2. Search Result
Search Result
Results for "

DENV-2

" in MedChemExpress (MCE) Product Catalog:

19

Inhibitors & Agonists

2

Natural
Products

3

Recombinant Proteins

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W129596
    Policresulen

    		Virus Protease Infection
    Policresulen is a potent inhibitor of DENV2 NS2B/NS3 protease (IC50 of 0.48 μg/mL). Policresulen inhibits DENV2 replication in BHK-21 cells with IC50 of 4.99 μg/mL. Policresulen acts as a competitive inhibitor of the protease, and slightly affects the protease stability .
    Policresulen
  • HY-157550
    DENV-IN-12

    		Dengue virus Infection
    DENV-IN-12 (Compound 6) is a derivative of N-methylcytisine thio, which inhibits DENV-1 and DENV-2. DENV-IN-12 displays robust antiviral activity against DENV-2, with EC50 values ranging from 0.002 to 0.005 μM in different cell lines .
    <em>DENV</em>-IN-12
  • HY-155129
    Antiviral agent 36

    		DNA/RNA Synthesis Infection
    Antiviral agent 36 (compound 27) is a potent dengue (DENV) and Zika (ZIKV) viruses inhibitor. Antiviral agent 36 inhibits replication of Zika and dengue virus with EC50s of 100 nM, 90 nM, 210 nM, and 120 nM for ZIKV-FLR, ZIKV-HN16, DENV-2, and DENV-3, respectively .
    Antiviral agent 36
  • HY-N12691
    Antiviral agent 51

    		Dengue virus Infection
    Antiviral agent 51 (compound a) is a potent antiviral agent. Antiviral agent 51 is a fucoidan. Antiviral agent 51 interacts with DENV-2 RNA Dependant RNA polymerase (RdRp) .
    Antiviral agent 51
  • HY-152082
    DENV-IN-8

    		Flavivirus Dengue virus Virus Protease Infection
    DENV-IN-8 (Compound 5e) is a DENV2 inhibitor with an EC50 of 0.068 μM .
    <em>DENV</em>-IN-8
  • HY-152083
    DENV-IN-9

    		Flavivirus Dengue virus Virus Protease Infection
    DENV-IN-9 (Compound 5f) is a DENV2 inhibitor with an EC50 of 0.88 μM .
    <em>DENV</em>-IN-9
  • HY-144736
    NS2B/NS3-IN-4

    		Virus Protease Infection
    NS2B/NS3-IN-4 (Compound 34e) is an allosteric DENV2 and ZIKV NS2B/NS3 protease inhibitor with IC50 values of 0.69 µM and 1.04 µM against DENV2 and ZIKV NS2B/NS3 proteases, respectively .
    NS<em>2</em>B/NS3-IN-4
  • HY-144740
    NS2B/NS3-IN-5

    		Virus Protease Infection
    NS2B/NS3-IN-5 (Compound 25b) is an allosteric DENV2 and ZIKV NS2B/NS3 protease inhibitor with IC50 values of 0.67 µM and 4.38 µM against ZIKV and DENV2 NS2B/NS3 proteases, respectively .
    NS<em>2</em>B/NS3-IN-5
  • HY-108462
    ML-SA1
    2 Publications Verification

    		 Dengue virus TRP Channel Flavivirus Infection
    ML-SA1, as a selective TRPML agonist, inhibits Dengue virus 2 (DENV2) and Zika virus (ZIKV) by promoting lysosomal acidification and protease activity. The IC50 value of ML-SA1 against DENV2 RNA and ZIKV RNA is 8.3 μM and 52.99 μM, respectively. ML-SA1 induces autophagy. ML-SA1 can be used for the research of broad-spectrum antiviral .
    ML-SA1
  • HY-12957
    NITD008
    5 Publications Verification

    7-Deaza-2'-C-acetylene-adenosine
    NITD008 is a potent and selective flaviviruse inhibitor which can inhibit Dengue Virus Type 2 (DENV-2) with an EC50 of 0.64 μM. NITD008 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    NITD008
  • HY-115805
    YKL-04-085

    		Virus Protease Infection
    YKL-04-085 is potent inhibitors of viral translation, with an IC90 of 0.555 μM for DENV2. YKL-04-085 is devoid of any kinase activity .
    YKL-04-085
  • HY-N3942
    Glabranine

    		Flavivirus Dengue virus HIV Infection
    Glabranine, an flavonoid, is isolated from Tephrosia s.p, exerts a inhibitory effect in vitro on the dengue virus . Glabranine forms interaction with the soluble ectodomain of DENV type 2 (DENV2) E protein [2].
    Glabranine
  • HY-16696
    SN 2
    3 Publications Verification

    		 Flavivirus Dengue virus TRP Channel Infection
    SN 2 is a potent activator of TRPML3 ion channel with an EC50 of 1.8 μM . SN 2 also acts as a potent inhibitor of Dengue virus 2 (DENV2) and Zika virus (ZIKV) [2].
    SN <em>2</em>
  • HY-157405
    DENV-IN-11

    		Dengue virus Infection
    DENV-IN-11 (SC27), a sulfonamide chalcone, is a potent DENV inhibitor that targeted viral methyltransferase. DENV-IN-11 reduced DENV2 replicon replication. DENV-IN-11 can be used for dengue infection research .
    <em>DENV</em>-IN-11
  • HY-115929
    DENV-IN-4

    		DNA/RNA Synthesis Infection
    DENV-IN-4 is a potent DENV inhibitor (DENV EC50=4.79 μM, Vero CC50>100 μM, SI>20.9). DENV-IN-4 can inhibit the expression level of DENV2 with concentration-dependence and reduce RNA-dependent RNA polymerase (RdRp) enzymatic activity. DENV-IN-4 has antiviral effect .
    <em>DENV</em>-IN-4
  • HY-136575
    4-Hydroxy-2-methylbenzenesulfonic acid ammonium

    		Virus Protease Infection
    4-Hydroxy-2-methylbenzenesulfonic acid ammonium is an impurity of Policresulen. Policresulen is a potent NS2B/NS3 protease inhibitor with an IC50 of 0.48 μg/mL. Policresulen effectively inhibits the replication of DENV2 virus in BHK-21 cells with an IC50 of 4.99 μg/mL. Policresulen acted as a competitive inhibitor of the protease, and slightly affected the protease stability .
    4-Hydroxy-<em>2</em>-methylbenzenesulfonic acid ammonium
  • HY-136574
    2-Hydroxy-4-methylbenzenesulphonic acid ammonium

    		Virus Protease Infection
    2-Hydroxy-4-methylbenzenesulphonic acid ammonium is an impurity of Policresulen. Policresulen is a potent NS2B/NS3 protease inhibitor with an IC50 of 0.48 μg/mL. Policresulen effectively inhibits the replication of DENV2 virus in BHK-21 cells with an IC50 of 4.99 μg/mL. Policresulen acted as a competitive inhibitor of the protease, and slightly affected the protease stability .
    <em>2</em>-Hydroxy-4-methylbenzenesulphonic acid ammonium
  • HY-136573
    5-Hydroxytoluene-2,4-disulphonic acid diammonium

    		Virus Protease Infection
    5-Hydroxytoluene-2,4-disulphonic acid diammonium is an impurity of Policresulen. Policresulen is a potent NS2B/NS3 protease inhibitor with an IC50 of 0.48 μg/mL. Policresulen effectively inhibits the replication of DENV2 virus in BHK-21 cells with an IC50 of 4.99 μg/mL. Policresulen acted as a competitive inhibitor of the protease, and slightly affected the protease stability .
    5-Hydroxytoluene-<em>2</em>,4-disulphonic acid diammonium
  • HY-144645
    SP-471P

    		Flavivirus Dengue virus Virus Protease DNA/RNA Synthesis Infection
    SP-471P is a potent dengue virus (DENV) protease inhibitor with EC50s of 5.9 μM, 1.4 μM, 5.1 μM and 1.7 μM for DENV1, DENV2, DENV3 and DENV4, respectively and CC50 value over 100 μM. SP-471P can reduce DENV viral RNA synthesis .
    SP-471P

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: