Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
26 Results for "
rat liver homogenates
" in MedChemExpress (MCE) Product Catalog:
Products (26)
26 Results for "rat liver homogenates" in MCE Product Catalog:
1
1
Research Areas:
2,3-Oxidosqualene (Squalene oxide) is a sterol biosynthesis precursor intermediate.2,3-Oxidosqualene participates in cyclization pathways that form sterols and triterpenes, and contributes to introduction of their characteristic 3-hydroxyl group.2,3-Oxidosqualene forms metabolically from squalene in rat liver homogenates under sterol synthesis conditions.2,3-Oxidosqualene converts to sterols including cholesterol, lathosterol, and lanost-8-en-3β-ol in rat liver homogenates under anaerobic conditions .
1
1 Cited Publications
Synonyms: Ethanedioic acid diammonium monohydrate
Oxalic acid diammonium monohydrate shows antioxidant acyivity and suppresses lipid peroxidation.
Oxalic acid diammonium monohydrate is a pathogenicity factor for sclerotinia sclerotiorum, and suppresses the oxidative burst of the host plant. Oxalic acid diammonium monohydrate exerts acaricidal activity. Oxalic acid can be used for the researches of sclerotinia disease varroatosis and inflammatory diseases .
Category:
Target:
Research Areas:
CM398 is a highly selective, orally active Sigma-2 receptor ligand with a Ki value of 0.43 nM. CM398 ameliorates age-related macular degeneration. CM398 exerts analgesic effects on visceral pain, inflammatory pain and neuropathic pain. CM398 can be used in research related to age-related macular degeneration, neuropathic pain and inflammatory pain .
Cat. No.: HY-N11424
CAS No.: 17459-92-6
Category:
Target:
Cat. No.: HY-W041831
CAS No.: 1113-38-8
Synonyms: Ethanedioic acid ammonium
Target:
Research Areas:
Oxalic acid (Ethanedioic acid) ammonium is a dicarboxylic acid. Oxalic acid ammonium is widely found in various plants. Oxalic acid ammonium has antioxidant activity and can inhibit lipid peroxidation. Oxalic acid ammonium is a pathogenic factor of Sclerotinia sclerotiorum and can inhibit the oxidative burst of host plants. Oxalic acid ammonium has acaricidal activity. Oxalic acid ammonium can be used for related research on Sclerotinia sclerotiorum disease, Varroa mite disease and inflammatory diseases .
Cat. No.: HY-113422S
CAS No.: 2483831-29-2
Cat. No.: HY-114296S
Synonyms: Squalene oxide-d6
Cat. No.: HY-W150695
CAS No.: 575-36-0
Synonyms: N-(Naphthalen-1-yl)acetamide
1-Acetamidonaphthalene (N-(Naphthalen-1-yl)acetamide) is a degradation product of Digitoxigenin (HY-B2151). 1-Acetamidonaphthalene is weakly mutagenic to Salmonella typhimurium TA98 with metabolic activation. 1-Acetamidonaphthalene can be used for the research of bacterial infection .
Cat. No.: HY-W009934
CAS No.: 5005-36-7
Synonyms: α-Phenyl-2-pyridineacetonitrile
Target:
Research Areas:
2-Phenyl-2-(2-pyridyl)acetonitrile is the major metabolite of SC 15396 metabolized by the supernatant fraction of rat liver homogenate. SC 15396 is an antigastrin that inhibits gastric secretion .
Cat. No.: HY-W009934R
CAS No.: 5005-36-7
Synonyms: α-Phenyl-2-pyridineacetonitrile (Standard)
Target:
Research Areas:
2-Phenyl-2-(2-pyridyl)acetonitrile (Standard) is the analytical standard of 2-Phenyl-2-(2-pyridyl)acetonitrile. This product is intended for research and analytical applications. 2-Phenyl-2-(2-pyridyl)acetonitrile is the major metabolite of SC 15396 metabolized by the supernatant fraction of rat liver homogenate. SC 15396 is an antigastrin that inhibits gastric secretion[1].
Cat. No.: HY-105572
CAS No.: 85921-53-5
Synonyms: MC-838 calcium
Research Areas:
Moveltipril calcium (MC-838 calcium) is an orally active angiotensin converting enzyme (ACE) inhibitor with antihypertensive activity. Moveltipril calcium binds via a stable thioester bond and exhibits relative resistance to enzymatic hydrolysis in rat liver homogenate. Moveltipril calcium effectively inhibits ACE extracted from rabbit lung in a concentration-dependent manner. Moveltipril calcium is able to highly specifically inhibit the contractile response to angiotensin-I (AI) in free rat aortic rings and guinea pig ileum preparations, while enhancing the contractile response to calcitonin .
Cat. No.: HY-182251
CAS No.: 70475-39-7
Synonyms: GSOAN
Target:
Research Areas:
Glutathione sulfinanilide (GSOAN) is a derivative of Nitrosobenzene (HY-121641). Glutathione sulfinanilide can be generated by the reaction of Nitrosobenzene with GSH. Glutathione sulfinanilide is degradable in rat liver homogenate .
Cat. No.: HY-19109
CAS No.: 107813-63-8
Target:
Research Areas:
RG-7152 is a tetrazolyl-substituted leukotriene D4 receptor antagonist that can induce peroxisomal β-oxidation and peroxisome bifunctional enzymes (PBEs) in hepatocytes in various animal models. It has been shown to significantly increase PBE levels and β-oxidation activity in rat and mouse liver homogenates, while smaller effects were observed in guinea pigs and monkeys and no effect in dogs. In vitro studies have also shown that it can induce PBEs comparable to clofibric acid, indicating its potential as a peroxisome proliferator .
Cat. No.: HY-113422S1
Cat. No.: HY-171478
CAS No.: 33406-68-7
Target:
Research Areas:
SQ 11,447 is a methylurea analogue that demonstrates remarkable resistance to hydrolysis in both in vitro (rat, dog, and human liver homogenates) and in vivo (rat) experimental models.
Cat. No.: HY-123273
CAS No.: 17159-42-1
Target:
Research Areas:
Metyrapol is a steroid 11β-hydroxylase inhibitor. Metyrapol blocks the conversion of deoxycorticosterone to corticosterone in rat adrenal homogenates. Metyrapol can be used in the study of metabolic diseases .
Cat. No.: HY-183434
CAS No.: 21738-41-0
Desoxymansil is an anti-schistosomal agent. In mice, rabbits, dogs and monkeys, Desoxymansil undergoes oxidative metabolism via its isopropylaminomethyl side chain to produce a carboxylic acid metabolite, while this metabolic pathway is absent in rats. In rats, Desoxymansil undergoes α-carbon oxidation of the side chain to form an unstable aminomethanol that decomposes; the intermediate product is reduced to an alcohol metabolite, which is excreted in bile in the form of glucuronide. Desoxymansil can be used for the study of schistosomiasis .
Cat. No.: HY-W725454
CAS No.: 118-57-0
Target:
Research Areas:
Acetaminosalol, a merged ester NSAID–APAP hybrid, is a metabolite of Benorylate (HY-107795) and a prodrug of Acetaminophen (HY-66005) and Aalicylic acid (HY-B0167). Acetaminosalol can be used for the research of acute rheumatism .
- 1
- 2
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
