glutamyl+transferase

By Targets:	γ-Glutamyl Transferase (GGT) (4) Amino Acid Derivatives (1) Antibiotic (1) Apoptosis (1) ASCT (1) Biochemical Assay Reagents (2) Endogenous Metabolite (3) Fungal (3) Glutathione S-transferase (1) Leukotriene Receptor (1) Phosphatase (1)
By Research Areas:	Cancer (3) Cardiovascular Disease (1) Infection (4) Inflammation/Immunology (2) Metabolic Disease (3) Neurological Disease (1)

Targets Recommended: γ-Glutamyl Transferase (GGT)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-E70452

Microbial Transglutaminase MTG; MTGase; Protein-glutamine-γ-glutamyltransferase	Biochemical Assay Reagents	Others
Microbial Transglutaminase (MTG) is a transglutaminase. Enzymes have high catalytic efficiency, high specificity, and mild operating conditions. It can be applied in industries such as pharmaceuticals, industrial production, food manufacturing, and aquaculture .

HY-W011391

GPNA hydrochloride Maximum Cited Publications 7 Publications Verification	Apoptosis ASCT	Cancer
GPNA hydrochloride is a well known substrate of the enzyme γ-glutamyltransferase (GGT). GPNA hydrochloride is a specific glutamine (Gln) transporter ASCT2 inhibitor. GPNA hydrochloride also inhibit Na ⁺-dependent carriers, such as SNAT family (SNAT1/2/4/5), and the Na ⁺-independent leucine transporters LAT1/2. GPNA reversibly induces apoptosis in A549 cells .

HY-15936

L-Glutamic acid γ-(3-carboxy-4-nitroanilide) ammonium salt L-γ-Glutamyl-3-carboxy-4-nitroanilide ammonium salt	γ-Glutamyl Transferase (GGT)	Metabolic Disease
L-Glutamic acid γ-(3-carboxy-4-nitroanilide) ammonium salt is a donor substrate of *gamma-glutamyltransferase* (GGT)** that can be used to measure GGT activity .

HY-P2997

*γ-glutamyltransferase, Porcine kidney* 1 Publications Verification GGT, Porcine kidney	Endogenous Metabolite	Cancer
γ-glutamyltransferase, Porcine kidney (GGT, Porcine kidney) is an enzyme located on the outer surface of the cell membrane. γ-glutamyltransferase, Porcine kidney maintains the physiological concentration of cytoplasmic glutathione and the cell's defense against oxidative stress by cleaving extracellular glutathione and increasing the availability of amino acids. γ-glutamyltransferase, Porcine kidney is used for pancreatic cancer research .

HY-125539

Roridin E	Antibiotic Phosphatase Fungal	Infection
Roridin E is a glucose-6-phosphatase (G6Pase) inhibitor and antibiotic, and is a metabolic byproduct of Roridin A (HY-N9599). Roridin E induces significant oxidative stress, characterized by depletion of glutathione in vivo, induction of hepatic lipid peroxidation, and inhibition of renal superoxide dismutase activity. Roridin E reduces blood glucose levels in rats, but exhibits acute toxicity (which is enhanced when co-administered with linoleic acid (HY-N0729)) and causes hepatotoxicity in male albino mice. Roridin E induces a decrease in total blood protein and increases in the levels of total lipids, γ-glutamyltransferase, alkaline phosphatase, and 5'-nucleotidase. Roridin E can be isolated from molds, and possesses cytostatic and antifungal activities similar to those of Verrucarin A (HY-107426) and Roridin A. Roridin E exhibits in vivo activity in rodents and is commonly used in hepatotoxicity-related studies .

HY-130440

Leukotriene F4	Endogenous Metabolite Leukotriene Receptor	Inflammation/Immunology
Leukotriene F4 (LTF4), is a lipid that belongs to the Cysteinyl Leukotriene (CysTL) family . Leukotriene F4 induces bronchoconstriction with an ED₅₀ of 16 μg/kg . The precursor of LTF4 is Leukotriene E4 (LTE4), which isformed from the action of a glutamyl transferase .

HY-154996

*Gamma-Glutamyl Transferase-IN-2*	Fungal γ-Glutamyl Transferase (GGT)	Infection
Gamma-Glutamyl Transferase-IN-2 (compound 4dq) is a β-carboline 1-hydrazide inhibitor with antifungal and antibacterial activities, targeting to *glutamyltransferase. Gamma-Glutamyl* Transferase-IN-2 acts function by resulting the accumulation of reactive oxygen species, destruction of cell membranes, and dysregulation of histone acetylation .

HY-154993

*Gamma-Glutamyl Transferase-IN-1*	Fungal γ-Glutamyl Transferase (GGT)	Infection
Gamma-Glutamyl Transferase-IN-1 (compound 4de) is a β-carboline 1-hydrazide inhibitor with antifungal and antibacterial activities, targeting to *glutamyltransferase. Gamma-Glutamyl* Transferase-IN-1 acts function by resulting the accumulation of reactive oxygen species, destruction of cell membranes, and dysregulation of histone acetylation .

HY-E70996

*Gamma-Glutamyl Transferase, Human*	Endogenous Metabolite	Metabolic Disease
Gamma-Glutamyl Transferase, Human (EC 2.3.2.2) is an enzyme capable of transferring the γ-glutamyl functional group. Gamma-Glutamyl Transferase, Human (EC 2.3.2.2) catalyzes the transfer of the γ-glutamyl group of glutathione to a receptor, which can be an amino acid, peptide, or water (to produce glutamate).

HY-W142025

6-Diazo-5-oxo-D-norleucine	Amino Acid Derivatives γ-Glutamyl Transferase (GGT)	Metabolic Disease
6-Diazo-5-oxo-D-norleucine, a D-Glutamine (HY-100587) analog, is a γ-glutamyl transferase inhibitor .

HY-121624

Anthglutin	Glutathione S-transferase	Infection
Anthglutin is a gamma-glutamyltransferase inhibitor isolated from Penicillium oxalicum cultures. The Ki values of Anthglutin for different enzymes are: porcine kidney enzyme 5.7 μM, human kidney enzyme 18.3 μM, human liver soluble enzyme 13.6 μM, and conjugated enzyme 10.2 μM. Anthglutin had no significant effect on intestinal absorption of methionine in rats .

HY-P2997B

*γ-glutamyltransferase, Human (HEK293)*	Biochemical Assay Reagents	Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
γ-glutamyltransferase, Human (HEK293) is a γ-glutamyltransferase expressed in HEK293 cells. γ-glutamyltransferase participates in glutathione metabolism. Serum γ-glutamyltransferase activity is identified as a predictor of atherosclerotic complications, and has prognostic value for cardiovascular diseases and stroke. γ-glutamyltransferase also serves as a biomarker for carcinogenesis and tumor progression .

Cat. No.	Product Name	Type

HY-15936

L-Glutamic acid γ-(3-carboxy-4-nitroanilide) ammonium salt L-γ-Glutamyl-3-carboxy-4-nitroanilide ammonium salt	Biochemical Assay Reagents
L-Glutamic acid γ-(3-carboxy-4-nitroanilide) ammonium salt is a donor substrate of *gamma-glutamyltransferase* (GGT)** that can be used to measure GGT activity .

Cat. No.	Product Name	Target	Research Area

HY-W142025

6-Diazo-5-oxo-D-norleucine	Amino Acid Derivatives γ-Glutamyl Transferase (GGT)	Metabolic Disease
6-Diazo-5-oxo-D-norleucine, a D-Glutamine (HY-100587) analog, is a γ-glutamyl transferase inhibitor .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-125539

Roridin E	Structural Classification Natural Products Microorganisms Source Classification	Antibiotic Phosphatase Fungal
Roridin E is a glucose-6-phosphatase (G6Pase) inhibitor and antibiotic, and is a metabolic byproduct of Roridin A (HY-N9599). Roridin E induces significant oxidative stress, characterized by depletion of glutathione in vivo, induction of hepatic lipid peroxidation, and inhibition of renal superoxide dismutase activity. Roridin E reduces blood glucose levels in rats, but exhibits acute toxicity (which is enhanced when co-administered with linoleic acid (HY-N0729)) and causes hepatotoxicity in male albino mice. Roridin E induces a decrease in total blood protein and increases in the levels of total lipids, γ-glutamyltransferase, alkaline phosphatase, and 5'-nucleotidase. Roridin E can be isolated from molds, and possesses cytostatic and antifungal activities similar to those of Verrucarin A (HY-107426) and Roridin A. Roridin E exhibits in vivo activity in rodents and is commonly used in hepatotoxicity-related studies .

HY-130440

Leukotriene F4	Classification of Application Fields Ketones, Aldehydes, Acids Endogenous metabolite Inflammation/Immunology Disease Research Fields Source Classification	Endogenous Metabolite Leukotriene Receptor
Leukotriene F4 (LTF4), is a lipid that belongs to the Cysteinyl Leukotriene (CysTL) family . Leukotriene F4 induces bronchoconstriction with an ED₅₀ of 16 μg/kg . The precursor of LTF4 is Leukotriene E4 (LTE4), which isformed from the action of a glutamyl transferase .

HY-121624

Anthglutin	Microorganisms Ketones, Aldehydes, Acids Source Classification	Glutathione S-transferase
Anthglutin is a gamma-glutamyltransferase inhibitor isolated from Penicillium oxalicum cultures. The Ki values of Anthglutin for different enzymes are: porcine kidney enzyme 5.7 μM, human kidney enzyme 18.3 μM, human liver soluble enzyme 13.6 μM, and conjugated enzyme 10.2 μM. Anthglutin had no significant effect on intestinal absorption of methionine in rats .

Species:	Human (4) Mouse (1)
Tag:	His (5)
Source:	HEK293 (3) Sf9 insect cells (2)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P76114Y

	TGM2/Transglutaminase 2 Protein, Human (sf9, His, solution) Protein-glutamine gamma-glutamyltransferase 2; Transglutaminase C; TGase-2	Human	Sf9 insect cells
	In summary, TGM2 is a multifunctional enzyme that plays crucial roles in various cellular processes. It acts as a protein-glutamine gamma-glutamyl transferase, mediating the cross-linking of proteins involved in cellular functions. TGM2/Transglutaminase 2 Protein, Human (sf9, His, solution) is the recombinant human-derived TGM2/Transglutaminase 2, expressed by Sf9 insect cells, with N-His labeled tag.

HY-P71132A

	TGM2/Transglutaminase 2 Protein, Mouse (HEK293, C-His) Protein-glutamine gamma-glutamyltransferase 2; Tgm2; Tissue transglutaminase; Transglutaminase C; TGase-2	Mouse	HEK293
	The TGM2/transglutaminase 2 protein is a calcium-dependent acyltransferase involved in bone development, angiogenesis, wound healing, and apoptosis.TGM2 is also involved in neurotransmission-independent actions and serves as a signal transducer in α-1 adrenergic receptor-mediated pathways.TGM2/Transglutaminase 2 Protein, Mouse (HEK293, C-His) is the recombinant mouse-derived TGM2/Transglutaminase 2 protein, expressed by HEK293 , with C-10*His labeled tag.

HY-P700729

	GGT1 Protein, Human (HEK293, His) Gamma-glutamyltransferase 1; GGT 1; CD224; GGT; GGT-1; GGTD; D22S672; D22S73; D22S732	Human	HEK293
	The GGT1 protein cleaves gamma-glutamyl bonds of extracellular glutathione, glutathione conjugates, and other gamma-glutamyl compounds. Its metabolism releases free glutamate and cysteinylglycine, which are hydrolyzed into cysteine and glycine. GGT1 Protein, Human (HEK293, His) is the recombinant human-derived GGT1 protein, expressed by HEK293 , with N-His labeled tag.

HY-P77257

	Transglutaminase 3/TGM3 Protein, Human (sf9, His) Protein-glutamine gamma-glutamyltransferase E; Transglutaminase E; TGase-3	Human	Sf9 insect cells
	Transglutaminase 3 (TGM3) acts as a catalyst in the formation of calcium-dependent isopeptide cross-links between glutamine and lysine residues in a variety of proteins, while mediating the conjugation of polyamines to proteins. Transglutaminase 3/TGM3 Protein, Human (sf9, His) is the recombinant human-derived Transglutaminase 3/TGM3 protein, expressed by Sf9 insect cells , with N-His labeled tag.

HY-P70226

	Coagulation factor XIII A/F13A Protein, Human (HEK293, His) rHuCoagulation factor XIII A chain/F13A, His; Coagulation Factor XIII A Chain; Coagulation Factor XIIIa; Protein-Glutamine Gamma-Glutamyltransferase A Chain; Transglutaminase A Chain; F13A1; F13A	Human	HEK293
	Coagulation factor XIII A chain is the A chain of factor XIII. As a coagulation factor, Factor XIII A chain alters clot stabilization and bleeding. Factor XIII A chain regulates multiple aspects of wound healing: stabilizes fibrin clots and extracellular matrix, modulates monocyte functions, promote angiogenesis, and upregulates proangiogenic early growth response transcription factor 1. Coagulation factor XIII A/F13A Protein, Human (HEK293, His) is the recombinant human-derived Coagulation factor XIII A/F13A protein, expressed by HEK293 , with C-6*His labeled tag.

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Host:	Mouse (2) Rabbit (3)
Reactivity:	Human (5) Rat (4) Mouse (4)
Application:	IHC-P (5) ICC/IF (1) IP (2) WB (4) ELISA (2)
Isotype:	IgG (3) IgG1 (2)
Conjugation:	Non-conjugated (5)
Clonality:	Monoclonal (4) Recombinant (2)
Modification:	Unmodified (4)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P82510

	Transglutaminase 2 Antibody (YA2255) TGM2; Protein-glutamine gamma-glutamyltransferase 2; Tissue transglutaminase; Transglutaminase C; TG(C); TGC; TGase C; Transglutaminase H; TGase H; Transglutaminase-2; TGase-2	WB, IHC-P, IP	Human, Mouse, Rat
	Transglutaminase 2 Antibody (YA2255) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Transglutaminase 2.

HY-P82510A

	Transglutaminase 2 Antibody (YA2255)(PBS only) TGM2; Protein-glutamine gamma-glutamyltransferase 2; Tissue transglutaminase; Transglutaminase C; TG(C); TGC; TGase C; Transglutaminase H; TGase H; Transglutaminase-2; TGase-2	WB, IHC-P, IP	Human, Mouse, Rat
	Transglutaminase 2 Antibody (YA2255) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Transglutaminase 2.

HY-P82889

	GGT1 Antibody (YA2634) GGT1; GGT; Gamma-glutamyltranspeptidase 1; GGT 1; Gamma-glutamyltransferase 1; Glutathione hydrolase 1; Leukotriene-C4 hydrolase; CD224	WB, IHC-P	Human
	GGT1 Antibody (YA2634) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to GGT1.

HY-P86034

	Factor XIIIa Antibody (YA5726) Coagulation factor XIII A chain; Coagulation factor XIIIa; Protein-glutamine gamma-glutamyltransferase A chain; Transglutaminase A chain;	IHC-P, ELISA	Human, Mouse, Rat
	Factor XIIIa Antibody (YA5726) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Factor XIIIa.

HY-P85912

	Factor XIIIa Antibody (YA5604) bA525O21.1; coagulation factor XIII, A1 polypeptide; Coagulation factor XIII A chain; Coagulation factor XIII A1 polypeptide; Coagulation factor XIII A1 subunit; Coagulation factor XIII, A polypeptide; Coagulation factor XIIIa; F13A; F13A_HUMAN; F13a1; Factor XIIIA; Fibrin stabilizing factor, A subunit; Fibrinoligase; FSF, A subunit; Protein glutamine gamma glutamyltransferase A chain; Protein-glutamine gamma-glutamyltransferase A chain; TGase; Transglutaminase A chain; Transglutaminase, plasma; Transglutaminase. plasma	IHC-P, WB, ICC/IF, ELISA	Human, Mouse, Rat
	Factor XIIIa Antibody (YA5604) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Factor XIIIa.

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glutamyl+transferase

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