1. GPCR/G Protein Neuronal Signaling
  2. Dopamine Receptor
  3. Neuromedin N

Neuromedin N  (Synonyms: Neuromedin N (rat, mouse, porcine, canine))

Cat. No.: HY-P0079 Purity: 99.61%
COA Handling Instructions

Neuromedin N is a potent modulator of dopamine D2 receptor agonist binding in rat neostriatal membranes.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Neuromedin N Chemical Structure

Neuromedin N Chemical Structure

CAS No. : 92169-45-4

Size Price Stock Quantity
Solid + Solvent
10 mM * 1 mL in Water
ready for reconstitution
USD 177 In-stock
10 mM * 1 mL in Water USD 177 In-stock
5 mg USD 108 In-stock
10 mg USD 156 In-stock
25 mg USD 336 In-stock
50 mg   Get quote  
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Customer Review

Based on 3 publication(s) in Google Scholar

Top Publications Citing Use of Products

    Neuromedin N purchased from MedChemExpress. Usage Cited in: Cell Signal. 2018 Dec;52:147-154.  [Abstract]

    Human PASMCs are treated with Neuromedin N (400 nM) for various durations, cell lysates are prepared and phosphorylated forms of ERK (pERK), Stat3 (pStat3), Raf-1 (pRaf-1) and MEK (pMEK) are monitored by Western blotting using pERK1/2 (T202/Y204), pStat3 (Y705), pRaf-1 (S338) and pMEK1/2 (S217/221) antibodies.
    • Biological Activity

    • Purity & Documentation

    • References

    • Customer Review


    Neuromedin N is a potent modulator of dopamine D2 receptor agonist binding in rat neostriatal membranes.

    IC50 & Target

    Dopamine D2 receptor[1].

    In Vitro

    Neuromedin N competitively inhibits the binding of neurotensin to rat brain synaptic membranes with a 19-fold lower potency than neurotensin and is rapidly inactivated by brain synaptic peptidases[1]. It competitively inhibits neurotensin binding to rat brain synaptic membranes and has increased potency in the presence of the peptidase inhibitor bestatin[2].

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

    Molecular Weight






    CAS No.


    Sequence Shortening



    Room temperature in continental US; may vary elsewhere.


    Sealed storage, away from moisture

    Powder -80°C 2 years
    -20°C 1 year

    *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

    Solvent & Solubility
    In Vitro: 

    H2O : 50 mg/mL (67.03 mM; Need ultrasonic)

    Stock Solutions
    Concentration Solvent Mass 1 mg 5 mg 10 mg
    1 mM 1.3406 mL 6.7029 mL 13.4057 mL
    5 mM 0.2681 mL 1.3406 mL 2.6811 mL
    10 mM 0.1341 mL 0.6703 mL 1.3406 mL
    *Please refer to the solubility information to select the appropriate solvent.
    In Vivo:
    • 1.

      Add each solvent one by one:  PBS

      Solubility: 50 mg/mL (67.03 mM); Clear solution; Need ultrasonic

    *All of the co-solvents are available by MedChemExpress (MCE).
    Purity & Documentation
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    Neuromedin N Related Classifications

    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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    This equation is commonly abbreviated as: C1V1 = C2V2

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    × = ×
    C1   V1   C2   V2

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