EGFR T790M/L858R-IN-7
EGFR T790M/L858R-IN-7 (Compound 72) is a novel pyrimidine compound that inhibits the EGFR T790M and L858R mutation with a high efficacy (93% inhibition rate at 0.05 μM). EGFR T790M/L858R-IN-7 functions by specifically binding to the kinase domain of EGFR, thereby inhibiting its phosphorylation activity.
For research use only. We do not sell to patients.
- CAS No.: 3032760-90-7
- Formula: C27H29N7O4
- Molecular Weight:515.56
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All EGFR Isoforms
More
Biological Activity
Chemical Information
-
CAS No. 3032760-90-7
-
Molecular Weight 515.56
-
Formula C27H29N7O4
-
SMILES
O=C(NC1=CC(NC2=NC=CC(N3C=CC4=CC=CN=C43)=N2)=C(OC)C=C1OC)/C=C/CN5CCOCC5
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)