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Results for "

HASPIN

" in MedChemExpress (MCE) Product Catalog:

20

Inhibitors & Agonists

3

Oligonucleotides

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-15424
    5-Iodotubercidin
    Maximum Cited Publications
    11 Publications Verification

    NSC 113939; 5-ITu

    		 Adenosine Kinase Cancer
    5-Iodotubercidin (NSC 113939), an ATP mimetic, is a potent adenosine kinase inhibitor with an IC50 of 26 nM. 5-Iodotubercidin (NSC 113939) initiates glycogen synthesis in isolated hepatocytes by causing inactivation of phosphorylase and activation of glycogen synthase. 5-Iodotubercidin (NSC 113939) also inhibits CK1, insulin receptor tyrosine kinase, phosphorylase kinase, PKA, CK2, PKC and Haspin .
    5-Iodotubercidin
  • HY-15217
    CHR-6494
    5+ Cited Publications

    		 Haspin Kinase Cancer
    CHR-6494 is a potent inhibitor of haspin, with an IC50 of 2 nM. CHR-6494 inhibits histone H3T3 phosphorylation. CHR-6494 can be used in the research of cancer .
    CHR-6494
  • HY-13455
    LDN-192960
    2 Publications Verification

    		 Haspin Kinase DYRK Cancer
    LDN-192960 is an inhibitor of Haspin and Dual-specificity Tyrosine-regulated Kinase 2 (DYRK2) with IC50s of 10 nM and 48 nM, respectively .
    LDN-192960
  • HY-110320
    LDN-209929 dihydrochloride

    		Haspin Kinase DYRK Cancer
    LDN-209929 dihydrochloride is a potent and selective haspin kinase inhibitor (IC50=55 nM) with180-fold selectivity verses DYRK2 (IC50=9.9 μM). LDN-209929 is a optimized analogue of LDN-192960 (HY-13455) .
    LDN-209929 dihydrochloride
  • HY-146636
    Haspin-IN-3

    		Haspin Kinase Cancer
    Haspin-IN-3 (compound 8l) is a potent haspin inhibitor with IC50 of 14 nM. Haspin-IN-3 has anticancer effects .
    Haspin-IN-3
  • HY-13455A
    LDN-192960 hydrochloride
    2 Publications Verification

    		 Haspin Kinase DYRK Cancer
    LDN-192960 hydrochloride is an inhibitor of Haspin and Dual-specificity Tyrosine-regulated Kinase 2 (DYRK2) with IC50s of 10 nM and 48 nM, respectively .
    LDN-192960 hydrochloride
  • HY-100368
    MELK-8a
    3 Publications Verification

    NVS-MELK8a

    		 PDGFR Haspin Kinase MELK Mitosis Cancer
    MELK-8a (NVS-MELK8a) is a highly potent and selective maternal embryonic leucine zipper kinase (MELK) inhibitor with IC50 of 2 nM. MELK-8a also inhibits Flt3 (ITD), Haspin, PDGFRα with IC50s of 0.18, 0.19, and 0.42 μM, respectively. MELK plays an essential role in regulating cell mitosis in a subset of cancer cells .
    MELK-8a
  • HY-163858
    Haspin-IN-4

    		Haspin Kinase Cancer
    Haspin-IN-4 (Compound 60) is a selective inhibitor of Haspin with an IC50 value of 0.01 nM. Haspin-IN-4 possesses anticancer activity and can be used in cancer research .
    Haspin-IN-4
  • HY-146586
    Haspin-IN-1

    		Haspin Kinase CDK DYRK Cancer
    Haspin-IN-1 (compound 2a) is a haspin inhibitor with an IC50 of 119 nM. Haspin-IN-1 also inbibits CLK1 and DYRK1A with IC50s of 221 nM and 916.3 nM, respectively .
    Haspin-IN-1
  • HY-15424R
    5-Iodotubercidin (Standard)

    NSC 113939 (Standard); 5-ITu (Standard)

    		 Adenosine Kinase Reference Standards Cancer
    5-Iodotubercidin (Standard) is the analytical standard of 5-Iodotubercidin. This product is intended for research and analytical applications. 5-Iodotubercidin (NSC 113939), an ATP mimetic, is a potent adenosine kinase inhibitor with an IC50 of 26 nM. 5-Iodotubercidin (NSC 113939) initiates glycogen synthesis in isolated hepatocytes by causing inactivation of phosphorylase and activation of glycogen synthase. 5-Iodotubercidin (NSC 113939) also inhibits CK1, insulin receptor tyrosine kinase, phosphorylase kinase, PKA, CK2, PKC and Haspin .
    5-Iodotubercidin (Standard)
  • HY-155341
    HSK205

    		FLT3 Haspin Kinase Cancer
    HSK205 is a dual FLT3 and haspin inhibitor, with IC50 of 0.187 nM for FLT3. HSK205 has antitumor activity .
    HSK205
  • HY-170546
    MU1920

    		Haspin Kinase Cancer
    MU1920 is an ATP-competitive, selective inhibitor for haspin with an IC50 of 6 nM. MU1920 exhibits good pharmacokinetic properties and metabolic stability in mouse plasma and microsomes without obvious anticancer effects, which can be used for development of chemical probes .
    MU1920
  • HY-110350
    CHR-6494 TFA

    		Haspin Kinase Cancer
    CHR-6494 TFA is a potent inhibitor of haspin, with an IC50 of 2 nM. CHR-6494 TFA inhibits histone H3T3 phosphorylation. CHR-6494 TFA induces the apoptosis of cancer cells, including melanoma and breast cancer. CHR-6494 TFA can be used in the research of cancer .
    CHR-6494 TFA
  • HY-146587
    Haspin-IN-2

    		Haspin Kinase CDK DYRK Cancer
    Haspin-IN-2 (compound 4) is a potent and selective haspin inhibitor with an IC50 of 50 nM. Haspin-IN-1 also inbibits CLK1 and DYRK1A with IC50s of 445 nM and 917 nM, respectively .
    Haspin-IN-2
  • HY-135002
    LDN-209929

    		Haspin Kinase Cancer
    LDN-209929 is a potent haspin kinase inhibitor, with IC50 values of 55 nM and 9.9 μM for Haspin and DYRK2, respectively .
    LDN-209929
  • HY-RS06011
    Haspin Rat Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Haspin Rat Pre-designed siRNA Set A contains three designed siRNAs for Haspin gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Haspin Rat Pre-designed siRNA Set A
    Haspin Rat Pre-designed siRNA Set A
  • HY-RS06010
    Haspin Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Haspin Mouse Pre-designed siRNA Set A contains three designed siRNAs for Haspin gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Haspin Mouse Pre-designed siRNA Set A
    Haspin Mouse Pre-designed siRNA Set A
  • HY-RS06009
    HASPIN Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    HASPIN Human Pre-designed siRNA Set A contains three designed siRNAs for HASPIN gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    HASPIN Human Pre-designed siRNA Set A
    HASPIN Human Pre-designed siRNA Set A
  • HY-112366
    FLT3-IN-38

    		FLT3 Haspin Kinase Cancer
    FLT3-IN-38 (Flt-3 Inhibitor II) is a FLT3 inhibitor. FLT3-IN-38 has off-target effects and inhibits serine/threonine kinase haspin. Haspin is a mitotic signal coordinator. FLT3-IN-38 can be used for cancer research .
    FLT3-IN-38
  • HY-179486
    Anticancer agent 285

    		Haspin Kinase Cancer
    Anticancer agent 285 is an orally active anticancer agent with highly effective and selective haspin-inhibiting IC50 = 18 nM) activity. Anticancer agent 285 can be used for the study of colorectal cancer[1].
    Anticancer agent 285

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