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Cat. No.: HY-118295

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Pyrimidine-indole hybrid

Pyrimidine-indole hybrid is a compound that inhibits ciliogenesis and has the activity of antagonizing the Hedgehog signaling pathway by destabilizing microtubules. Pyrimidine-indole hybrid exerts its biological effects by inhibiting ciliogenesis and deconstructing the stable form of α-tubulin. Pyrimidine-indole hybrid has shown its unique mechanism of action in in vitro cell experiments and zebrafish embryo models, interfering with microtubule dynamics.

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CAS No.: 441742-93-4
Formule: C₂₀H₁₉N₅S
Masse moléculaire:361.46

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (275 KB)

Pyrimidine-indole hybrid Chemical Structure

CAS No.: 441742-93-4

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Chemical Information

CAS No. 441742-93-4
Masse moléculaire 361.46
Formule C₂₀H₁₉N₅S
SMILES

CC(NC1=C2C=CC=C1)=C2/C=N/NC3=C4C5=C(SC4=NC=N3)CCCC5
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (275 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Hedgehog Antagonist Pyrimidine-Indole Hybrid Molecule Inhibits Ciliogenesis through Microtubule Destabilisation [Content Brief]

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1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Pyrimidine-indole hybrid

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Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

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Pyrimidine-indole hybrid Related Classifications

HY-118295 Related Classifications