1. Anti-infection
  2. Virus Protease
  3. NS2B/NS3-IN-5

NS2B/NS3-IN-5 (Compound 25b) is an allosteric DENV2 and ZIKV NS2B/NS3 protease inhibitor with IC50 values of 0.67 µM and 4.38 µM against ZIKV and DENV2 NS2B/NS3 proteases, respectively.

For research use only. We do not sell to patients.

NS2B/NS3-IN-5 Chemical Structure

NS2B/NS3-IN-5 Chemical Structure

CAS No. : 2910757-21-8

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Description

NS2B/NS3-IN-5 (Compound 25b) is an allosteric DENV2 and ZIKV NS2B/NS3 protease inhibitor with IC50 values of 0.67 µM and 4.38 µM against ZIKV and DENV2 NS2B/NS3 proteases, respectively[1].

IC50 & Target

IC50: 0.67 µM (ZIKV NS2B/NS3 protease), 4.38 µM (DENV2 NS2B/NS3 protease)[1]

Molecular Weight

412.20

Formula

C14H9IN2O3S

CAS No.
SMILES

O=C(C1=CC=C(C=C1)I)NC2=NC3=CC(O)=C(C=C3S2)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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NS2B/NS3-IN-5 Related Classifications

  • Molarity Calculator

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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NS2B/NS3-IN-5
Cat. No.:
HY-144740
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