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Cat. No.: HY-P3134

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CPN-267

CPN-267 (compound 7b) is a selective neuromedin U receptor 1 (NMUR1) agonist with the EC₅₀ of 0.25 nM. CPN-267 suppresses body weight gain in mice and can be used for study of obesity.

For research use only. We do not sell to patients.

CAS No.: 2241236-26-8
Formula: C₅₀H₆₆N₁₆O₈S
Molecular Weight:1051.23

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

CPN-267 Chemical Structure

CAS No.: 2241236-26-8

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

CPN-267 (compound 7b) is a selective neuromedin U receptor 1 (NMUR1) agonist with the EC₅₀ of 0.25 nM. CPN-267 suppresses body weight gain in mice and can be used for study of obesity^[1].

All Neuromedin U Receptor (NMUR) Isoforms :

NMUR1
NMUR2

Chemical Information

CAS No. 2241236-26-8
Molecular Weight 1051.23
Formula C₅₀H₆₆N₁₆O₈S
Sequence

{2-Thienylacetyl}-{Trp(α-Me}-Trp-Arg-Pro-Arg-Asn-NH2
Sequence Shortening

{2-Thienylacetyl}-{Trp(α-Me}-WRPRN-NH2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (258 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Takayama K, et al. Discovery of a Human Neuromedin U Receptor 1-Selective Hexapeptide Agonist with Enhanced Serum Stability [published correction appears in J Med Chem. 2017 Sep 14;60(17):7613. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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