NS2B/NS3-IN-4
NS2B/NS3-IN-4 (Compound 34e) is an allosteric DENV2 and ZIKV NS2B/NS3 protease inhibitor with IC50 values of 0.69 µM and 1.04 µM against DENV2 and ZIKV NS2B/NS3 proteases, respectively.
For research use only. We do not sell to patients.
- CAS No.: 2910757-30-9
- Formula: C15H11NO4
- Molecular Weight:269.25
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
IC50: 0.69 µM (DENV2 NS2B/NS3 protease), 1.04 µM (ZIKV NS2B/NS3 protease)[1]
Chemical Information
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CAS No. 2910757-30-9
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Molecular Weight 269.25
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Formula C15H11NO4
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SMILES
O=C(C1=CC2=CC(O)=C(C=C2O1)O)NC3=CC=CC=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)