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Cat. No.: HY-136824

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Napyradiomycin A1

Napyradiomycin A1 is one enantioselective compound of napyradiomycins. napyradiomycins are an intriguing family of halogenated natural products with activity against several tumor cell lines as well as some bacterial strains.

For research use only. We do not sell to patients.

CAS No.: 103106-24-7
Formula: C₂₅H₃₀Cl₂O₅
Molecular Weight:481.41

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

Napyradiomycin A1 Chemical Structure

CAS No.: 103106-24-7

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

All Antibiotic Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
HUVEC	GI₅₀	27.6 μM Compound: 1	Antiproliferative activity against HUVEC after 72 hrs by Celltiter-Glo luminescent cell viability assay Antiproliferative activity against HUVEC after 72 hrs by Celltiter-Glo luminescent cell viability assay	[PMID: 28749137]
HUVEC	IC₅₀	10 μM Compound: 1	Antiangiogenic activity in HUVEC assessed as inhibition of VEGF-induced tube formation after 24 hrs by calcein-AM dye based fluorescence assay Antiangiogenic activity in HUVEC assessed as inhibition of VEGF-induced tube formation after 24 hrs by calcein-AM dye based fluorescence assay	[PMID: 28749137]

Chemical Information

CAS No. 103106-24-7
Molecular Weight 481.41
Formula C₂₅H₃₀Cl₂O₅
SMILES

C/C(CC/C=C(C)/C)=C\C[C@@](C(C1=CC(O)=CC(O)=C21)=O)(OC3(C)C)[C@@](C2=O)(C[C@H]3Cl)Cl
Structure Classification
- Quinones
- Naphthalene Quinones
Initial Source
- Microorganisms
Chainia rubra
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Scott A Snyder, et al. Enantioselective total synthesis of (-)-napyradiomycin A1 via asymmetric chlorination of an isolated olefin. J Am Chem Soc. 2009 Apr 29;131(16):5744-5. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
- Description
Chemical Information
Purity & Documentation
References

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Napyradiomycin A1

Norgestrel-d6

Hydrocortisone-d4

Retinoic acid

Gingerenone A

Levonorgestrel

Estradiol-d2

Retinoic acid (Standard)

Retinoic acid (GMP)

Levonorgestrel (Standard)

Malformin A1

3-Keto fusidic acid

Dienogest-d8

All Antibiotic Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Napyradiomycin A1

Norgestrel-d6

Hydrocortisone-d4

Retinoic acid

Gingerenone A

Levonorgestrel

Estradiol-d2

Retinoic acid (Standard)

Retinoic acid (GMP)

Levonorgestrel (Standard)

Malformin A1

3-Keto fusidic acid

Dienogest-d8

All Antibiotic Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Napyradiomycin A1 Related Classifications

HY-136824 Related Classifications