Pyrimidine-indole hybrid
Pyrimidine-indole hybrid is a compound that inhibits ciliogenesis and has the activity of antagonizing the Hedgehog signaling pathway by destabilizing microtubules. Pyrimidine-indole hybrid exerts its biological effects by inhibiting ciliogenesis and deconstructing the stable form of α-tubulin. Pyrimidine-indole hybrid has shown its unique mechanism of action in in vitro cell experiments and zebrafish embryo models, interfering with microtubule dynamics.
For research use only. We do not sell to patients.
- CAS No.: 441742-93-4
- Formula: C20H19N5S
- Molecular Weight:361.46
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Endogenous Metabolite Isoforms
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Biological Activity
Description
Chemical Information
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CAS No. 441742-93-4
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Molecular Weight 361.46
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Formula C20H19N5S
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SMILES
CC(NC1=C2C=CC=C1)=C2/C=N/NC3=C4C5=C(SC4=NC=N3)CCCC5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)