Procyanidin B3-3-O-gallate
Procyanidin B3-3-O-gallate (3-O-Galloylprocyanidin B3) is a selective mammalian DNA polymerase α inhibitor, with a calf DNA polymerase α IC50 of 0.26 μM. Procyanidin B3-3-O-gallate scavenges DPPH radicals. Procyanidin B3-3-O-gallate can be used for research on oxidative stress and inflammatory diseases[1].
For research use only. We do not sell to patients.
- CAS No.: 86631-41-6
- Formula: C37H30O16
- Molecular Weight:730.62
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All DNA/RNA Synthesis Isoforms
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Biological Activity
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DNA Polymerase 0.26 μM (IC50) |
Procyanidin B3-3-O-gallate (Compound 2) inhibits UV-induced lipid peroxide formation with an IC50 of 57 μM[1].
Procyanidin B3-3-O-gallate scavenges DPPH radicals with an SC50 of 3.2 μM[1].
Procyanidin B3-3-O-gallate potently inhibits calf thymus DNA polymerase α with an IC50 of 0.26 μM, while showing no inhibition of recombinant rat DNA polymerase β at concentrations >100 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 86631-41-6
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Molecular Weight 730.62
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Formula C37H30O16
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SMILES
O=C(C1=CC(O)=C(C(O)=C1)O)O[C@H]2[C@H](C3=C4C(C[C@@H]([C@@H](C5=CC(O)=C(C=C5)O)O4)O)=C(C=C3O)O)C6=C(O)C=C(O)C=C6O[C@@H]2C7=CC(O)=C(C=C7)O
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Synonyms
3-O-Galloylprocyanidin B3
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Procyanidin B3-3-O-gallate Related Classifications
HY-N16549 Related Classifications
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- Procyanidin B3-3-O-gallate
- 86631-41-6
- 3-O-Galloylprocyanidin B3
- DNA/RNA Synthesis
- Reactive Oxygen Species (ROS)
- DNA polymerase β
- calf DNA polymerase α
- DPPH radicals
- calf thymus DNA polymerase α
- mammalian DNA polymerase α
- free radical scavenger
- UV-induced lipid peroxide formation
- recombinant rat DNA polymerase β
- Inhibitor
- inhibitor
- inhibit