31 Results for "

Neuromedin L

" in MedChemExpress (MCE) Product Catalog:
Products (31)

31 Results for "Neuromedin L" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-P0187
CAS No.: 106128-89-6
Target:  

Neurokinin Receptor

Research Areas:  

Neurological Disease Endocrinology

Senktide is a potent, selective agonist of the neuromedin K3 (NK3) receptor (EC50=0.5-3 nM). Senktide less potently agonizes the NK1 receptor (EC50=35 µM). Senktide is promising for research of neurological disease .
loading...
    loading...
3
3 Cited Publications
Cat. No.: HY-P0197
CAS No.: 86933-74-6
Synonyms: Substance K; Neurokinin α; Neuromedin L; NKA
Target:  

Neurokinin Receptor

Research Areas:  

Neurological Disease Endocrinology

Neurokinin A (Substance K), a peptide neurotransmitter of the tachykinin family, acts via the NK-2 receptor. Neurokinin A acts as a major mediator in human airway and gastrointestinal tissues .
loading...
    loading...
3
3 Cited Publications
Cat. No.: HY-P0197A
CAS No.: 2828433-19-6
Synonyms: Substance K TFA; Neurokinin α TFA; Neuromedin L TFA; NKA TFA
Target:  

Neurokinin Receptor

Research Areas:  

Neurological Disease Endocrinology

Neurokinin A TFA (Substance K TFA), a peptide neurotransmitter of the tachykinin family, acts via the NK-2 receptor. Neurokinin A acts as a major mediator in human airway and gastrointestinal tissues .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-103286
CAS No.: 204067-01-6
Purity:  99.38%
Target:  

Bombesin Receptor

Research Areas:  

Cancer

PD176252 is a potent antagonist of neuromedin-B preferring (BB1) and gastrin-releasing peptide-preferring (BB2) receptor with Kis of 0.17 nM and 1 nM for human BB1 and BB2 receptors, and 0.66 nM, 16 nM for Rat BB1 and BB2 receptors, respectively; PD176252 is also an agonist of N-Formyl peptide receptor1/2 (FPR1/FPR2), with EC50s of 0.31 and 0.66 μM in HL-60 cells.
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-P0079
CAS No.: 92169-45-4
Synonyms: Neuromedin N (rat, mouse, porcine, canine)
Target:  

Dopamine Receptor

Research Areas:  

Neurological Disease

Neuromedin N is a potent modulator of dopamine D2 receptor agonist binding in rat neostriatal membranes.
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P0241
CAS No.: 87096-84-2
Neuromedin B (NMB) is a member of Bombesin (BN)-like peptide family in mammals.
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-103277A
Purity:  96.20%
Target:  

Bombesin Receptor

BIM 23042 TFA, a certain somatostatin (SS) octapeptide analogue, is a selective neuropeptide neuromedin B receptor (NMB-R, BB1) antagonist. BIM 23042 has 100-fold lower affinity for gastrin-releasing peptide (GRP) receptor (BB2). BIM 23042 inhibits Neuromedin?B?(HY-P0241), ICI 216140 and DPDM-bombesin ethylamide-induced Ca 2+ release .
loading...
    loading...
Cat. No.: HY-116216
CAS No.: 204066-82-0
Purity:  98.78%
Target:  

Bombesin Receptor

Research Areas:  

Cancer

PD 168368 is a potent, competitive, and selective neuromedin B receptor (NMB-R) antagonist with the Ki of 15–45 nM . PD 168368 is neuromedin B receptor (NMBR; IC50=96 nM) / gastrin-releasing peptide receptor (GRPR IC50=3500 nM) antagonist . PD 168368 also is a mixed FPR1/FPR2/FPR3 agonist with EC50s of 0.57, 0.24, and 2.7 nM, respectively .
loading...
    loading...
Cat. No.: HY-P1423A
Target:  

Bombesin Receptor

Research Areas:  

Metabolic Disease Cancer

BA 1 TFA is a potent agonist for the bombesin (BB) family of receptors. BA1 binds with high affinity to Bombesin receptor subtype-3 (BRS3), gastrin releasing peptide receptor (GRPR), neuromedin B receptor (NMBR) with IC50s of 6, 0.4, 2.5 nM .
loading...
    loading...
Cat. No.: HY-P1238A
Synonyms: Neuromedin U (rat) TFA; Rat Neuromedin U-23 TFA
Research Areas:  

Neurological Disease

Neuromedin U, rat TFA is a 23-amino acid brain-gut peptide. Neuromedin U (NMU), through its cognate receptor NMUR2 in the central nervous system, regulates several important physiological functions, including energy balance, stress response, and nociception.
loading...
    loading...
Cat. No.: HY-P2378
CAS No.: 312306-89-1
Target:  

Endogenous Metabolite

Research Areas:  

Cardiovascular Disease

Neuromedin U-25 human is the active form of neuromedin U in human. Neuromedin U-25 human inhibits glucose-stimulated insulin secretion, which leads to early-onset obesity. Neuromedin U-25 serves as vasoconstrictor in human vascular beds .
loading...
    loading...
Cat. No.: HY-N6629
CAS No.: 76666-32-5
3'-Methoxyflavonol is a selective agonist of neuromedin U 2 receptor (NMU2R).
loading...
    loading...
Cat. No.: HY-103277
CAS No.: 111857-96-6
Target:  

Bombesin Receptor

BIM 23042, a certain somatostatin (SS) octapeptide analogue, is a selective neuropeptide neuromedin B receptor (NMB-R, BB1) antagonist. BIM 23042 has 100-fold lower affinity for gastrin-releasing peptide (GRP) receptor (BB2). BIM 23042 inhibits Neuromedin?B?(HY-P0241), ICI 216140 and DPDM-bombesin ethylamide-induced Ca 2+ release .
loading...
    loading...
Cat. No.: HY-P3134A
Research Areas:  

Metabolic Disease

CPN-267 (compound 7b) TFA is a selective neuromedin U receptor 1 (NMUR1) agonist with the EC50 of 0.25 nM. CPN-267 TFA suppresses body weight gain in mice and can be used for study of obesity .
loading...
    loading...
Cat. No.: HY-103283
CAS No.: 81608-30-2
Purity:  98.29%
Synonyms: GRP(18-27) (porcine)
Research Areas:  

Neurological Disease

Neuromedin C porcine (GRP, 18-27, porcine) is a bombesin-like neuropeptide that can be obtained from porcine spinal cord. Neuromedin C porcine exhibits a potent contractile activity on rat uterus in the characteristic manner of bombesin. Neuromedin C porcine has research potential for neurological-related diseases .
loading...
    loading...
Cat. No.: HY-P1238
CAS No.: 117505-80-3
Synonyms: Neuromedin U (rat); Rat Neuromedin U-23
Research Areas:  

Neurological Disease

Neuromedin U, rat is a 23-amino acid brain-gut peptide. Neuromedin U (NMU), through its cognate receptor NMUR2 in the central nervous system, regulates several important physiological functions, including energy balance, stress response, and nociception.
loading...
    loading...
Cat. No.: HY-124681
CAS No.: 1003000-59-6
Research Areas:  

Metabolic Disease

NY0116 is a neuromedin U receptor 2 (NMUR2) agonist with EC50 values of 27.76 μM for hNMUR1 and 13.61 μM for hNMUR2. NY0116 decreases cAMP while stimulating calcium signaling in stably expressing NMUR2 HEK293 cells .
loading...
    loading...
Cat. No.: HY-P1423
CAS No.: 183241-31-8
Target:  

Bombesin Receptor

Research Areas:  

Metabolic Disease Cancer

BA 1 is a potent agonist for the bombesin (BB) family of receptors. BA 1 binds with high affinity to Bombesin receptor subtype-3 (BRS3), gastrin releasing peptide receptor (GRPR), neuromedin B receptor (NMBR) with IC50s of 6, 0.4, 2.5 nM .
loading...
    loading...
Cat. No.: HY-P1239
CAS No.: 843782-19-4
Target:  

Inhibitory Antibodies

Research Areas:  

Neurological Disease

Neuromedin S(rat) is a 34-amino acids peptide from rat Neuromedin S. Neuromedin S is a neuropeptide isolated from rat brain. Neuromedin S acts as a ligand for the G protein-coupled receptor FM4/TGR-1
loading...
    loading...
Cat. No.: HY-P1239A
Target:  

Inhibitory Antibodies

Research Areas:  

Neurological Disease

Neuromedin S(rat) TFA is a 34-amino acids peptide from rat Neuromedin S. Neuromedin S is a neuropeptide isolated from rat brain. Neuromedin S acts as a ligand for the G protein-coupled receptor FM4/TGR-1
loading...
    loading...