DENV-IN-12
DENV-IN-12 (Compound 6) is a derivative of N-methylcytisine thio, which inhibits DENV-1 and DENV-2. DENV-IN-12 displays robust antiviral activity against DENV-2, with EC50 values ranging from 0.002 to 0.005 μM in different cell lines.
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- CAS No.: 2581065-80-5
- Formule: C12H14N2OS
- Masse moléculaire:234.32
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Description
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A549 | CC50 |
>50 μM
Compound: 6
|
Cytotoxicity against human A549 cells by MTT assay
Cytotoxicity against human A549 cells by MTT assay
|
[PMID: 38242331] |
| Vero C1008 | CC50 |
>50 μM
Compound: 6
|
Cytotoxicity against african green monkey Vero E6 cells by MTT assay
Cytotoxicity against african green monkey Vero E6 cells by MTT assay
|
[PMID: 38242331] |
Chemical Information
-
CAS No. 2581065-80-5
-
Masse moléculaire 234.32
-
Formule C12H14N2OS
-
SMILES
O=C1C=CC=C([C@@H]2C3)N1C[C@@H]3CN(C)C2=S
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Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)