2. Anti-infection
  3. Parasite
  4. T.cruzi-IN-4

T.cruzi-IN-4 (Compound 21) is an anti-parasitic agent. T.cruzi-IN-4 inhibits the trypomastigote and amastigote form of Trypanosoma cruzi with IC50 of 0.033 μM (120 h), T.cruzi-IN-4 inhibits the promastigote and amastigote form of Leishmania infantum with IC50 of 28.74 and 61.82 μM. T.cruzi-IN-4 inhibits Leishmania amazonensis promastigote form with IC50 of 18.38 μM.

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T.cruzi-IN-4

T.cruzi-IN-4 Estructura química

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T.cruzi-IN-4 Related Antibodies

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Amebae Coccidia Leishmania Mite Plasmodium Toxoplasma Trypanosoma Schistosome

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Descripciòn

T.cruzi-IN-4 (Compound 21) is an anti-parasitic agent. T.cruzi-IN-4 inhibits the trypomastigote and amastigote form of Trypanosoma cruzi with IC50 of 0.033 μM (120 h), T.cruzi-IN-4 inhibits the promastigote and amastigote form of Leishmania infantum with IC50 of 28.74 and 61.82 μM. T.cruzi-IN-4 inhibits Leishmania amazonensis promastigote form with IC50 of 18.38 μM[1].

Cellular Effect
Cell Line Type Value Description References
L929 CC50
256.6 μM
Compound: 21
Cytotoxicity against mouse L929 cells assessed as inhibition of cell viability measured after 120 hrs
Cytotoxicity against mouse L929 cells assessed as inhibition of cell viability measured after 120 hrs
[PMID: 38964519]
RAW264.7 CC50
25.73 μM
Compound: 21
Cytotoxicity against mouse RAW264.7 cells measured after 48 hrs
Cytotoxicity against mouse RAW264.7 cells measured after 48 hrs
[PMID: 38964519]
Peso molecular

299.24

Fòrmula

C13H9N5O4
SMILES

O=C(C1=NC2=CC=CC=C2N1)N/N=C/C3=CC=C([N+]([O-])=O)O3
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.
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Referencias
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T.cruzi-IN-4 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

T.cruzi-IN-4ParasiteTrypanosoma cruziLeishmania infantumLeishmania amazonensisInhibitorinhibitorinhibit

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Nombre del producto:
T.cruzi-IN-4
Cat. No.:
HY-159097
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