2. GPCR/G Protein Neuronal Signaling Immunology/Inflammation
  3. Histamine Receptor
  4. Setastine

Setastine  (Synonyms: EGIS-2062 free acid; EGYT-2062 free acid)

Cat. No.: HY-119832 Purity: 99.21%
COA
SDS
Handling Instructions Technical Support

Setastine (EGIS-2062 (free acid); EGYT-2062 (free acid) is an orally effective, non-sedative and long acting anti-allergic agent. Setastine possesses potent histamine Hi-receptor blocking properties and can be used for allergies and rhinitis research[1]<.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

Setastine

Setastine 화학구조

CAS No. : 64294-95-7

사이즈 가격 재고 수량
Liquid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 해외재고보유
Solution
10 mM * 1 mL in DMSO 해외재고보유
Liquid
5 mg 해외재고보유
10 mg 해외재고보유
25 mg 해외재고보유
50 mg 해외재고보유
100 mg 해외재고보유
200 mg   견적 받기  
500 mg   견적 받기  

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 1 Customer Validation

Other Forms of Setastine:

Setastine Related Antibodies

Top Publications Citing Use of Products

View All Histamine Receptor Isoform Specific Products:

View All Isoforms
H1 Receptor H2 Receptor H3 Receptor H4 Receptor Histamine Receptor

  • Biological Activity

  • 순도&문서

  • References

  • 고객리뷰

제품 설명

Setastine (EGIS-2062 (free acid); EGYT-2062 (free acid) is an orally effective, non-sedative and long acting anti-allergic agent. Setastine possesses potent histamine Hi-receptor blocking properties and can be used for allergies and rhinitis research[1]<.

IC50 & Target

IC50:Histamine Hi-receptor[1]
분자량

357.92

화학식

C22H28ClNO
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

CC(C1=CC=C(C=C1)Cl)(OCCN2CCCCCC2)C3=CC=CC=C3
선적

Room temperature in continental US; may vary elsewhere.
보관
Pure form -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
용액&용해도
In Vitro: 

DMSO : ≥ 125 mg/mL (349.24 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.7939 mL 13.9696 mL 27.9392 mL
5 mM 0.5588 mL 2.7939 mL 5.5878 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • 몰농도 계산기

  • 농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
순도&문서
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.7939 mL 13.9696 mL 27.9392 mL 69.8480 mL
5 mM 0.5588 mL 2.7939 mL 5.5878 mL 13.9696 mL
10 mM 0.2794 mL 1.3970 mL 2.7939 mL 6.9848 mL
15 mM 0.1863 mL 0.9313 mL 1.8626 mL 4.6565 mL
20 mM 0.1397 mL 0.6985 mL 1.3970 mL 3.4924 mL
25 mM 0.1118 mL 0.5588 mL 1.1176 mL 2.7939 mL
30 mM 0.0931 mL 0.4657 mL 0.9313 mL 2.3283 mL
40 mM 0.0698 mL 0.3492 mL 0.6985 mL 1.7462 mL
50 mM 0.0559 mL 0.2794 mL 0.5588 mL 1.3970 mL
60 mM 0.0466 mL 0.2328 mL 0.4657 mL 1.1641 mL
80 mM 0.0349 mL 0.1746 mL 0.3492 mL 0.8731 mL
100 mM 0.0279 mL 0.1397 mL 0.2794 mL 0.6985 mL
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Setastine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Setastine64294-95-7EGIS-2062EGYT-2062EGIS2062EGIS 2062EGYT2062EGYT 2062Histamine Receptorallergic rhinoconjunctivitisrhinitis,antihistamine agent?Inhibitorinhibitorinhibit

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상품명:
Setastine
Cat. No.:
HY-119832
수량:
MCE Japan Authorized Agent:

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SAFETY DATA SHEET (SDS)

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