Hel 13-5

Hel 13-5 (10 μM) forms an α-helical structure in aqueous buffer and retains α-helical structural characteristics in the presence of neutral, acidic, and soy lecithin liposomes at 10 μM concentration^[1].
Hel 13-5 (20 μM) exhibits near-complete hemolytic activity at an approximate concentration of 20 μM, with activity increasing in a concentration-dependent manner; this activity profile is shared with its derivative Hel 13-5D3^[1].
Hel 13-5 (0.01-0.025 molar fraction) alters the phase domain morphology of DPPG and DPPC/DPPG (4:1) Langmuir monolayers, reducing LC domain size in both systems, with more pronounced dispersion in DPPG/Hel 13-5 due to specific electrostatic interactions^[2].
Hel 13-5 (0.01-0.1 molar fraction) induces distinct phase behavior in DPPG Langmuir monolayers (forming two independent LC domain populations at X_Hel 13-5 = 0.01-0.05) due to specific electrostatic interactions, while only reducing LC domain size in DPPC/DPPG (4:1) monolayers due to dominant DPPC-DPPG miscibility^[2].
Hel 13-5 (0.1 molar fraction) forms larger, stabilized squeezed-out aggregates in DPPG LB films (retaining structure down to 35 mN m⁻¹ during expansion) due to specific electrostatic interactions, while forming smaller, rapidly respreading aggregates in DPPC/DPPG (4:1) and DPPC films^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.