Cefalonium-d4 hydrate
Based on 1 Customer Validation
Cefalonium-d4 hydrate is the deuterated-labeled Cefalonium hydrate (HY-B1252A). Cefalonium hydrate is a first-generation cephalosporin bactericidal antimicrobial agent. Cefalonium hydrate can be used in studies related to bovine mastitis, Staphylococcus aureus-induced mastitis and intramammary infections.
For research use only. We do not sell to patients.
- Formula: C20H18D4N4O5S2.xH2O
- Molecular Weight:458.51 (free base)
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Antibiotic Isoforms
More
Biological Activity
Description
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
-
Unlabeled CAS 1486466-27-6
-
Molecular Weight 458.51 (free base)
-
Formula C20H18D4N4O5S2.xH2O
-
SMILES
[2H]C1=C([2H])[N+](CC2=C(N3[C@](SC2)([C@@H](C3=O)NC(CC4=CC=CS4)=O)[H])C([O-])=O)=C([2H])C([2H])=C1C(N)=O.O.[x]
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Harada K, et al. Assessment of the Usefulness of Cefapirin and Cefalonium Disks for Susceptibility Testing of Staphylococcus aureus Isolates from Bovine Mastitis. Antibiotics (Basel). 2020 Apr 21;9(4):197. [Content Brief]
[2]. Demon D, et al. The intramammary efficacy of first generation cephalosporins against Staphylococcus aureus mastitis in mice. Veterinary microbiology. 2012 Nov 09;160(1-2):141-50. [Content Brief]
[3]. Berry EA, et al. Effect of an intramammary teat seal and dry cow antibiotic in relation to dry period length on postpartum mastitis. Journal of dairy science. 2007 Feb;90(2):760-5. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)