1623027-80-4
Chemical Structure
DB21, Galectin-1 Antagonist
- CAS No.: 1623027-80-4
- Formula:C83H136N18O19
- Molecular Weight:1690.08
InChIKey: UHQNWDPLPFFABA-LENZRKJMSA-N
SMILES: O=C(N[C@@H]([C@@H](C)CC)C(N[C@@H](C(C)C)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@@H](CC(N)=O)C(N[C@@H](C)C(O)=O)=O)=O)=O)=O)=O)[C@H]([C@@H](C)CC)NC(CCC1=CC=CC2=C1OC3=C2C=CC=C3CCNC([C@H](CC(C)C)NC([C@@H](NC([C@@H](CCC)NC([C@H](CCC(N)=O)NC([C@H](C(C)C)NC([C@H](CO)N)=O)=O)=O)=O)CCCCN)=O)=O)=O
Biological Activity: DB21, Galectin-1 Antagonist is a dibenzofuran conjugated peptidomimetic that acts as an allosteric inhibitor of galectin-1 (GAL1)binding to cell surface glycans. DB21, Galectin-1 Antagonis increases inhibition of angiogenesis and tumour growth in melanoma, lung adenocarcinoma and ovarian cancer models[1].
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DB21, Galectin-1 Antagonist | DB21, Galectin-1 Antagonist is a dibenzofuran conjugated peptidomimetic that acts as an allosteric inhibitor of galectin-1 (GAL1)binding to cell surface glycans. DB21, Galectin-1 Antagonis increases inhibition of angiogenesis and tumour growth in melanoma, lung adenocarcinoma and ovarian cancer models. | |||||||||||||||||||||
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