity against the primary osteoblastic cells in vitro. Caesappanin C has the potential to stimulate bone formation and regeneration .
    Caesappanin C
  • HY-N10108
    Protosappanin A dimethyl acetal

    		Xanthine Oxidase Inflammation/Immunology
    Protosappanin A dimethyl acetal is a homoisoflavonoid. Protosappanin A dimethyl acetal can be isolated from Caesalpinia sappan. Protosappanin A dimethyl acetal is also a competive inhibitor with significant xanthine oxidase inhibitory activity (IC50=50.7 μM) .
    Protosappanin A dimethyl acetal
  • HY-113573
    Protosappanin A

    PTA

    		 JAK STAT Inflammation/Immunology
    Protosappanin A (PTA), an immunosuppressive ingredient and major biphenyl compound isolated from Caesalpinia sappan L, suppresses JAK2/STAT3-dependent inflammation pathway through down-regulating the phosphorylation of JAK2 and STAT3 .
    Protosappanin A
  • HY-N10069
    Bonducellin

    		Others Infection
    Bonducellin is a a homoisoflavonoid, which can be isolated from Caesalpinia digyna roots. Bonducellin is a potent inhibitor of efflux pump (EP), while EP induces resistance in mycobacteria and serves as a target of anti-TB (tuberculosis) agents. Bonducellin reduces MIC of EtBr by 8-fold against M. smegmatis (MIC=62.5 mg/L) .
    Bonducellin
  • HY-N1818
    Deoxysappanone B

    3-Deoxysappanone B

    		 p38 MAPK Neurological Disease Inflammation/Immunology
    Deoxysappanone B (3-Deoxysappanone B) is a homoisoflavone compound isolated from Caesalpinia sappan L (Lignum Sappan). Deoxysappanone B has anti-neuroinflammatory and neuroprotective effects and inhibits the production of neuroinflammatory mediators by blocking the IκB kinase (IKK)-NF-κB and p38/ERK MAPK pathways. Deoxysappanone B can be used in disease studies of neuritis and inflammation-related neurological damage .
    Deoxysappanone B
  • HY-N10843
    4-O-Methylepisappanol

    		Influenza Virus Infection
    4-O-Methylepisappanol (compound 9) is nature product that could be isolated from heartwood of Caesalpinia sappan. 4-O-Methylepisappanol is a potent neuraminidase inhibitor on the surface of influenza viruses with IC50 values of 42.8, 63.2, and 63.2 µM for A/Chicken/Korea/MS96/96 [H9N2], A/PR/8/34 [H1N1], and A/Hong Kong/8/68 [H3N2], respectively .
    4-O-Methylepisappanol

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