5-Bromo-2-fluoropyridine
Based on 1 Customer Validation
5-Bromo-2-fluoropyridine is a halogenated pyridine precursor. 5-Bromo-2-fluoropyridine participates in Li-Br exchange to generate a pyridyl zinc halide for Negishi cross-coupling in the synthesis of nicotinic acetylcholine receptor agonist analogues.
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- Purity: 99.60%
- CAS No.: 766-11-0
- 화학식: C5H3BrFN
- 분자량:175.99
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보관:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
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Biological Activity
5-Bromo-2-fluoropyridine can be synthesized via a halogen exchange reaction between 5-bromo-2-chloropyridine and Potassium fluoride, or through the Schiemann reaction of 2-amino-5-bromopyridine[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 766-11-0
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Appearance Solid-Liquid Mixture
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분자량 175.99
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화학식 C5H3BrFN
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Color Colorless to light yellow
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SMILES
FC1=NC=C(Br)C=C1
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
용액&용해도
DMSO : ≥ 200 mg/mL (1136.43 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (271 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.6821 mL | 28.4107 mL | 56.8214 mL | 142.0535 mL |
| 5 mM | 1.1364 mL | 5.6821 mL | 11.3643 mL | 28.4107 mL | |
| 10 mM | 0.5682 mL | 2.8411 mL | 5.6821 mL | 14.2054 mL | |
| 15 mM | 0.3788 mL | 1.8940 mL | 3.7881 mL | 9.4702 mL | |
| 20 mM | 0.2841 mL | 1.4205 mL | 2.8411 mL | 7.1027 mL | |
| 25 mM | 0.2273 mL | 1.1364 mL | 2.2729 mL | 5.6821 mL | |
| 30 mM | 0.1894 mL | 0.9470 mL | 1.8940 mL | 4.7351 mL | |
| 40 mM | 0.1421 mL | 0.7103 mL | 1.4205 mL | 3.5513 mL | |
| 50 mM | 0.1136 mL | 0.5682 mL | 1.1364 mL | 2.8411 mL | |
| 60 mM | 0.0947 mL | 0.4735 mL | 0.9470 mL | 2.3676 mL | |
| 80 mM | 0.0710 mL | 0.3551 mL | 0.7103 mL | 1.7757 mL | |
| 100 mM | 0.0568 mL | 0.2841 mL | 0.5682 mL | 1.4205 mL |
5-Bromo-2-fluoropyridine Related Classifications
HY-32746 Related Classifications
Powered by Bioz
- 5-Bromo-2-fluoropyridine
- 766-11-0
- Biochemical Assay Reagents
- halogen exchange
- Li-Br exchange
- Schiemann reaction
- pyridyl zinc halide
- halogenated pyridine
- potassium fluoride
- Negishi cross-coupling
- 2-amino-5-bromopyridine
- 5-bromo-2-chloropyridine
- nicotinic acetylcholine receptor agonist analogues
- Inhibitor
- inhibitor
- inhibit