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Cat. No.: HY-112366

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FLT3-IN-38

FLT3-IN-38 (Flt-3 Inhibitor II) is a FLT3 inhibitor. FLT3-IN-38 has off-target effects and inhibits serine/threonine kinase haspin. Haspin is a mitotic signal coordinator. FLT3-IN-38 can be used for cancer research.

For research use only. We do not sell to patients.

CAS No.: 896138-40-2
Formula: C₁₇H₁₂N₂O₃
Molecular Weight:292.29

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

FLT3-IN-38 Chemical Structure

CAS No.: 896138-40-2

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Sample (0.1mg)

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(In Japan)

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Bioz

Biological Activity

Description

Cellular Effect

Cell Line	Type	Value	Description	References
EOL1	IC₅₀	0.04 μM Compound: 102	Inhibition of endogenous FLT3 in EOL1 cells Inhibition of endogenous FLT3 in EOL1 cells	[PMID: 16722630]
K562	IC₅₀	4.2 μM Compound: 102	Inhibition of oncogenic Bcr-Abl kinase in K562 cells Inhibition of oncogenic Bcr-Abl kinase in K562 cells	[PMID: 16722630]

Chemical Information

CAS No. 896138-40-2
Molecular Weight 292.29
Formula C₁₇H₁₂N₂O₃
SMILES

O=C(C(N1)=CC2=C1C=CC(O)=C2)C(N3)=CC4=C3C=CC(O)=C4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Gao Y, et al. A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery. Biochem J. 2013 Apr 15;451(2):313-28. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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