![2,4-Dichloro-7H-pyrrolo[2,3-d]pyrimidine](https://file.medchemexpress.com/product_pic/hy-40350.gif "Click to View 2,4-Dichloro-7H-pyrrolo[2,3-d]pyrimidine Product Detail")
![2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxaldehyde](https://file.medchemexpress.com/product_pic/hy-42451.gif "Click to View 2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxaldehyde Product Detail")
![2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-methanol](https://file.medchemexpress.com/product_pic/hy-42450.gif "Click to View 2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-methanol Product Detail")
![2,4-Dichlorothieno[3,2-d]pyrimidine](https://file.medchemexpress.com/product_pic/hy-20176.gif "Click to View 2,4-Dichlorothieno[3,2-d]pyrimidine Product Detail")
![7-Chloro-6-fluoro-1-(2-isopropyl-4-methyl-3-pyridyl)pyrido[2,3-d]pyrimidine-2,4-dione](https://file.medchemexpress.com/product_pic/hy-44072.gif "Click to View 7-Chloro-6-fluoro-1-(2-isopropyl-4-methyl-3-pyridyl)pyrido[2,3-d]pyrimidine-2,4-dione Product Detail")
Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
48 Results for "
pyrimidine compound
" in MedChemExpress (MCE) Product Catalog:
Products (48)
48 Results for "pyrimidine compound" in MCE Product Catalog:
4
4 Cited Publications
Synonyms: BIBX 1382
Falnidamol (BIBX 1382) is an orally active, selective EGFR tyrosine kinase inhibitor with an IC50 of 3 nM. Falnidamol displays > 1000-fold lower potency against ErbB2 (IC50=3.4 μM) and a range of other related tyrosine kinases (IC50>10 μM). Falnidamol is a pyrimido-pyrimidine compound and has anti-cancer activity .
3
3 Cited Publications
CGP 57380 is a cell-permeable pyrazolo-pyrimidine compound that acts as a selective inhibitor of Mnk1 with IC50 of 2.2 μM, but has no inhibitory activity against p38, JNK1, ERK1/2, PKC, or Src-like kinases.
1
1 Cited Publications
Synonyms: Acetoacetate methyl ester; Methyl 3-oxobutanoate; Methyl acetoacetate
Target:
Referencia número: HY-171932
No. CAS: 1026029-18-4
Target:
Áreas de investigación:
CaMKIIδ-IN-1 (Compound 15e) is a pyrimidine-based inhibitor of CaMKIIδ with an IC50 of 12 nM .
Target:
Referencia número: HY-W018744
No. CAS: 10132-07-7
Referencia número: HY-40350
No. CAS: 90213-66-4
Áreas de investigación:
DHODH-IN-1 (compound 18d) is a potent Dihydroorotate Dehydrogenase (DHODH) inhibitor with an IC50 of 25 nM. DHODH-IN-1 is an inhibitor of pyrimidine biosynthesis pathway .
Referencia número: HY-W002404
No. CAS: 31462-59-6
Referencia número: HY-W140956
No. CAS: 608-34-4
Target:
Referencia número: HY-42451
No. CAS: 1211443-55-8
Target:
Áreas de investigación:
2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxaldehyde is a drug intermediate for synthesis of various active compounds.
Referencia número: HY-42450
No. CAS: 1374639-77-6
Synonyms: (2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)methanol
Target:
Áreas de investigación:
2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-methanol ((2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)methanol) is a drug intermediate for synthesis of various active compounds.
Referencia número: HY-20176
No. CAS: 16234-14-3
Target:
Áreas de investigación:
2,4-Dichlorothieno[3,2-d]pyrimidine is a thienopyrimidine scaffold and a key synthetic precursor, which is widely used for constructing 4-arylthieno[3,2-d]pyrimidine compounds. 2,4-Dichlorothieno[3,2-d]pyrimidine serves for the development of 4-arylthieno[3,2-d]pyrimidine-based human adenosine A2a receptor antagonists, as well as thienopyrimidine-based PI3K-α inhibitors. In addition, 2,4-Dichlorothieno[3,2-d]pyrimidine has potential application value in studies related to whipworm disease .
Referencia número: HY-149365
No. CAS: 2927557-06-8
Target:
Áreas de investigación:
SIKs-IN-1 (compound 8h), a pyrimidine-5-carboxamide derivative, is a Salt-inducible kinases (SIKs) inhibitor. SIKs regulates the transformation of M1/M2 macrophages, involving in inflammation process. SIKs-IN-1 inhibits SIK activity, up-regulates anti-inflammatory cytokine IL-10, but down-regulates pro-inflammatory cytokine IL-12. SIKs-IN-1 shows excellent anti-inflammatory effects in a DSS-induced colitis model .
Referencia número: HY-44072
No. CAS: 2252403-82-8
Target:
Áreas de investigación:
7-Chloro-6-fluoro-1-(2-isopropyl-4-methyl-3-pyridyl)pyrido[2,3-d]pyrimidine-2,4-dione is a drug intermediate for synthesis of various active compounds.
Referencia número: HY-78337
No. CAS: 34253-03-7
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
