DB21, Galectin-1 Antagonist
DB21, Galectin-1 Antagonist is a dibenzofuran conjugated peptidomimetic that acts as an allosteric inhibitor of galectin-1 (GAL1)binding to cell surface glycans. DB21, Galectin-1 Antagonis increases inhibition of angiogenesis and tumour growth in melanoma, lung adenocarcinoma and ovarian cancer models.
For research use only. We do not sell to patients.
- CAS No.: 1623027-80-4
- Formula: C83H136N18O19
- Molecular Weight:1690.08
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Galectin Isoforms
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Biological Activity
Chemical Information
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CAS No. 1623027-80-4
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Molecular Weight 1690.08
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Formula C83H136N18O19
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SMILES
O=C(N[C@@H]([C@@H](C)CC)C(N[C@@H](C(C)C)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@@H](CC(N)=O)C(N[C@@H](C)C(O)=O)=O)=O)=O)=O)=O)[C@H]([C@@H](C)CC)NC(CCC1=CC=CC2=C1OC3=C2C=CC=C3CCNC([C@H](CC(C)C)NC([C@@H](NC([C@@H](CCC)NC([C@H](CCC(N)=O)NC([C@H](C(C)C)NC([C@H](CO)N)=O)=O)=O)=O)CCCCN)=O)=O)=O
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Sequence
Ser-Val-Gln-{Nva}-Lys-Leu-{DBF}-Ile-Ile-Val-Lys-Leu-Asn-Ala
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Sequence Shortening
SVQ-{Nva}-KL-{DBF}-IIVKLNA
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)