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  3. QPX7728

QPX7728 

Cat. No.: HY-136069
Handling Instructions

QPX7728 is a potent, ultra-broad-spectrum boronic acid beta-lactamase inhibitor. QPX7728 inhibits key serine and metallo beta-lactamases at a nano molar range.

For research use only. We do not sell to patients.

QPX7728 Chemical Structure

QPX7728 Chemical Structure

CAS No. : 2170834-63-4

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Description

QPX7728 is a potent, ultra-broad-spectrum boronic acid beta-lactamase inhibitor. QPX7728 inhibits key serine and metallo beta-lactamases at a nano molar range[1].

In Vitro

QPX7728 is a potent inhibitor of Class D carbapenemases from A. baumannii[1].
QPX7728 is minimally affected by the activity of major MDR efflux pumps from P. aeruginosa, representing a significant improvement over the earlier generation boronate beta-lactamase inhibitor (BLI) vaborbactam[1].
The ultra-broad-spectrum beta-lactamase inhibition profile combined with enhancement of the activity of multiple beta-lactam antibiotics with varying sensitivity to the intrinsic resistance mechanisms of efflux and permeability indicate QPX7728 is a useful inhibitor for use with multiple beta-lactam antibiotics[1].

Molecular Weight

221.98

Formula

C₁₀H₈BFO₄

CAS No.

2170834-63-4

SMILES

FC1=C(C(O)=O)C2=C(C=C1)[[email protected]@H]3[[email protected]@H](C3)B(O)O2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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  • Molarity Calculator

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

QPX7728QPX 7728QPX-7728BacterialMDReffluxEnterobacteriaceaePseudomonasaeruginosaAcinetobacterbaumanniiantibioticserinemetalloInhibitorinhibitorinhibit

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QPX7728
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