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enantioselective

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (4) Amino Acid Derivatives (2) Antibiotic (1) Autophagy (2) Bacterial (1) Biochemical Assay Reagents (6) Cholinesterase (ChE) (1) Dopamine Receptor (2) Drug Intermediate (2) Drug Isomer (1) Drug Metabolite (1) Endogenous Metabolite (3) FGFR (1) FLAP (1) Leukotriene Receptor (1) Parasite (2) Potassium Channel (2) Reference Standards (1) SARS-CoV (2) Toll-like Receptor (TLR) (2)
By Research Areas:	Cancer (3) Cardiovascular Disease (1) Infection (3) Inflammation/Immunology (1) Metabolic Disease (2) Neurological Disease (7)

Inhibitors & Agonists

Fluorescent Dyes

Biochemical Assay Reagents

Peptides

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-19545A

SCH-23390 hydrochloride Maximum Cited Publications 31 Publications Verification R-(+)-SCH-23390 hydrochloride	Dopamine Receptor 5-HT Receptor Potassium Channel	Neurological Disease
SCH-23390 hydrochloride (R-(+)-SCH-23390 hydrochloride) is a potent and selective dopamine D₁-like receptor antagonist with K_is of 0.2 nM and 0.3 nM for the D₁ and D₅ receptor, respectively. SCH-23390 hydrochloride is a potent and high efficacy human 5-HT_2C receptor agonist with a K_i of 9.3 nM. SCH-23390 hydrochloride also binds with high affinity to the 5-HT₂ and 5-HT_1C receptors. SCH-23390 hydrochloride inhibits G protein-coupled inwardly rectifying potassium (GIRK) channels with an IC₅₀ of 268 nM .

HY-41121

Boc-L-Ala-OH 1 Publications Verification Boc-Ala-OH	Amino Acid Derivatives	Cancer
Boc-L-Ala-OH (Boc-Ala-OH) is a single N-protected amino acid ligand and a protected L-alanine derivative. Boc-L-Ala-OH promotes Pd (II)-catalyzed enantioselective C-H alkenylation and kinetic resolution. Boc-L-Ala-OH serves as a coupling reagent for the synthesis of liver-targeted glycogen phosphorylase inhibitors and P6A metabolites, and also acts as a negative control in synthesis studies of betulinic acid amino acid esters. Boc-L-Ala-OH is applicable to research on epidermoid squamous cell carcinoma .

HY-75070

(+)-1-(1-Naphthyl)ethylamine	Biochemical Assay Reagents	Others
(+)-1-(1-Naphthyl)ethylamine ((+)-1-(1-NEA)) is a chiral modifier used to introduce enantioselectivity in catalytic hydrogenation reactions. 1-NEA can undergo H-D exchange with D2 in solution to form N?D bonds. That is, 1-NEA can complete Pt surface adsorption and protonation through amine N atoms, indicating that NEA molecules have the potential to impart enantioselectivity to Pt hydrogenation catalysts .

HY-W007337

3-Bromopropan-1-ol	Endogenous Metabolite	Metabolic Disease
3-Bromopropan-1-ol is an endogenous metabolite. 3-Bromopropan-1-ol is significantly up-regulated during the estrous period of buffaloes. 3-Bromopropan-1-ol acts as an alkylating agent . 3-Bromopropan-1-ol participates in the enantioselective synthesis of nornicotine enantiomers. 3-Bromopropan-1-ol can be used in studies related to estrus detection in buffaloes .

HY-B1370B

(R)-Hydroxychloroquine (R)-HCQ	Parasite Toll-like Receptor (TLR) SARS-CoV Autophagy	Infection
(R)-Hydroxychloroquine is the enantiomer of Hydroxychloroquine . Hydroxychloroquine is a synthetic antimalarial agent which can also inhibit Toll-like receptor 7/9 (TLR7/9) signaling. Hydroxychloroquine is efficiently inhibits SARS-CoV-2 infection in vitro .

HY-B1370A

(S)-Hydroxychloroquine (S)-HCQ	Parasite Toll-like Receptor (TLR) SARS-CoV Autophagy	Infection
(S)-Hydroxychloroquine ((S)-HCQ) is the enantiomer of Hydroxychloroquine . Hydroxychloroquine, a synthetic antimalarial agent, inhibits Toll-like receptor 7/9 (TLR7/9) signaling, and shows efficiently inhibits SARS-CoV-2 infection in vitro .

HY-Y1778

N-(Diphenylmethylene)glycine tert-butyl ester	Drug Intermediate	Others
N-(Diphenylmethylene)glycine tert-butyl ester is a protected glycine derivative. N-(Diphenylmethylene)glycine tert-butyl ester undergoes enantioselective alkylation to produce α-alkyl-α-amino acid derivatives .

HY-Y1416

3-(1-Cyanoethyl)benzoic acid DF2107Y	Biochemical Assay Reagents	Others
3-(1-Cyanoethyl)benzoic acid (DF2107Y) is a benzoic acid that can be used to screen cobalt containing nitrile hydratases (NHases) .

HY-108400

SCH-23390 maleate R-(+)-SCH-23390 maleate	Dopamine Receptor 5-HT Receptor Potassium Channel	Neurological Disease
SCH-23390 maleate (R-(+)-SCH-23390 maleate) is a potent and selective dopamine D₁-like receptor antagonist with K_is of 0.2 nM and 0.3 nM for the D₁ and D₅ receptor, respectively. SCH-23390 maleate is a potent and high efficacy human 5-HT_2C receptor agonist with a K_i of 9.3 nM. SCH-23390 maleate also binds with high affinity to the 5-HT₂ and 5-HT_1C receptors. SCH-23390 maleate inhibits G protein-coupled inwardly rectifying potassium (GIRK) channels with an IC₅₀ of 268 nM .

HY-136824

Napyradiomycin A1	Bacterial Antibiotic	Infection Cancer
Napyradiomycin A1 is one enantioselective compound of napyradiomycins. napyradiomycins are an intriguing family of halogenated natural products with activity against several tumor cell lines as well as some bacterial strains .

HY-Y1662

D-Aminoacylase E.C. 3.5.1.81; D-Amino acid acylase; N-Acyl-D-amino-acid deacylase	Biochemical Assay Reagents	Others
D-Aminoacylase (E.C. 3.5.1.81) catalyzes the enantioselective hydrolysis of Nacyl-D-amino acids to produce D -amino acids .

HY-W010685

[1,4-BIs(diphenylphosphino)butane](1,5-cyclooctadiene)rhodium(I) tetrafluoroborate [Rh(dppb)(COD)]BF4	Biochemical Assay Reagents Endogenous Metabolite	Others
[1,4-Bis(diphenylphosphino)butane](1,5-cyclooctadiene)rhodium(I) tetrafluoroborate ([Rh(dppb)(COD)]BF4) serves as a rhodium-based catalyst that facilitates regioselective hydrogenation and enantioselective reductive amination reactions.

HY-167663

Ebalzotan	5-HT Receptor	Neurological Disease
Ebalzotan is a 5-HT1A receptor agonist with activity in the study of depression. Ebalzotan can serve as a precursor to important active pharmaceutical ingredients. The synthesis of Ebalzotan involves a multi-enzyme catalyzed reduction reaction to obtain saturated primary or secondary alcohols in high yields and high enantioselectivity .

HY-167663A

(S)-Ebalzotan	5-HT Receptor	Neurological Disease
(S)-Ebalzotan is the S-form of Ebalzotan (HY-167663). Ebalzotan is a 5-HT1A receptor agonist with activity in the study of depression. Ebalzotan can serve as a precursor to important active pharmaceutical ingredients. The synthesis of Ebalzotan involves a multi-enzyme catalyzed reduction reaction to obtain saturated primary or secondary alcohols in high yields and high enantioselectivity .

HY-14165A

(S)-Veliflapon (S)-BAY X 1005; (S)-DG-031	Leukotriene Receptor FLAP	Inflammation/Immunology
(S)-Veliflapon ((S)-BAY X 1005) is an orally active inhibitor of leukotriene biosynthesis and 5-lipoxygenase activating protein (FLAP). (S)-Veliflapon inhibits the formation of leukotriene B4 (LTB4) in rat, mouse and human leukocytes with IC₅₀ values of 0.026 µM, 0.039 µM and 0.22 µM respectively. (S)-Veliflapon showes enantioselectivity in human whole blood .

HY-101544

ARQ 069	FGFR	Cancer
ARQ 069, an analog of ARQ 523, inhibits FGFR in an enantiospecific manner. ARQ 069 targets the unphosphorylated, inactive forms of FGFR1/FGFR2 kinases (IC₅₀s of 0.84 μM and 1.23 μM, respectively). ARQ 069 inhibits FGFR1/FGFR2 autophosphorylation (IC₅₀s of 2.8 and 1.9 μM, respectively) through a mechanism in a non-ATP competitive dependent manner .

HY-W129533

tert-Butyl 1H-indol-4-ylcarbamate	Biochemical Assay Reagents	Others
tert-Butyl 1H-indol-4-ylcarbamate is a nucleophilic reagent. tert-Butyl 1H-indol-4-ylcarbamate induces the formation of the stable triple hydrogen-bonded complex A-TS-Re. tert-Butyl 1H-indol-4-ylcarbamate undergoes Friedel-Crafts reactions with β,γ-unsaturated α-ketiminoesters .

HY-124886

N-(Phenylacetyl)-L-phenylalanine N-Phenylacetylphenylalanine	Amino Acid Derivatives	Others
N-(Phenylacetyl)-L-phenylalanine (N-Phenylacetylphenylalanine) is an amino acid analog. N-(Phenylacetyl)-L-phenylalanine is produced via the enantioselective acylation of L-phenylalanine catalyzed by penicillin G acylase from Alcaligenes faecalis. N-(Phenylacetyl)-L-phenylalanine undergoes hydrolysis in aqueous media .

HY-119399

Salithion Dioxabenzofos	Cholinesterase (ChE)	Neurological Disease
Salithion is an acetylcholinesterase inhibitor and neurotoxicant. Salithion binds to the active site of acetylcholinesterase to interfere with acetylcholine hydrolysis, and there is an enantioselective difference between its (R) and (S) enantiomers .

HY-Y1416R

3-(1-Cyanoethyl)benzoic acid (Standard) DF2107Y (Standard)	Biochemical Assay Reagents Reference Standards	Others
3-(1-Cyanoethyl)benzoic acid (Standard) is the analytical standard of 3-(1-Cyanoethyl)benzoic acid. This product is intended for research and analytical applications. 3-(1-Cyanoethyl)benzoic acid (DF2107Y) is a benzoic acid that can be used to screen cobalt containing nitrile hydratases (NHases) .

HY-113724

S-8666	Endogenous Metabolite	Cardiovascular Disease Metabolic Disease
S-8666 is an orally active uricosuric antihypertensive diuretic. The S-8666 has both S-(-)- and R-(+)-isomers. The diuretic and sodium-excretion activities of it are entirely dominated by the S-(-)-isomer, while the R-(+)-isomer shows no significant activity. S-8666 relies on the organic acid transport system to be secreted through the proximal tubule. S-8666 exhibits a clear uric acid excretion-promoting activity and diuretic effect in various species (such as rats and chimpanzees) .

HY-W725194

4-Fluoro deschloroketamine hydrochloride 4-FDCK hydrochloride	Drug Isomer	Neurological Disease
4-Fluoro deschloroketamine (4-FDCK) hydrochloride (Page 145) is an amine cyclohexane compound, with its (R)-configuration being Blixeprodil (HY-172419) (an NMDA receptor antagonist). 4-Fluoro deschloroketamine hydrochloride can be used for the study of depression .

HY-12386A

(S)-4-(3-Thienyl)phenyl-α-methylacetic acid	Drug Intermediate	Others
(S)-4-(3-Thienyl) phenyl-α-methylacetic acid is the S-enantiomer of the racemate corresponding to 4-(3-Thienyl) phenyl-α-methylacetic acid. As a key synthetic precursor, 4-(3-Thienyl) phenyl-α-methylacetic acid is used to prepare the cyclooxygenase inhibitor S-Atliprofen .

HY-116627

(R)-6-Hydroxybuspirone BMS-442608	Drug Metabolite	Neurological Disease
(R)-6-Hydroxybuspirone is a metabolite of the anxiolytic agent Buspirone (HY-B1115A). (R)-6-Hydroxybuspirone itself also has anxiolytic activity .

N-(Diphenylmethylene)glycine tert-butyl ester	Fluorescent Dyes
N-(Diphenylmethylene)glycine tert-butyl ester is a protected glycine derivative. N-(Diphenylmethylene)glycine tert-butyl ester undergoes enantioselective alkylation to produce α-alkyl-α-amino acid derivatives .

Cat. No.	Product Name	Type

HY-75070

(+)-1-(1-Naphthyl)ethylamine	Biochemical Assay Reagents
(+)-1-(1-Naphthyl)ethylamine ((+)-1-(1-NEA)) is a chiral modifier used to introduce enantioselectivity in catalytic hydrogenation reactions. 1-NEA can undergo H-D exchange with D2 in solution to form N?D bonds. That is, 1-NEA can complete Pt surface adsorption and protonation through amine N atoms, indicating that NEA molecules have the potential to impart enantioselectivity to Pt hydrogenation catalysts .

(+)-1-(1-Naphthyl)ethylamine

Biochemical Assay Reagents

(+)-1-(1-Naphthyl)ethylamine ((+)-1-(1-NEA)) is a chiral modifier used to introduce enantioselectivity in catalytic hydrogenation reactions. 1-NEA can undergo H-D exchange with D2 in solution to form N?D bonds. That is, 1-NEA can complete Pt surface adsorption and protonation through amine N atoms, indicating that NEA molecules have the potential to impart enantioselectivity to Pt hydrogenation catalysts .

HY-W007337

3-Bromopropan-1-ol	Biochemical Assay Reagents
3-Bromopropan-1-ol is an endogenous metabolite. 3-Bromopropan-1-ol is significantly up-regulated during the estrous period of buffaloes. 3-Bromopropan-1-ol acts as an alkylating agent . 3-Bromopropan-1-ol participates in the enantioselective synthesis of nornicotine enantiomers. 3-Bromopropan-1-ol can be used in studies related to estrus detection in buffaloes .

Cat. No.	Product Name	Target	Research Area

HY-41121

Boc-L-Ala-OH 1 Publications Verification Boc-Ala-OH	Amino Acid Derivatives	Cancer
Boc-L-Ala-OH (Boc-Ala-OH) is a single N-protected amino acid ligand and a protected L-alanine derivative. Boc-L-Ala-OH promotes Pd (II)-catalyzed enantioselective C-H alkenylation and kinetic resolution. Boc-L-Ala-OH serves as a coupling reagent for the synthesis of liver-targeted glycogen phosphorylase inhibitors and P6A metabolites, and also acts as a negative control in synthesis studies of betulinic acid amino acid esters. Boc-L-Ala-OH is applicable to research on epidermoid squamous cell carcinoma .

Napyradiomycin A1	Infection Quinones Microorganisms Classification of Application Fields Naphthalene Quinones Disease Research Fields Cancer Source Classification	Bacterial Antibiotic
Napyradiomycin A1 is one enantioselective compound of napyradiomycins. napyradiomycins are an intriguing family of halogenated natural products with activity against several tumor cell lines as well as some bacterial strains .

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enantioselective

Inhibitors & Agonists

Fluorescent Dyes

Biochemical Assay Reagents

Peptides

NaturalProducts

Natural
Products