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Results for "

cephalosporin β-lactam antibiotic

" in MedChemExpress (MCE) Product Catalog:

30

Inhibitors & Agonists

2

Peptides

2

Isotope-Labeled Compounds

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-108913
    Nitrocefin
    2 Publications Verification

    		 Beta-lactamase Antibiotic Bacterial Infection
    Nitrocefin is a highly activated, chromogenic cephalosporin derivative. Nitrocefin is a chromogenic β-lactamase substrate. Nitrocefin undergoes a distinctive color change from yellow to red as the amide bond in the β-lactam ring is hydrolyzed by β-lactamase. Nitrocefin is used in competitive inhibition studies in developmental work on β-lactamase-resistant antibiotics .
    Nitrocefin
  • HY-B0712B
    Ceftriaxone sodium salt
    Maximum Cited Publications
    16 Publications Verification

    Ro 13-9904

    		 Antibiotic GSK-3 Bacterial Aurora Kinase Infection Inflammation/Immunology Cancer
    Ceftriaxone sodium salt (Ro 13-9904) is a broad spectrum β-lactam third-generation cephalosporin antibiotic, which has good antibacterial activity against a variety of gram-negative and positive bacteria. Ceftriaxone sodium salt is a covalent inhibitor of GSK3β with IC50 value of 0.78 μM. Ceftriaxone sodium salt is an inhibitor of Aurora B. Ceftriaxone sodium salt has anti-inflammatory, antitumor and antioxidant activities. Ceftriaxone sodium salt can be used in the study of bacterial infections and meningitis .
    Ceftriaxone sodium salt
  • HY-B0712
    Ceftriaxone
    Maximum Cited Publications
    16 Publications Verification

    Ro 13-9904 free acid

    		 Bacterial Antibiotic GSK-3 Aurora Kinase Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
    Ceftriaxone (Ro 13-9904 free acid) is a broad spectrum β-lactam third-generation cephalosporin antibiotic, which has good antibacterial activity against a variety of gram-negative and positive bacteria. Ceftriaxone is a covalent inhibitor of GSK3β with IC50 value of 0.78 μM. Ceftriaxone is an inhibitor of Aurora B. Ceftriaxone has anti-inflammatory, antitumor and antioxidant activities. Ceftriaxone can be used in the study of bacterial infections and meningitis .
    Ceftriaxone
  • HY-B0712A
    Ceftriaxone sodium hydrate
    Maximum Cited Publications
    16 Publications Verification

    Ro 13-9904 sodium hydrate

    		 Bacterial Antibiotic GSK-3 Aurora Kinase Infection Cancer
    Ceftriaxone sodium hydrate (Ro 13-9904 sodium hydrate) is a broad spectrum β-lactam third-generation cephalosporin antibiotic, which has good antibacterial activity against a variety of gram-negative and positive bacteria. Ceftriaxone sodium hydrate is a covalent inhibitor of GSK3β with IC50 value of 0.78 μM. Ceftriaxone sodium hydrate is an inhibitor of Aurora B. Ceftriaxone sodium hydrate has anti-inflammatory, antitumor and antioxidant activities. Ceftriaxone sodium hydrate can be used in the study of bacterial infections and meningitis .
    Ceftriaxone sodium hydrate
  • HY-B1252
    Cefalonium

    		Antibiotic Bacterial Infection Inflammation/Immunology
    Cefalonium is the first-generation β-lactam cephalosporin antibiotic that is widely used to research bovine mastitis caused by Gram-positive bacteria including staphylococci .
    Cefalonium
  • HY-B0186B
    Cefoselis sulfate

    FK-037

    		 Bacterial Antibiotic Infection
    Cefoselis sulfate (FK-037), the fourth gen-eration of cephalosporin, is a β-lactam antibiotic. Cefoselis sulfate exhibits good activity against a wide range of Gram-positive and Gram-negative organisms. Cefoselis sulfate penetrates the blood-brain barrier .
    Cefoselis sulfate
  • HY-B1275
    Cephalothin sodium
    3 Publications Verification

    Cefalotin sodium

    		 Beta-lactamase Bacterial Antibiotic Infection
    Cephalothin (Cephalotin) sodium is a semi-synthetic cephalosporin antibiotic and beta-lactam antibiotic. Cephalothin inhibits class C β-lactamase AmpC, with an Ki of 0.32 µM. Cephalothin sodium binds to penicillin-binding proteins, interfering with the cross-linking of peptidoglycan in the cell wall and thus hindering the normal synthesis of the bacterial cell wall. Cephalothin sodium shows antibacterial activity against a variety of bacteria. Cephalothin sodium can be used in hematological and nephrotoxicity studies .
    Cephalothin sodium
  • HY-B1275A
    Cephalothin
    3 Publications Verification

    Cephalotin

    		 Beta-lactamase Bacterial Antibiotic Infection Cardiovascular Disease
    Cephalothin (Cephalotin) is a semi-synthetic cephalosporin antibiotic and beta-lactam antibiotic. Cephalothin inhibits class C β-lactamase AmpC, with an Ki of 0.32 µM. Cephalothin binds to penicillin-binding proteins, interfering with the cross-linking of peptidoglycan in the cell wall and thus hindering the normal synthesis of the bacterial cell wall. Cephalothin shows antibacterial activity against a variety of bacteria. Cephalothin can be used in hematological and nephrotoxicity studies .
    Cephalothin
  • HY-P3519
    ACV Tripeptide

    		Drug Intermediate Infection
    ACV Tripeptide, a tripeptide, is the first dedicated intermediate in the biosynthetic pathway leading to the penicillin and cephalosporin classes of β-lactam natural products in bacteria and fungi. ACV Tripeptide is is synthesized nonribosomally by the ACV synthetase (ACVS) enzyme, which is encoded by the 11 kb The pchAB gene encodes this enzyme. ACV Tripeptide can be used for the biosynthesis of β-lactam antibiotics .
    ACV Tripeptide
  • HY-B1682A
    Loracarbef hydrate

    		Antibiotic Bacterial Infection
    Loracarbef hydrate, a cephalosporin antibiotic, is an orally active second-generation synthetic beta-lactam antibiotic of the carbacephem class .
    Loracarbef hydrate
  • HY-16137
    Cefaloglycin

    Cephaloglycin

    		 Bacterial Infection
    Cefaloglycin (Cephaloglycin) is an orally active nephrotoxic β-lactam cephalosporin antibiotic with antibacterial activity. Cefaloglycin is activity against Gram-Positive cocci other than enterococci. Cefaloglycin is toxic to mitochondrial substrate uptake and respiration .
    Cefaloglycin
  • HY-W764182
    Cephalosporinase,bacillus

    		Bacterial Infection
    Cephalosporinase, bacillus are enzymes produced by bacillus, inactivated and degrade the ability of the cephalosporin class of antibiotics. Cephalosporins are a class of β-lactam antibiotics that are widely used to study bacterial infections .
    Cephalosporinase,bacillus
  • HY-B0712R
    Ceftriaxone (Standard)

    Ro 13-9904 free acid (Standard)

    		 Reference Standards Bacterial Antibiotic GSK-3 Aurora Kinase Infection Inflammation/Immunology Cancer
    Ceftriaxone (Standard) is the analytical standard of Ceftriaxone. This product is intended for research and analytical applications. Ceftriaxone (Ro 13-9904 free acid) is a broad spectrum β-lactam third-generation cephalosporin antibiotic, which has good antibacterial activity against a variety of gram-negative and positive bacteria. Ceftriaxone is a covalent inhibitor of GSK3β with IC50 value of 0.78 μM. Ceftriaxone is an inhibitor of Aurora B. Ceftriaxone has anti-inflammatory, antitumor and antioxidant activities. Ceftriaxone can be used in the study of bacterial infections and meningitis[1][2][3][4][5][6][7].
    Ceftriaxone (Standard)
  • HY-B1252A
    Cefalonium hydrate

    		Antibiotic Bacterial Infection Inflammation/Immunology
    Cefalonium hydrate is the first-generation β-lactam cephalosporin antibiotic that is widely used to research bovine mastitis caused by Gram-positive bacteria including staphylococci .
    Cefalonium hydrate
  • HY-B1682
    Loracarbef

    		Antibiotic Bacterial Infection
    Loracarbef, a cephalosporin antibiotic, is an orally active second-generation synthetic beta-lactam antibiotic of the carbacephem class .
    Loracarbef
  • HY-B0186
    Cefoselis

    		Bacterial Antibiotic Infection
    Cefoselis, the fourth gen-eration of cephalosporin, is a β-lactam antibiotic. Cefoselis exhibits good activity against a wide range of Gram-positive and Gram-negative organisms. Cefoselis penetrates the blood-brain barrier .
    Cefoselis
  • HY-W140760
    Ceftriaxone sodium

    		Antibiotic Infection Inflammation/Immunology Cancer
    Ceftriaxone sodium is a versatile broad-spectrum β-lactam tertiary cephalosporin antibiotic that exhibits anti-inflammatory, antitumor, antibacterial, and antioxidant properties, and functions as a covalent inhibitor of GSK3β and Aurora B, making it valuable in research related to sepsis and infective endocarditis.
    Ceftriaxone sodium
  • HY-B1252R
    Cefalonium (Standard)

    		Reference Standards Antibiotic Bacterial Infection Inflammation/Immunology
    Cefalonium (Standard) is the analytical standard of Cefalonium. This product is intended for research and analytical applications. Cefalonium is the first-generation β-lactam cephalosporin antibiotic that is widely used to research bovine mastitis caused by Gram-positive bacteria including staphylococci .
    Cefalonium (Standard)
  • HY-B1252AS
    Cefalonium-d4 hydrate

    		Isotope-Labeled Compounds Infection
    Cefalonium-d4 (hydrate) is the deuterium labeled Cefalonium (hydrate)(HY-B1252A).Cefalonium hydrate is the first-generation β-lactam cephalosporin antibiotic that is widely used to research bovine mastitis caused by Gram-positive bacteria including staphylococci .
    Cefalonium-d4 hydrate
  • HY-B0712S1
    Ceftriaxone-13C2,d3 triethylammonium salt

    Ro 13-9904-13C2,d32 triethylammonium salt

    		 Antibiotic Aurora Kinase GSK-3 Bacterial Isotope-Labeled Compounds Infection Inflammation/Immunology Cancer
    Ceftriaxone-13C2,d3 triethylammonium salt is 13C and deuterated labeled Ceftriaxone (HY-B0712). Ceftriaxone (Ro 13-9904 free acid) is a broad spectrum β-lactam third-generation cephalosporin antibiotic, which has good antibacterial activity against a variety of gram-negative and positive bacteria. Ceftriaxone is a covalent inhibitor of GSK3β with IC50 value of 0.78 mM. Ceftriaxone is an inhibitor of Aurora B. Ceftriaxone has anti-inflammatory, antitumor and antioxidant activities. Ceftriaxone can be used in the study of bacterial infections and meningitis .
    Ceftriaxone-13C2,d3 triethylammonium salt
  • HY-107330
    (6R,7S)-Cefminox sodium heptahydrate
    1 Publications Verification

    		 Antibiotic Others
    (6R,7S)-Cefminox sodium heptahydrate is an isomer of Cefminox sodium heptahydrate. Cefminox sodium heptahydrate is a β-lactam cephalosporin antibiotic, which exhibits a broad spectrum of antibacterial activity .
    (6R,7S)-Cefminox sodium heptahydrate
  • HY-P3519A
    ACV Tripeptide TFA

    		Drug Intermediate Infection
    ACV Tripeptide TFA, a tripeptide, is the first dedicated intermediate in the biosynthetic pathway leading to the penicillin and cephalosporin classes of β-lactam natural products in bacteria and fungi. ACV Tripeptide TFA is is synthesized nonribosomally by the ACV synthetase (ACVS) enzyme, which is encoded by the 11 kb The pchAB gene encodes this enzyme. ACV Tripeptide TFA can be used for the biosynthesis of β-lactam antibiotics .
    ACV Tripeptide TFA
  • HY-B0186A
    Cefoselis hydrochloride

    		Bacterial Antibiotic Infection
    Cefoselis hydrochloride, the fourth gen-eration of cephalosporin, is a β-lactam antibiotic. Cefoselis hydrochloride exhibits good activity against a wide range of Gram-positive and Gram-negative organisms. Cefoselis hydrochloride penetrates the blood-brain barrier .
    Cefoselis hydrochloride
  • HY-B0186BR
    Cefoselis sulfate (Standard)

    FK-037 (Standard)

    		 Reference Standards Bacterial Antibiotic Infection
    Cefoselis (sulfate) (Standard) is the analytical standard of Cefoselis (sulfate). This product is intended for research and analytical applications. Cefoselis sulfate (FK-037), the fourth gen-eration of cephalosporin, is a β-lactam antibiotic. Cefoselis sulfate exhibits good activity against a wide range of Gram-positive and Gram-negative organisms. Cefoselis sulfate penetrates the blood-brain barrier[1][2][3].
    Cefoselis sulfate (Standard)
  • HY-107330R
    (6R,7S)-Cefminox sodium heptahydrate (Standard)

    		Reference Standards Antibiotic Others
    (6R,7S)-Cefminox (sodium heptahydrate) (Standard) is the analytical standard of (6R,7S)-Cefminox (sodium heptahydrate). This product is intended for research and analytical applications. (6R,7S)-Cefminox sodium heptahydrate is an isomer of Cefminox sodium heptahydrate. Cefminox sodium heptahydrate is a β-lactam cephalosporin antibiotic, which exhibits a broad spectrum of antibacterial activity[1].
    (6R,7S)-Cefminox sodium heptahydrate (Standard)
  • HY-B0712AR
    Ceftriaxone sodium hydrate (Standard)

    Ro 13-9904 sodium hydrate (Standard)

    		 Reference Standards Bacterial Antibiotic GSK-3 Aurora Kinase Infection Cancer
    Ceftriaxone (sodium hydrate) (Standard) is the analytical standard of Ceftriaxone (sodium hydrate). This product is intended for research and analytical applications. Ceftriaxone sodium hydrate (Ro 13-9904 sodium hydrate) is a broad spectrum β-lactam third-generation cephalosporin antibiotic, which has good antibacterial activity against a variety of gram-negative and positive bacteria. Ceftriaxone sodium hydrate is a covalent inhibitor of GSK3β with IC50 value of 0.78 μM. Ceftriaxone sodium hydrate is an inhibitor of Aurora B. Ceftriaxone sodium hydrate has anti-inflammatory, antitumor and antioxidant activities. Ceftriaxone sodium hydrate can be used in the study of bacterial infections and meningitis .
    Ceftriaxone sodium hydrate (Standard)
  • HY-B1275AR
    Cephalothin (Standard)

    Cephalotin (Standard)

    		 Beta-lactamase Reference Standards Bacterial Antibiotic Cardiovascular Disease Infection
    Cephalothin (Cephalotin) (Standard) is the analytical standard of Cephalothin (HY-B1275A). This product is intended for research and analytical applications. Cephalothin is a semi-synthetic cephalosporin antibiotic and beta-lactam antibiotic. Cephalothin inhibits class C β-lactamase AmpC, with an Ki of 0.32 µM. Cephalothin binds to penicillin-binding proteins, interfering with the cross-linking of peptidoglycan in the cell wall and thus hindering the normal synthesis of the bacterial cell wall. Cephalothin shows antibacterial activity against a variety of bacteria. Cephalothin can be used in hematological and nephrotoxicity studies .
    Cephalothin (Standard)
  • HY-B1275R
    Cephalothin sodium (Standard)

    Cefalotin sodium (Standard)

    		 Reference Standards Bacterial Antibiotic Cardiovascular Disease Infection
    Cephalothin (Cephalotin) sodium (Standard) is the analytical standard of Cephalothin sodium (HY-B1275). This product is intended for research and analytical applications. Cephalothin sodium is a semi-synthetic cephalosporin antibiotic and beta-lactam antibiotic. Cephalothin inhibits class C β-lactamase AmpC, with an Ki of 0.32 µM. Cephalothin sodium binds to penicillin-binding proteins, interfering with the cross-linking of peptidoglycan in the cell wall and thus hindering the normal synthesis of the bacterial cell wall. Cephalothin sodium shows antibacterial activity against a variety of bacteria. Cephalothin sodium can be used in hematological and nephrotoxicity studies .
    Cephalothin sodium (Standard)
  • HY-177949
    ETX1317

    		Beta-lactamase Bacterial Infection
    ETX1317 is a β-lactamase inhibitor that restores the antibacterial activity of several classes of β-lactam antibiotics, including third-generation cephalosporins such as Cefpodoxime (HY-A0251). ETX1317 can be used for research on bacterial infection .
    ETX1317
  • HY-W747255
    Cephalexin sodium

    		Antibiotic Infection Metabolic Disease
    Cephalexin sodium is an orally active cephalosporin Antibiotic. Cephalexin sodium disrupts bacterial cell wall synthesis and inhibits the growth of susceptible Gram-positive bacteria and some Gram-negative bacteria. Cephalexin sodium induces acute renal failure when overdosed in laboratory animals. Cephalexin sodium can be used in studies related to bacterial infections .
    Cephalexin sodium

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