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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
31 Results for "
boronic acid inhibitors
" in MedChemExpress (MCE) Product Catalog:
Products (31)
31 Results for "boronic acid inhibitors" in MCE Product Catalog:
42
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Vaborbactam (RPX7009) is a cyclic boronic acid pharmacophore β-lactamase inhibitor.
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Taniborbactam (VNRX-5133) is a reversible and selective boronic acid-containing pan-spectrum β-lactamase inhibitor with IC50s of 8-530 nM. Taniborbactam has IC50s of 30 nM, 32 nM, 42 nM, 20 nM for KPC-2, AmpC, OXA-48, and VIM-2. Taniborbactam is against Gram-negative bacteria .
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19 Cited Publications
Synonyms: VNRX-5133 hydrochloride
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Taniborbactam hydrochloride (VNRX-5133 hydrochloride) is a reversible and selective boronic acid-containing pan-spectrum β-lactamase inhibitor with IC50s of 8-530 nM. Taniborbactam hydrochloride has IC50s of 30 nM, 32 nM, 42 nM, 20 nM for KPC-2, AmpC, OXA-48, and VIM-2. Taniborbactam hydrochloride is against Gram-negative bacteria .
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6 Cited Publications
Xeruborbactam disodium is a potent, ultra-broad-spectrum boronic acid beta-lactamase inhibitor. Xeruborbactam disodium inhibits key serine and metallo beta-lactamases at a nano molar range .
1
1 Cited Publications
Cat. No.: HY-23524
CAS No.: 346656-34-6
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HSL-IN-3 is a HSL inhibitor. HSL-IN-3 serves as an important intermediate for the synthesis of PARP-1 inhibitors. HSL-IN-3 can be used in studies related to lipid metabolism .
Cat. No.: HY-111521
CAS No.: 2031124-72-6
Synonyms: Carbavance
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Meropenem-vaborbactam (Carbavance) is a Carbapenem Antibiotic and Boronic acid-based beta-lactamase inhibitor, is a fixed-dose combination product with potent in vitro activity against Enterobacteriaceae that are Klebsiella pneumoniae carbapenemase producers. Meropenem-vaborbactam exhibits activity against Pseudomonas aeruginosa isolates , with an MIC50 of 0.5 μg/mL and an MIC90 of 8 μg/mL .
Cat. No.: HY-W001242
CAS No.: 903550-26-5
Cat. No.: HY-32951
CAS No.: 401815-98-3
Cat. No.: HY-I0314
CAS No.: 269410-08-4
Cat. No.: HY-136069
CAS No.: 2170834-63-4
Xeruborbactam is a potent, ultra-broad-spectrum boronic acid beta-lactamase inhibitor. Xeruborbactam inhibits key serine and metallo beta-lactamases at a nano molar range .
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SX-517 is a dual CXCR2/1 antagonist, containing boronic acid. SX-517 inhibits CXCL1-induced Ca 2+ flux (IC50=38 nM), and antagonizes CXCL8-induced [(35)S]GTPγS binding (IC50=60 nM) and ERK1/2 phosphorylation. SX-517 has significant ability for inflammation suppression, in both humanized polymorphonuclear (PMN) cells and in murine model .
Cat. No.: HY-32955
CAS No.: 444120-91-6
Cat. No.: HY-137144
CAS No.: 1853279-29-4
Synonyms: ZB716
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Fulvestrant-3-boronic acid is an orally active ERα inhibitor, which binds to ERα competitively (IC50 = 4.1 nM) and effectively degrades ERα in breast cancer cells .
Cat. No.: HY-W002734
CAS No.: 87199-18-6
Synonyms: 3-Hydroxybenzeneboronic acid
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(3-Hydroxyphenyl)boronic acid (3-Hydroxybenzeneboronic acid) is a drug intermediate that can be used for the synthesis of 17β-hydroxysteroid dehydrogenase type 1 inhibitors .
Cat. No.: HY-32952
CAS No.: 351019-18-6
Synonyms: 6-Fluoropyridine-3-boronic acid
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2-Fluoropyridine-5-boronic acid (6-Fluoropyridine-3-boronic acid) is a fatty acid amide hydrolase (FAAH) inhibitor with an IC50 of 10 μM. 2-Fluoropyridine-5-boronic acid is applicable to research related to inflammation and pain .
Cat. No.: HY-78197
CAS No.: 832114-00-8
Cat. No.: HY-136070
CAS No.: 2170834-56-5
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Xeruborbactam bis-acetoxy methyl ester is a boronic acid β-lactamase inhibitor, exacted from WO2018005662A1, compound 42 .
Cat. No.: HY-136071
CAS No.: 2170834-57-6
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Xeruborbactam methoxy acetoxy methy ester is a boronic acid β-lactamase inhibitor, exacted from WO2018005662A1, compound 43 .
Cat. No.: HY-W002463
CAS No.: 63503-60-6
Cat. No.: HY-161998
CAS No.: 1203704-26-0
Urease-IN-16 (compound 4e) is a urease inhibitor, with an IC50 value of 132 μmol/L. Urease-IN-16 can coordinate with the nickel atom through the oxygen atoms of carbonyl or boronic acid groups. Urease-IN-16 shows great potential as an additive in the development of efficient fertilizers and medical applications .
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
