2. Anti-infection
  3. Bacterial Antibiotic
  4. Ceftriaxone sodium salt

Ceftriaxone sodium salt  (Synonyms: Disodium ceftriaxone)

Cat. No.: HY-B0712B Purity: 98.03%
COA Handling Instructions

Ceftriaxone sodium salt (Disodium ceftriaxone) is a third-generation cephalosporin antibiotic with excellent activity against many gram-negative, and reasonable activity against most gram-positive microorganisms. Anti-inflammatory and antioxidant characteristics.

For research use only. We do not sell to patients.

Ceftriaxone sodium salt Chemical Structure

Ceftriaxone sodium salt Chemical Structure

CAS No. : 74578-69-1

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Based on 3 publication(s) in Google Scholar

Other Forms of Ceftriaxone sodium salt:

Ceftriaxone sodium salt Related Antibodies

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Aminoglycoside Glycopeptide Lipopeptide Macrolide Oxazolidinone Quinolone Tetracycline β-lactam

  • Biological Activity

  • Purity & Documentation

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  • Customer Review

Description

Ceftriaxone sodium salt (Disodium ceftriaxone) is a third-generation cephalosporin antibiotic with excellent activity against many gram-negative, and reasonable activity against most gram-positive microorganisms. Anti-inflammatory and antioxidant characteristics[1][2].

IC50 & Target

β-lactam

 

Clinical Trial
Molecular Weight

598.54

Appearance

Solid

Formula

C18H16N8Na2O7S3
CAS No.
SMILES

O=C(O[Na])C(N12)=C(CSC(N(C)N=C3O[Na])=NC3=O)CS[C@]2([H])[C@H](NC(/C(C4=CSC(N)=N4)=N\OC)=O)C1=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 1 years; -20°C, 6 months (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (83.54 mM; Need ultrasonic)

H2O : ≥ 40 mg/mL (66.83 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.6707 mL 8.3537 mL 16.7073 mL
5 mM 0.3341 mL 1.6707 mL 3.3415 mL
10 mM 0.1671 mL 0.8354 mL 1.6707 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  PBS

    Solubility: 100 mg/mL (167.07 mM); Clear solution; Need ultrasonic

  • 2.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% Saline

    Solubility: ≥ 2.5 mg/mL (4.18 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in Saline)

    Solubility: ≥ 2.5 mg/mL (4.18 mM); Clear solution

*All of the co-solvents are available by MedChemExpress (MCE).
Purity & Documentation
References
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Ceftriaxone sodium salt Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Ceftriaxone74578-69-1Disodium ceftriaxoneBacterialAntibioticthird-generationcephalosporingram-negativeinflammatoryantioxidanthepatorenaldamagesInhibitorinhibitorinhibit

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