2170834-63-4
2170834-63-4
Chemical Structure
Xeruborbactam
- CAS No.: 2170834-63-4
- Formula:C10H8BFO4
- Molecular Weight:221.98
IUPAC Name: (1aR,7bS)-5-fluoro-2-hydroxy-1,1a,2,7b-tetrahydrobenzo[e]cyclopropa[c][1,2]oxaborinine-4-carboxylic acid
InChIKey: KOHUFVUIYUCFNG-PHDIDXHHSA-N
SMILES: FC1=C(C(O)=O)C2=C(C=C1)[C@@H]3[C@@H](C3)B(O)O2
Biological Activity: Xeruborbactam is a potent, ultra-broad-spectrum boronic acid beta-lactamase inhibitor. Xeruborbactam inhibits key serine and metallo beta-lactamases at a nano molar range[1].
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Xeruborbactam | Xeruborbactam is a potent, ultra-broad-spectrum boronic acid beta-lactamase inhibitor. Xeruborbactam inhibits key serine and metallo beta-lactamases at a nano molar range. | |||||||||||||||||||||
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References
- [1]. Lomovskaya O, et al, The Impact of Intrinsic Resistance Mechanisms on Potency of QPX7728, a New Ultra-Broad-Spectrum Beta-lactamase Inhibitor of Serine and Metallo Beta-Lactamases in Enterobacteriaceae, Pseudomonas aeruginosa, and Acinetobacter baumannii. Antimicrob Agents Chemother. 2020 Mar 30. pii: AAC.00552-20. [Content Brief]
Keywords
