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Surfactant proteins

" in MedChemExpress (MCE) Product Catalog:

37

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18

Biochemical Assay Reagents

3

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2

Isotope-Labeled Compounds

2

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Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-15435
    CHAPS
    4 Publications Verification

    		 Exosomes Biochemical Assay Reagents Others
    CHAPS is a cholic acid-derived, sulfobetaine-type zwitterionic detergent and micelle-forming agent. CHAPS exhibits properties of weak cationic or nonionic surfactants in different solution systems, undergoes micellization, and forms small, loose hydrophilic aggregates that are temperature-dependent. CHAPS stabilizes mononucleosomes under different ionic strengths, reduces nucleosome sequence specificity, promotes sliding of histone cores along DNA, solubilizes Tamm-Horsfall protein to reduce its interference with urinary exosome isolation, and maintains vesicle structure and the activity of related proteins at the same time. CHAPS is used to recover native folded fusion proteins, enhance the binding capacity of GST fusion proteins, and restore GST enzyme activity. However, CHAPS cannot refold proteins denatured by urea, guanidine hydrochloride or heat, nor can it construct the structure of intrinsically disordered proteins. CHAPS is commonly used in research on the separation and purification of membrane proteins .
    CHAPS
  • HY-Y0316
    Sodium dodecyl sulfate
    5 Publications Verification

    Sodium lauryl sulfate; Laurylsulfuric acid sodium salt

    		 Environmental Pollutants Biochemical Assay Reagents Others
    Sodium dodecyl sulfate is an anionic surfactant commonly used as a detergent, emulsifier, and protein denaturant in various industrial processes, especially in the production of personal care products, cleaners, and laboratory reagents. Sodium dodecyl sulfate has unique chemical properties that make it an effective ingredient in many applications, helping to reduce surface tension and enhance cleaning power.
    Sodium dodecyl sulfate
  • HY-B1268
    Docusate Sodium
    2 Publications Verification

    Dioctyl sulfosuccinate sodium salt

    		 Environmental Pollutants HSV Others
    Docusate Sodium (Dioctyl sulfosuccinate sodium salt) is one of the main components in stool softeners. Docusate Sodium is a sulfated surfactant and may inactivate viral pathogens by disrupting viral envelopes and/or denaturing/disassociating proteins. Docusate Sodium is effective in vitro against wild type and drug-resistant strains of HSV type 1 and 2. Docusate Sodium is an obesogen. Docusate Sodium with developmental exposure leads to increased adult adiposity, inflammation, metabolic disorder and dyslipidemia in offspring fed a standard diet in mice .
    Docusate Sodium
  • HY-108294
    Nonaethylene glycol monododecyl ether

    Nonaoxyethylene monododecyl ether

    		 Biochemical Assay Reagents Others
    Nonaethylene glycol monododecyl ether (Nonaoxyethylene monododecyl ether) is a nonionic surfactant and polyethylene glycol (PEG) detergent that can be used to form initial coalesced O/W emulsion droplets, as well as for protein separation and purification .
    Nonaethylene glycol monododecyl ether
  • HY-15435A
    CHAPS hydrate
    4 Publications Verification

    		 Biochemical Assay Reagents Exosomes Others
    CHAPS hydrate is a cholic acid-derived, sulfobetaine-type zwitterionic detergent and micelle-forming agent. CHAPS hydrate exhibits properties of weak cationic or nonionic surfactants in different solution systems, undergoes micellization, and forms small, loose hydrophilic aggregates that are temperature-dependent. CHAPS hydrate stabilizes mononucleosomes under different ionic strengths, reduces nucleosome sequence specificity, promotes sliding of histone cores along DNA, solubilizes Tamm‑Horsfall protein to reduce its interference with urinary exosome isolation, and maintains vesicle structure and the activity of related proteins at the same time. CHAPS hydrate is used to recover native folded fusion proteins, enhance the binding capacity of GST fusion proteins, and restore GST enzyme activity. However, CHAPS hydrate cannot refold proteins denatured by urea, guanidine hydrochloride or heat, nor can it construct the structure of intrinsically disordered proteins. CHAPS hydrate is commonly used in research on the separation and purification of membrane proteins .
    CHAPS hydrate
  • HY-126377
    Sulfobetaine 10

    		Biochemical Assay Reagents Others
    Sulfobetaine 10, is a zwitterionic surfactant commonly used in biochemistry and biophysics. It is commonly used to dissolve membrane proteins and other hydrophobic molecules in aqueous solutions. Sulfobetaine 10 has both positively and negatively charged groups in its structure, which allows it to maintain a neutral charge in solution and reduces its tendency to denature proteins. It is considered a mild, non-denaturing surfactant and is widely used in protein research.
    Sulfobetaine 10
  • HY-W250195
    Hexaethylene glycol monotetradecyl ether

    		Biochemical Assay Reagents Others
    Hexaethylene glycol monotetradecyl ether is a kind of nonionic surfactant with hydrophilic head and lipophilic tail. It belongs to the class of polyethylene glycol (PEG) ethers and is widely used in different industrial and research applications. Due to its unique properties, Hexaethylene glycol monotetradecyl ether is commonly used in lotions, detergents and solubilizers. It is particularly useful in the study of membrane proteins and can be used to stabilize and solubilize proteins for use in structural analysis techniques. Due to its moisturizing and emulsifying properties, Hexaethylene glycol monotetradecyl ether is also used in personal care and cosmetics.
    Hexaethylene glycol monotetradecyl ether
  • HY-P4371
    Hel 13-5

    		Biochemical Assay Reagents Inflammation/Immunology
    Hel 13-5 is a monomeric, lipophilic, basic amphipathic α-helical synthetic peptide composed of 18 amino acid residues. Hel 13-5 is designed as a substitute for proteins in artificial pulmonary surfactants, and it mimics the interaction between the N-terminal fragment of human pulmonary surfactant protein B and lipids. Hel 13-5 can bind to phospholipids for the development of pulmonary surfactant model systems. Hel 13-5 can be used in studies related to respiratory distress syndrome .
    Hel 13-5
  • HY-44157
    ALS-I

    		Biochemical Assay Reagents Neurological Disease
    ALS-I, an acid-Liable surfactant, is adopted for in-solution enzymatic digestions, can help to solubilize hydrophobic proteins. ALS-I is significantly enhanced peptide recovery for mass spectrometry (MS) mapping in the study of the proteomes of regenerating rat retina and mouse brain .
    ALS-I
  • HY-P2207
    Sinapultide

    		Biochemical Assay Reagents Others
    Sinapultide is a 21-amino-acid peptide that mimics the action of human surfactant protein-B (SP-B). Sinapultide can be used for synthetic phospholipids surfactants improvement .
    Sinapultide
  • HY-123622
    CYMAL-5, 98% (TLC)

    		Biochemical Assay Reagents Others
    CYMAL-5, 98% (TLC) is a cycloalkyl aliphatic saccharide. CYMAL-5, 98% (TLC) is a glycosidic surfactant (GS) with a chiral maltose polar head group and a cyclohexyl-pentyl hydrophobic tail. CYMAL-5, 98% (TLC) is a non-ionic detergent that has a tenfold lower critical micelle concentration (CMC) in comparison with OG, and has previously been used for membrane protein extraction or crystallization of membrane proteins for X-ray crystallographic studies .
    CYMAL-5, 98% (TLC)
  • HY-W284558
    Sodium hexadecyl sulfate

    		Biochemical Assay Reagents Others
    Sodium hexadecyl sulfate is a long-chain anionic surfactant. Sodium hexadecyl sulfate can act as an interface-regulating substance to form a soft layer on the surface of carbon nanotubes, guide proteins to adsorb in the correct orientation with active sites facing outward through electrostatic interactions, and significantly enhance the activity of immobilized enzymes. Sodium hexadecyl sulfate can replace or supplement SDS (HY-Y0316) in capillary gel electrophoresis (CGE) .
    Sodium hexadecyl sulfate
  • HY-W099575
    Sulfobetaine-16

    		Biochemical Assay Reagents Others
    3-(Hexadecyldimethylammonio)propane-1-sulfonate is an organic compound belonging to the class of sulfonates. It is a quaternary ammonium surfactant commonly used in various industrial and laboratory applications such as the production of detergents, personal care products and pharmaceuticals. 3-(Hexadecyldimethylammonio)propane-1-sulfonate is surface active and can be used as an emulsifier, foaming agent and wetting agent. In addition, it is used as a solubilizer in protein purification and as a surfactant in chromatography.
    Sulfobetaine-16
  • HY-B1268R
    Docusate Sodium (Standard)

    Dioctyl sulfosuccinate sodium salt (Standard)

    		 Reference Standards HSV Others
    Docusate (Sodium) (Standard) is the analytical standard of Docusate (Sodium). This product is intended for research and analytical applications. Docusate Sodium (Dioctyl sulfosuccinate sodium salt) is one of the main components in stool softeners. Docusate Sodium is a sulfated surfactant and may inactivate viral pathogens by disrupting viral envelopes and/or denaturing/disassociating proteins. Docusate Sodium is effective in vitro against wild type and drug-resistant strains of HSV type 1 and 2. Docusate Sodium is an obesogen. Docusate Sodium with developmental exposure leads to increased adult adiposity, inflammation, metabolic disorder and dyslipidemia in offspring fed a standard diet in mice .
    Docusate Sodium (Standard)
  • HY-D1005I
    Poloxamer L61

    		Biochemical Assay Reagents Others
    Poloxamer L61 is a non-ionic triblock copolymer surfactant. Poloxamer L61 effectively achieves intracellular molecular delivery to cancer cells during photoacoustic molecular delivery, and maintains cell viability by promoting cell membrane resealing, thus avoiding irreversible damage caused by laser-induced membrane permeabilization. Poloxamer L61 is a key component of SP1017, a compound related to gene therapy, which regulates the interaction between DNA and extracellular matrix as well as cellular uptake, and significantly enhances the distribution and bioavailability of plasmid DNA in skeletal muscle. Poloxamer L61 can be used in studies on local or systemic therapeutic protein production .
    Poloxamer L61
  • HY-W250172
    Polyethylene glycol tert-octylphenyl ether X-405 (70% in H2O)

    		Biochemical Assay Reagents Others
    Polyethylene glycol tert-octylphenyl ether X-405 (70% in H2O) is a nonionic surfactant commonly used in a variety of industrial and research applications. Polyethylene glycol tert-octylphenyl ether X-405 (70% in H2O) belongs to the family of polyethylene glycol (PEG) ethers with a hydrophilic head and lipophilic tail and is suitable for use in emulsions, detergents and solubilizers. Polyethylene glycol tert-octylphenyl ether X-405 (70% in H2O) is particularly useful in the study of membrane proteins, where it is used to solubilize and stabilize proteins for structural analysis techniques. It is also used in a variety of other applications, including drug delivery systems, nanotechnology, and diagnostic analysis. Additionally, Polyethylene glycol tert-octylphenyl ether X-405 (70% in H2O) is used in the production of microemulsions, salves and lotions due to its emulsifying and solubilizing properties. However, it can be toxic if ingested or inhaled, so proper handling and safety precautions are required.
    Polyethylene glycol tert-octylphenyl ether X-405 (70% in H2O)
  • HY-W250176
    Polyethylene glycol trimethylnonyl ether

    		Biochemical Assay Reagents Others
    Polyethylene glycol trimethylnonyl ether, is a nonionic surfactant commonly used in various industrial and research applications. It belongs to the family of polyethylene glycol (PEG) ethers with a hydrophilic head and lipophilic tail and is suitable for use in lotions, detergents and solubilizers. Polyethylene glycol trimethylnonyl ether is particularly useful in protein chemistry, where it is used to solubilize and stabilize proteins, such as membrane proteins, for structural analysis techniques. In addition, Polyethylene glycol trimethylnonyl ether has potential applications in drug delivery and other medical fields due to its ability to interact with and penetrate cell membranes.
    Polyethylene glycol trimethylnonyl ether
  • HY-W142692
    Dodecyl β-D-glucopyranoside

    		Biochemical Assay Reagents Others
    Dodecyl β-D-glucopyranoside is a non-ionic detergent and surfactant commonly used to solubilize and purify membrane proteins in biochemical research. Dodecyl β-D-glucopyranoside also interacts with bovine serum albumin (BSA) to quench its intrinsic fluorescence. The critical micelle concentration (CMC) of Dodecyl β-D-glucopyranoside (DG) and DG/BSA complex is 2.0 mM and 2.34 mM, respectively. Micelles can be formed in aqueous solutions above this concentration .
    Dodecyl β-D-glucopyranoside
  • HY-W127401
    Triethylene glycol monooctyl ether

    n-Octyltrioxyethylene

    		 Biochemical Assay Reagents Others
    Triethylene glycol monooctyl ether is a surfactant, C8E3 solubilizes membrane proteins.
    Triethylene glycol monooctyl ether
  • HY-W250171
    Octaethylene glycol monohexadecyl ether

    Polyoxyethylene (10) cetyl ether

    		 Biochemical Assay Reagents Others
    Octaethylene glycol monohexadecyl ether, is a nonionic surfactant commonly used in various industrial and research applications. Octaethylene glycol monohexadecyl ether belongs to the family of polyethylene glycol (PEG) ethers with a hydrophilic head and lipophilic tail, suitable for use in lotions, detergents and solubilizers. Octaethylene glycol monohexadecyl ether is particularly useful in the study of membrane proteins, where it is used to solubilize and stabilize proteins for structural analysis techniques. In addition, Octaethylene glycol monohexadecyl ether has the ability to interact with and penetrate cell membranes, so it has potential applications in drug delivery and other medical fields.
    Octaethylene glycol monohexadecyl ether
  • HY-W019895
    Tetradecylphosphocholine

    		Biochemical Assay Reagents Others
    Tetradecylphosphocholine is a zwitterionic surfactant that can be used as a detergent for membrane protein solubilization .
    Tetradecylphosphocholine
  • HY-15435R
    CHAPS (Standard)

    		Biochemical Assay Reagents Others
    CHAPS (Standard) is the analytical standard of CHAPS. This product is intended for research and analytical applications. CHAPS, a derivative of Cholic acid, is a zwitterionic detergent for solubilizing membrane proteins. CHAPS is used for stabilization of various protein-DNA complexes and can retain biochemical activity of proteins in solution .
    CHAPS (Standard)
  • HY-W016791
    Sodium pentanesulfonate, 98%

    Sodium pentane-1-sulfonate, 98%; NaPS, 98%

    		 Biochemical Assay Reagents Others
    Sodium pentanesulfonate, 98% (Sodium pentane-1-sulfonate, 98%; NaPS, 98%) is an anionic surfactant that can promote the solubility of proteins and membrane proteins. Sodium pentanesulfonate, 98% is a kind of biological materials or organic compounds that are widely used in life science research .
    Sodium pentanesulfonate, 98%
  • HY-W040218
    MEGA-8

    N-Octanoyl-N-methylglucamine

    		 Biochemical Assay Reagents Others
    MEGA-8 (N-Octanoyl-N-methylglucamine) is a nonionic sugar-based surfactant. MEGA-8 can gently solubilize membrane proteins without easily causing their denaturation. MEGA-8 is a commonly used reagent for the extraction and study of membrane proteins in biochemistry .
    MEGA-8
  • HY-136962
    ASB-14

    Amidosulfobetaine-14

    		 Biochemical Assay Reagents Others
    ASB-14 (Amidosulfobetaine-14) is a zwitterionic amidosulfobetaine surfactant with membrane protein solubilizing. ASB-14 can be used for the preparative extraction and solubilization of proteins .
    ASB-14
  • HY-121571
    Prallethrin

    		Insecticide Infection Cancer
    Prallethrin, a spatial mosquito repellent, is a non-fluorinated pyrethroid targeting lung surfactant proteins (SPs). prallethrin has vapor toxicity and can bind with the lung SPs by hydrogen and hydrophobic interactions, impairing functions of SPs. Prallethrin can be used for respiratory illness, pathogenic infections and malignancy research .
    Prallethrin
  • HY-P2207A
    Sinapultide TFA

    		Biochemical Assay Reagents Others
    Sinapultide TFA is a 21-amino-acid peptide that mimics the action of human surfactant protein-B (SP-B). Sinapultide TFA can be used for synthetic phospholipids surfactants improvement .
    Sinapultide TFA
  • HY-W838254
    1,2-Dipentadecanoyl-sn-glycero-3-phospho-(1'-rac-glycerol) sodium

    		PKC Endogenous Metabolite Others
    1,2-Dipentadecanoyl-sn-glycero-3-phospho-(1'-rac-glycerol) sodium functions as an activator for the protein kinase C family and is an anionic phospholipid found in mitochondrial and microsomal membranes, playing a crucial role in the composition of lung surfactant, particularly within the membranes of lamellar bodies in the lungs.
    1,2-Dipentadecanoyl-sn-glycero-3-phospho-(1'-rac-glycerol) sodium
  • HY-W250178
    Octaethylene glycol monodecyl ether

    		Biochemical Assay Reagents Others
    Octaethylene glycol monodecyl ether, is a nonionic surfactant commonly used in various industrial and research applications. It belongs to the family of polyethylene glycol (PEG) ethers with a hydrophilic head and lipophilic tail and is suitable for use in lotions, detergents and solubilizers. Octaethylene glycol monodecyl ether is particularly useful in the study of membrane proteins, where it is used to solubilize and stabilize proteins for structural analysis techniques. In addition, Octaethylene glycol monodecyl ether has the ability to interact with and penetrate cell membranes, so it has potential applications in drug delivery and other medical fields.
    Octaethylene glycol monodecyl ether
  • HY-W250179
    Hexaethylene glycol monohexadecyl ether

    Polyoxyethylene (6) cetyl ether

    		 Biochemical Assay Reagents Others
    Hexaethylene glycol monohexadecyl ether, is a nonionic surfactant belonging to the polyethylene glycol (PEG) ether family. It has a hydrophilic head and a lipophilic tail, which makes it suitable for a wide range of applications. Specifically, Hexaethylene glycol monohexadecyl ether is commonly used in membrane protein research, for solubilization and stabilization of proteins, and for structural analysis techniques such as X-ray crystallography and electron microscopy. Additionally, Hexaethylene glycol monohexadecyl ether is used in a variety of other industrial and research applications, including drug delivery systems, nanotechnology, and diagnostic analysis. Its unique properties make it ideal for facilitating interactions between molecules with different physicochemical properties.
    Hexaethylene glycol monohexadecyl ether
  • HY-W008974
    Sulfobetaine-18

    		Biochemical Assay Reagents Others
    3-(Dimethyl(octadecyl)ammonio)propane-1-sulfonate is a class of quaternary ammonium compounds. It is a surfactant and cationic detergent with amphiphilic properties and therefore useful in various industrial and biomedical applications. 3-(Dimethyl(octadecyl)ammonium)propane-1-sulfonate is commonly used as an emulsifier, solubilizer and antimicrobial agent in personal care products, detergents, textiles and pharmaceutical formulations. It is also used as a reagent in analytical chemistry, especially in the analysis of proteins and DNA.
    Sulfobetaine-18
  • HY-W284558S
    Sodium hexadecyl sulfate-d33

    		Isotope-Labeled Compounds Biochemical Assay Reagents Others
    Sodium hexadecyl sulfate-d33 is the deuterium labeled Sodium hexadecyl sulfate. Sodium hexadecyl sulfate is a long-chain anionic surfactant. Sodium hexadecyl sulfate can act as an interface-regulating substance to form a soft layer on the surface of carbon nanotubes, guide proteins to adsorb in the correct orientation with active sites facing outward through electrostatic interactions, and significantly enhance the activity of immobilized enzymes. Sodium hexadecyl sulfate can replace or supplement SDS (HY-Y0316) in capillary gel electrophoresis (CGE) .
    Sodium hexadecyl sulfate-d33
  • HY-W096997S
    Sodium octyl sulfate (SOS)-d17

    Sodium capryl sulfate-d17

    		 Isotope-Labeled Compounds Others
    Sodium octyl sulfate (SOS)-d17 (Sodium capryl sulfate-d17) is the deuterated analogue of Sodium octyl sulfate (SOS). Sodium octyl sulfate (Sodium capryl sulfate; SOS) is a medium‑chain anionic surfactant. Sodium octyl sulfate (SOS) can undergo strong hydrophobic interactions with serum albumins (such as human serum albumin (HSA) and bovine serum albumin (BSA)), while exhibiting weak interactions with other proteins including myoglobin and hemoglobin. As an environmental pollutant in freshwater ecosystems, Sodium octyl sulfate (SOS) can mimic interspecific pheromones released by Daphnia magna and induce the formation of multicellular colonies in green algae.
    Sodium octyl sulfate (SOS)-d17
  • HY-175413
    FTAC6

    		Biochemical Assay Reagents Others
    FTAC6 (C6F-TAC) is a lipophobic surfactant. FTAC6 does not solubilize biological membranes as a non-detergent and can substitute for detergents to keep membrane proteins soluble and improves stability after conventional solubilization. FTAC6 can be utilized in in vitro synthesis of membrane proteins .
    FTAC6
  • HY-185564
    F6OM

    		Biochemical Assay Reagents Others
    F6OM, a nonionic fluorinated octyl maltoside derivative, is a surfactant. F6OM readily interacts with and completely solubilizes phospholipid vesicles via a heterogeneous solubilization mechanism, without compromising membrane order at subsolubilizing concentrations. F6OM promotes bilayer insertion of an integral membrane enzyme in the absence of micelles to support functional refolding of integral membrane proteins. F6OM can be used for membrane-protein applications .
    F6OM
  • HY-108294R
    Nonaethylene glycol monododecyl ether (Standard)

    Nonaoxyethylene monododecyl ether (Standard)

    		 Biochemical Assay Reagents Reference Standards Others
    Nonaethylene glycol monododecyl ether (Standard) is the analytical standard of Nonaethylene glycol monododecyl ether (HY-108294). This product is intended for research and analytical applications. Nonaethylene glycol monododecyl ether (Nonaoxyethylene monododecyl ether) is a nonionic surfactant and polyethylene glycol (PEG) detergent that can be used to form initial coalesced O/W emulsion droplets, as well as for protein separation and purification .
    Nonaethylene glycol monododecyl ether (Standard)
  • HY-181647
    LasB-IN-3

    		Bacterial Elastase Infection
    LasB-IN-3 is a protease elastase (LasB) inhibitor of Pseudomonas aeruginosa with an IC50 value of 8.5 nM. LasB-IN-3 shows an IC50 of 58.9 nM for the Met128Val mutant. LasB-IN-3 binds to active sites of wild-type and Met128Val mutant LasB, coordinates zinc ions, forms hydrogen bonds and CH-π interactions, and inhibits LasB proteolytic activity. LasB-IN-3 increases survival rate in LasB-induced acute lung injury mice models. LasB-IN-3 can be used for the research of Pseudomonas aeruginosa infection .
    LasB-IN-3

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