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Results for "

Tannin

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (2) Bacterial (13) E1/E2/E3 Enzyme (1) Endogenous Metabolite (1) Glycosidase (1) JAK (2) Keap1-Nrf2 (2) Reactive Oxygen Species (ROS) (3) Reference Standards (1) β-catenin (2)
By Research Areas:	Cancer (3) Cardiovascular Disease (1) Infection (11) Inflammation/Immunology (20) Metabolic Disease (6) Neurological Disease (2)

Inhibitors & Agonists

Bibliotecas de Screening

Natural
Products

Cat. No.	Nombre del producto	Target	Áreas de investigación	Chemical Structure

HY-N0527

Pentagalloylglucose 10+ Cited Publications Penta-O-galloyl-β-D-glucose; 1,2,3,4,6-Pentagalloyl glucose	JAK Keap1-Nrf2 Apoptosis β-catenin Reactive Oxygen Species (ROS) E1/E2/E3 Enzyme	Neurological Disease Inflammation/Immunology Cancer
Pentagalloylglucose (Penta-O-galloyl-β-D-glucose) is an orally active gallic tannin compound and an inducer of apoptosis and autophagy. Pentagalloglucose induces cell apoptosis and autophagy through the GSK3β/β-catenin pathway. Pentagalloylglucose inhibits UBE2T-mediated p53 ubiquitination, upregulates p53, downregulates RRM1/RRM2 in pancreatic cancer organoids. Pentagalloglucose has antioxidant, anti mutagenic, anti-inflammatory, anticonvulsant, cardioprotective, anti allergic, cholesterol lowering, and anti-tumor activities .

HY-P2877

Tannase	Endogenous Metabolite	Others
Tannase is a tannin acyl hydrolase. Tannase catalyzes the hydrolysis of ester bonds in gallotannins, complex tannins and gallic acid esters to release gallic acid. Tannase plays a role in industrial production, including the manufacture of instant tea, beer, fruit juice, some wines, and the production of gallic acid .

HY-114760

Vanillic acid glucoside Vanillic acid 4-β-D-glucoside	Others	Others
Vanillic acid glucoside (Vanillic acid 4-β-D-glucoside), a hydrolyzable tannin, is isolated from the fruits of C. annuum as well as the leaves of various additional plants. Vanillic acid glucoside can be phytotoxic against different species.

HY-N16549

Procyanidin B3-3-O-gallate 3-O-Galloylprocyanidin B3	Others	Others
Procyanidin B3-3-O-gallate is a natural tannin compound found in Sanguisorba officinal .

HY-N0527R

Pentagalloylglucose (Standard) Penta-O-galloyl-β-D-glucose (Standard); 1,2,3,4,6-Pentagalloyl glucose (Standard)	Reference Standards JAK Keap1-Nrf2 Apoptosis β-catenin Reactive Oxygen Species (ROS)	Neurological Disease Inflammation/Immunology Cancer
Pentagalloylglucose (Standard) is the analytical standard of Pentagalloylglucose. This product is intended for research and analytical applications. Pentagalloylglucose (Penta-O-galloyl-β-D-glucose) is an orally active gallic tannin compound and an inducer of apoptosis and autophagy. Pentagalloglucose induces cell apoptosis and autophagy through the GSK3β/β-catenin pathway. Pentagalloylglucose inhibits UBE2T-mediated p53 ubiquitination, upregulates p53, downregulates RRM1/RRM2 in pancreatic cancer organoids. Pentagalloglucose has antioxidant, anti mutagenic, anti-inflammatory, anticonvulsant, cardioprotective, anti allergic, cholesterol lowering, and anti-tumor activities .

HY-N12500

1'-O-Methyl neochebulinate	Glycosidase	Others
1'-O-Methyl neochebulinate, hydrolyzable tannin, is an α-glucosidase inhibitor with IC₅₀ value of 59.5 μM, isolated from the fruits of Terminalia chebula Retz .

HY-N9862

Ethyl brevifolincarboxylate	Others	Others
Ethyl brevifolincarboxylate (compound 3) can be isolated from Quercus wutaishanica seeds .

HY-N17305

Nobotanin D	Others	Others
Nobotanin D (Compound 23) is a hydrolyzable tannin found in the fresh flowers of Camellia reticulata .

HY-N17351

3,6-Di-O-galloyl-D-glucopyranoside	Others	Others
3,6-Di-O-galloyl-D-glucopyranoside is a hydrolyzable tannin compound with astringent activity, found in the leaves of Myrtus communis .

HY-N19661

1-O-Caffeoyl-3-O-galloyl-β-D-glucopyranose		Inflammation/Immunology
1-O-Caffeoyl-3-O-galloyl-β-D-glucopyranose, a hydrolyzable tannin found in the rhizome of Balanophora harlandii, is a radical scavenger. 1-O-Caffeoyl-3-O-galloyl-β-D-glucopyranose scavenges DPPH (HY-N19661) radicals with a SC₅₀ value of 17.3 μM. 1-O-Caffeoyl-3-O-galloyl-β-D-glucopyranose can be used for antioxidant research .

HY-N17374

Laevigatin A	Others	Others
Laevigatin A (Compound 8) is a hydrolyzable tannin found in Rosa laevigata .

HY-N12220

Cinnamtannin D2	Others	Others
Cinnamtannin D2 (compound 13) is a cinnamon tannin isolated from Vaccinium vitis-idaea L .

HY-N19050

Acacia catechu extract	Bacterial	Infection Inflammation/Immunology
Acacia catechu extract is rich in bioactive components such as catechins, tannins, and flavonoids, and has astringent, anti-inflammatory, antioxidant, and antibacterial properties.

HY-N18646

Adiantum capillus-veneris extract	Others	Inflammation/Immunology
Adiantum capillus-veneris extract is rich in flavonoids and tannins, among other bioactive components, and has antioxidant and anti-inflammatory effects.

HY-N19082

Triphala extract	Others	Inflammation/Immunology
Tecomella undulata extract is a natural antioxidant, digestive aid, and potential anti-aging agent. It is rich in bioactive compounds such as flavonoids, polyphenols, tannins, and vitamin C.

HY-N18754

Saraca indica extract	Bacterial	Metabolic Disease Inflammation/Immunology
Saraca indica extract possesses anti-inflammatory, antioxidant, antibacterial, and antifungal properties; its primary active constituents include flavonoids, saponins, tannins, and alkaloids.

HY-N19074

Psidium guajava extract	Bacterial	Infection Inflammation/Immunology
Psidium guajava extract is rich in flavonoids (such as quercetin and kaempferol), tannins, vitamin C, carotenoids, and phenolic acids, which give it antioxidant, anti-inflammatory, antibacterial, and antiviral properties.

HY-N19077

Punica granatum rinds extract	Bacterial	Infection Inflammation/Immunology Cancer
Punica granatum rinds extract is rich in a variety of bioactive compounds, such as punicin, ellagic acid, tannins, and flavonoids, which give it powerful antioxidant, anti-inflammatory, antibacterial, and anticancer properties.

HY-N19068

Crataeva nurvula extract	Bacterial	Metabolic Disease
Crataeva nurvula extract is rich in active ingredients including flavonoids, saponins, triterpenoids, alkaloids, and tannins. Crataeva nurvula extract helps promote healthy kidney and bladder function.

HY-N19079

Rheum emodi extract	Others	Inflammation/Immunology
Rheum emodi extract has laxative, anti-inflammatory, and antioxidant properties. Its main active ingredients include anthraquinone compounds (such as emodin, chrysophanol, and aloe-emodin), flavonoids, and tannins.

HY-N18702

Pterocarpus marsupium extract	Others	Metabolic Disease Inflammation/Immunology
Pterocarpus marsupium extract is derived from the bark of the Indian rosewood tree. Its active ingredients include pterostilbene, santalin, flavonoids, and tannins, which give it antioxidant, anti-inflammatory, anti-diabetic, and cardioprotective properties.

HY-N19081

Terminalia belerica extract	Bacterial	Infection Inflammation/Immunology
Terminalia belerica extract is rich in various bioactive compounds, such as tannins, gallic acid, ellagic acid, chebulic acid, and various sugars including glucose and fructose. Terminalia belerica extract possesses antioxidant, antibacterial, anti-inflammatory, and hepatoprotective effects.

HY-N18727

Emblic extract	Bacterial	Infection Inflammation/Immunology
Emblic extract is derived from the fruit of a small tree native to India. Its active ingredients include vitamin C, tannins, flavonoids, polyphenols, and gallic acid, which give it powerful antioxidant, anti-inflammatory, and antibacterial properties.

HY-N18760

Vitex negundo extract	Bacterial	Infection Inflammation/Immunology
Vitex negundo extract is rich in bioactive compounds such as alkaloids, flavonoids, glycosides, volatile oils, triterpenoids, tannins, polyphenols, flavonoids, and iridoid glycosides. Vitex negundo extract possesses anti-inflammatory, antioxidant, antibacterial, and detoxifying properties.

HY-N18782

Quercus infectoria extract	Others	Inflammation/Immunology
Quercus infectoria extract is an extract from the fruit of the oak tree (Quercus infectoria) known for its powerful astringent, anti-inflammatory, and antioxidant properties. The active ingredients in Quercus infectoria extract include tannins (such as ellagic acid and gallic acid), flavonoids, and catechins.

HY-N18737

Phyllanthus niruri extract	Others	Inflammation/Immunology
Phyllanthus niruri extract, extracted from the whole plant of Phyllanthus niruri, is rich in bioactive compounds such as alkaloids, flavonoids, and tannins. Phyllanthus niruri extract has alkalizing properties, which may help prevent the formation of gallstones and acidic kidney stones.

HY-N18677

Rubia cordifolia extract	Bacterial	Infection Inflammation/Immunology
Rubia cordifolia extract, derived from the roots of the madder plant, is valued for its anti-inflammatory, antioxidant, antibacterial, and blood-purifying properties. Active ingredients in Rubia cordifolia extract include anthraquinone compounds (such as alizarin and alizarin red), flavonoids, and tannins.

HY-N17774

2,3,4,6-Tetragalloylglucose	Reactive Oxygen Species (ROS)	Others
2,3,4,6-Tetragalloylglucose is a hydrolyzable tannin with antioxidant activity, exhibiting DPPH free radical scavenging activity (IC₅₀=11.35 μM). 2,3,4,6-Tetragalloylglucose can be isolated from the endocarp of Juglans regia (walnut).

HY-N18732

Terminalia arjuna extract	Others	Cardiovascular Disease
Terminalia arjuna extract is a precious natural compound derived from the bark of the Terminalia arjuna tree, rich in bioactive components such as triterpenoids, flavonoids, tannins, and polyphenols. Terminalia arjuna extract has cardioprotective effects, helping to strengthen the heart muscle, lower cholesterol levels, stabilize blood pressure, and prevent thrombosis.

HY-N19039

Aerva lanata extract	Bacterial	Infection Metabolic Disease Inflammation/Immunology
Aerva Lanata Extract is a versatile herbal extract with a wide range of bioactive compounds and medicinal properties. Aerva Lanata Extract contains various phytochemicals such as flavonoids, terpenoids, alkaloids, tannins, and phenolic compounds. Aerva Lanata Extract shows significant antioxidant, antimicrobial, anti-cancer, anti-inflammatory, and anti-diabetic activities.

HY-N19065

Dalchini extract	Bacterial	Infection Inflammation/Immunology
Dalchini extract is rich in various bioactive compounds, including cinnamaldehyde, eugenol, tannins, polyphenols, and aromatic essential oils. Dalchini extract helps regulate blood sugar levels and improve insulin sensitivity. It also possesses anti-inflammatory, antioxidant, and antibacterial properties, which help enhance immune function, prevent infection, and reduce inflammation.

HY-N18676

Dolichos biflorus extract	Others	Metabolic Disease
Dolichos Biflorus Extract, derived from the seeds of the Dolichos biflorus plant (commonly known as horse gram), is a nutrient-dense herb widely used in Ayurvedic and traditional medicine for its numerous health benefits. Dolichos biflorus extract contains alkaloids, saponins, flavonoids, carbohydrates, proteins, and tannins. It is known for its digestive support, as it promotes healthy digestion, alleviates bloating, and helps with constipation, along with mild diuretic effects that aid detoxification by eliminating excess fluids and waste products from the body.

HY-N19069

Eugenia jambolana extract	Bacterial	Infection Metabolic Disease Inflammation/Immunology
Eugenia jambolana extract, commonly known as jamun or black plum, is derived from the fruit of the Eugenia jambolana tree, native to South Asia. The active compounds in jamun extract include anthocyanins, flavonoids, alkaloids, and tannins, which contribute to its antioxidant, anti-inflammatory, and antimicrobial properties. Jamun extract is most known for its blood sugar-lowering effects, making it popular in traditional medicine for managing diabetes. It is commonly used in supplements, traditional remedies, and skincare products due to its wide range of health benefits.

HY-N18656

Terminalia chebula extract	Bacterial	Infection
Terminalia chebula extract, derived from the fruit of the Terminalia chebula tree. Rich in bioactive compounds such as tannins, flavonoids, phenols, and organic acids like gallic acid and ellagic acid, this extract demonstrates a wide range of pharmacological activities. It acts as a natural laxative, supports digestive health, and exhibits potent antioxidant, anti-inflammatory, and antibacterial properties, effectively targeting various pathogenic bacteria, including Helicobacter pylori, Staphylococcus aureus, and Escherichia coli. Terminalia Chebula Extract also shows significant hepatoprotective effects, shielding the liver from damage through antioxidant and anti-inflammatory mechanisms. It has nephroprotective properties, alleviating renal dysfunction and enhancing kidney health by modulating inflammatory pathways. Additionally, the extract demonstrates neuroprotective activity, reducing neuronal damage and improving memory function. It has potential anti-diabetic effects, enhancing glucose uptake and reducing oxidative stress.

Cat. No.	Nombre del producto

HY-L021L

Natural Product-like Compound Library	45 compounds
Natural products are an attractive source with varied structures that exhibit potent biological activities, and desirable pharmacological profiles. The core scaffold of a natural product can also provide a biologically validated framework upon which to display diverse functional groups. Inspired by bioactive natural products, natural product-like compounds, occupying the same chemical space, are ideally suited to explore and to facilitate understanding of biological pathways. MCE provides a unique collection of 45 natural product-like compounds that are structurally like Steroids, Tannins, Flavonoids, Quinones, Isoquinolines, etc. This library is an important source of lead compounds for drug discovery.

Natural Product-like Compound Library

45 compounds

Natural products are an attractive source with varied structures that exhibit potent biological activities, and desirable pharmacological profiles. The core scaffold of a natural product can also provide a biologically validated framework upon which to display diverse functional groups. Inspired by bioactive natural products, natural product-like compounds, occupying the same chemical space, are ideally suited to explore and to facilitate understanding of biological pathways.

MCE provides a unique collection of 45 natural product-like compounds that are structurally like Steroids, Tannins, Flavonoids, Quinones, Isoquinolines, etc. This library is an important source of lead compounds for drug discovery.

Pentagalloylglucose 10+ Cited Publications Penta-O-galloyl-β-D-glucose; 1,2,3,4,6-Pentagalloyl glucose	Infection other families Classification of Application Fields Anti-aging Phenols Polyphenols Plants Disease Research Fields Source Classification	JAK Keap1-Nrf2 Apoptosis β-catenin Reactive Oxygen Species (ROS) E1/E2/E3 Enzyme
Pentagalloylglucose (Penta-O-galloyl-β-D-glucose) is an orally active gallic tannin compound and an inducer of apoptosis and autophagy. Pentagalloglucose induces cell apoptosis and autophagy through the GSK3β/β-catenin pathway. Pentagalloylglucose inhibits UBE2T-mediated p53 ubiquitination, upregulates p53, downregulates RRM1/RRM2 in pancreatic cancer organoids. Pentagalloglucose has antioxidant, anti mutagenic, anti-inflammatory, anticonvulsant, cardioprotective, anti allergic, cholesterol lowering, and anti-tumor activities .

Vanillic acid glucoside Vanillic acid 4-β-D-glucoside	Ketones, Aldehydes, Acids Thalictrum delavayi Franch. Plants Rhamnaceae Source Classification	Others
Vanillic acid glucoside (Vanillic acid 4-β-D-glucoside), a hydrolyzable tannin, is isolated from the fruits of C. annuum as well as the leaves of various additional plants. Vanillic acid glucoside can be phytotoxic against different species.

Procyanidin B3-3-O-gallate 3-O-Galloylprocyanidin B3	Structural Classification Sanguisorba officinalis Linn. Rosaceae Phenols Polyphenols Plants Source Classification	Others
Procyanidin B3-3-O-gallate is a natural tannin compound found in Sanguisorba officinal .

Pentagalloylglucose (Standard) Penta-O-galloyl-β-D-glucose (Standard); 1,2,3,4,6-Pentagalloyl glucose (Standard)	Structural Classification other families Phenols Polyphenols Plants Source Classification	Reference Standards JAK Keap1-Nrf2 Apoptosis β-catenin Reactive Oxygen Species (ROS)
Pentagalloylglucose (Standard) is the analytical standard of Pentagalloylglucose. This product is intended for research and analytical applications. Pentagalloylglucose (Penta-O-galloyl-β-D-glucose) is an orally active gallic tannin compound and an inducer of apoptosis and autophagy. Pentagalloglucose induces cell apoptosis and autophagy through the GSK3β/β-catenin pathway. Pentagalloylglucose inhibits UBE2T-mediated p53 ubiquitination, upregulates p53, downregulates RRM1/RRM2 in pancreatic cancer organoids. Pentagalloglucose has antioxidant, anti mutagenic, anti-inflammatory, anticonvulsant, cardioprotective, anti allergic, cholesterol lowering, and anti-tumor activities .

1'-O-Methyl neochebulinate	Combretaceae Phenols Polyphenols Terminalia chebula Retz. Plants Source Classification	Glycosidase
1'-O-Methyl neochebulinate, hydrolyzable tannin, is an α-glucosidase inhibitor with IC₅₀ value of 59.5 μM, isolated from the fruits of Terminalia chebula Retz .

Ethyl brevifolincarboxylate	Flavonoids Quercus mongolica Fischer ex Ledebour Plants Fagaceae Other Flavonoids Source Classification	Others
Ethyl brevifolincarboxylate (compound 3) can be isolated from Quercus wutaishanica seeds .

Nobotanin D	Structural Classification Phenols Polyphenols Camellia reticulata Lindl. Plants Source Classification Theaceae	Others
Nobotanin D (Compound 23) is a hydrolyzable tannin found in the fresh flowers of Camellia reticulata .

3,6-Di-O-galloyl-D-glucopyranoside	Structural Classification Punica granatum L. Phenols Polyphenols Punicaceae Plants Saccharides Monosaccharides Source Classification	Others
3,6-Di-O-galloyl-D-glucopyranoside is a hydrolyzable tannin compound with astringent activity, found in the leaves of Myrtus communis .

1-O-Caffeoyl-3-O-galloyl-β-D-glucopyranose	Structural Classification Balanophora harlandii Hook. f. Phenols Polyphenols Plants Balanophoraceae Source Classification
1-O-Caffeoyl-3-O-galloyl-β-D-glucopyranose, a hydrolyzable tannin found in the rhizome of Balanophora harlandii, is a radical scavenger. 1-O-Caffeoyl-3-O-galloyl-β-D-glucopyranose scavenges DPPH (HY-N19661) radicals with a SC₅₀ value of 17.3 μM. 1-O-Caffeoyl-3-O-galloyl-β-D-glucopyranose can be used for antioxidant research .

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