Policresulen
Based on 1 Customer Validation
Policresulen is a competitive inhibitor for DENV2 NS2B/NS3 protease with an IC50 of 0.48 μg/mL. Policresulen can be used as a local hemostatic and antibacterial agent for research of cervical and vaginal inflammation, skin lesions, oral mucosa and gingival inflammation.
For research use only. We do not sell to patients.
- Purity: 51.60%
- CAS No.: 101418-00-2
- Formula: (C8H10O4S)n
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Policresulen inhibits the DENV2 replication in cell BHK-21 with an IC50 of 4.99 μg/mL. Policresulen exhibits mild cytotoxicity in cell BHK-21 with an IC50 of 459.45 μg/mL[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Guinea pig models[2]
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Dosage:360 mg/kg
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Administration:topical application to the cheek pouch mucosa, twice daily for 15 days
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Result:Decreased the level of E-cadherin, caused histological changes including epithelial hyperplasia, vesicular degeneration, and abnormal mitosis.
Chemical Information
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CAS No. 101418-00-2
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Appearance Liquid
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Formula (C8H10O4S)n
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Color Brown to orange
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SMILES
CC1=C(C)C(O)=C(S(=O)(O)=O)C=C1CC.[n]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
H2O : 100 mg/mL (Need ultrasonic)
DMSO : 50 mg/mL (Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Policresulen Related Classifications
HY-W129596 Related Classifications
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