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Pathways Recommended:	Stem Cell/Wnt Cell Cycle/DNA Damage

Results for "

cell surface glycans

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Acyltransferase (2) Apoptosis (1) Biochemical Assay Reagents (2) Drug Derivative (2) Galectin (2) OGT (2)
By Research Areas:	Cancer (2) Infection (1) Metabolic Disease (2)
Oligonucleotides:	Nucleoside Analogs (1)

Inhibitors & Agonists

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Oligonucleotides

Targets Recommended: Programmed Cell Death 4 (PDCD4) Itk TOPK NAMPT ALCAM/CD166 GDNF Receptor BCL6 Tim3 VISTA BMI1

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-119738

OSMI-1 40+ Cited Publications	OGT Acyltransferase	Metabolic Disease
OSMI-1 is a cell-permeable O-GlcNAc transferase (OGT) inhibitor with an IC₅₀ value of 2.7 μM. OSMI-1 inhibits protein O-linked N-acetylglucosamine (O-GlcNAcylation) in several mammalian cell lines without qualitatively altering cell surface N- or O-linked glycans .

HY-N10531

Lewis a trisaccharide Lewis a	Others	Others
Lewis a trisaccharide (Lewis a) is a trisaccharide that has been found to be present in the glycan structures of spermatozoa. Lewis a trisaccharide also is a major component of the glycan structures on the surface of HL-60 cells .

HY-177892A

UDP-2-alkyne-GlcNAc disodium	Drug Derivative Biochemical Assay Reagents	Others
UDP-2-alkyne-GlcNAc disodium (Compound 3) is a UDP-GlcNAc (HY-148596) derivative. UDP-2-alkyne-GlcNAc disodium can be used for the remodeling of cell surface glycans .

HY-119738A

(Rac)-OSMI-1	OGT Acyltransferase	Metabolic Disease
(Rac)-OSMI-1 is the racemate of OSMI-1. OSMI-1 is a cell-permeable O-GlcNAc transferase (OGT) inhibitor with an IC₅₀ value of 2.7 μM. OSMI-1 inhibits protein O-linked N-acetylglucosamine (O-GlcNAcylation) in several mammalian cell lines without qualitatively altering cell surface N- or O-linked glycans .

HY-N12918

Lewis X tetrasaccharide	Others	Infection
Lewis X tetrasaccharide is a cell surface glycan that can be used for diagnosis of microbial infections.

HY-P10010

DB21, Galectin-1 Antagonist	Galectin	Cancer
DB21, Galectin-1 Antagonist is a dibenzofuran conjugated peptidomimetic that acts as an allosteric inhibitor of galectin-1 (GAL1)binding to cell surface glycans. DB21, Galectin-1 Antagonis increases inhibition of angiogenesis and tumour growth in melanoma, lung adenocarcinoma and ovarian cancer models .

HY-177892

UDP-2-alkyne-GlcNAc	Drug Derivative Biochemical Assay Reagents	Others
UDP-2-alkyne-GlcNAc (Compound 3) is a UDP-GlcNAc (HY-148596) derivative. UDP-2-alkyne-GlcNAc can be used for the remodeling of cell surface glycans .

HY-181648

Gal-1-IN-1	Galectin Apoptosis	Cancer
Gal-1-IN-1 is a potent and selective human galectin-1 (hGal-1) inhibitor with a K_i of 0.022 μM. Gal-1-IN-1 blocks hGal-1 binding to tumor cells and suppresses human galectin-1-induced pre-apoptosis state. Gal-1-IN-1 reduces hGal-1-expressing cancer cell viability. Gal-1-IN-1 can be used for the research of breast cancer .

Cat. No.	Product Name	Target	Research Area

HY-P10010

DB21, Galectin-1 Antagonist	Galectin	Cancer
DB21, Galectin-1 Antagonist is a dibenzofuran conjugated peptidomimetic that acts as an allosteric inhibitor of galectin-1 (GAL1)binding to cell surface glycans. DB21, Galectin-1 Antagonis increases inhibition of angiogenesis and tumour growth in melanoma, lung adenocarcinoma and ovarian cancer models .

HY-P11710

Phos-FLAG	Peptides	Others
Phos-FLAG is a phosphorylated FLAG peptide. Phos-FLAG can undergo a Staudinger-like linkage reaction with azide groups metabolized into cell surface glycans and organ glycoproteins, enabling quantitative analysis of the presence of cell surface azides. Phos-FLAG can detect azide-labeled glycans in isolated cell and organ lysates .

Lewis a trisaccharide Lewis a	Structural Classification Polysaccharides Animals Classification of Application Fields Other Diseases Disease Research Fields Saccharides	Others
Lewis a trisaccharide (Lewis a) is a trisaccharide that has been found to be present in the glycan structures of spermatozoa. Lewis a trisaccharide also is a major component of the glycan structures on the surface of HL-60 cells .

Lewis X tetrasaccharide	Polysaccharides Animals Saccharides Source Classification	Others
Lewis X tetrasaccharide is a cell surface glycan that can be used for diagnosis of microbial infections.

Cat. No.	Product Name		Classification

HY-177892A

UDP-2-alkyne-GlcNAc disodium		Nucleoside Analogs
UDP-2-alkyne-GlcNAc disodium (Compound 3) is a UDP-GlcNAc (HY-148596) derivative. UDP-2-alkyne-GlcNAc disodium can be used for the remodeling of cell surface glycans .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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