2. Anti-infection
  3. Reverse Transcriptase HIV
  4. Tenofovir diphosphate

Tenofovir diphosphate is an antiretroviral agent. Tenofovir diphosphate is an inhibitor of HIV reverse transcriptase DNA (Ki = 1.55 μM) and RNA (Ki = 0.022 μM). Tenofovir diphosphate can be used for the research of AIDS.

It is advisable to consider the salt form (Tenofovir diphosphate disodium) that retains the same biological activity.

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Tenofovir diphosphate

Tenofovir diphosphate Estructura química

No. CAS : 166403-66-3

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Other Forms of Tenofovir diphosphate:

Tenofovir diphosphate Related Antibodies

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Descripciòn

Tenofovir diphosphate is an antiretroviral agent. Tenofovir diphosphate is an inhibitor of HIV reverse transcriptase DNA (Ki = 1.55 μM) and RNA (Ki = 0.022 μM). Tenofovir diphosphate can be used for the research of AIDS[1].

IC50 & Target

DNA polymerases; HIV-1 reverse transcriptase[1]
In Vitro

Tenofovir diphosphate acts as an inhibitor of DNA pol. Tenofovir-diphosphate is a weak inhibitor of DNA polymerases (pol) α, δ, and , with values for the Ki for PMPApp (PMPAppKi) relative to the Km for dATP (dATPKm) of 10.2, 10.2, and 15.6, respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Tenofovir diphosphate Related Antibodies
Peso molecular

447.17

Fòrmula

C9H16N5O10P3
No. CAS
SMILES

C[C@@H](OC[P](O[P](O[P](O)(O)=O)(O)=O)(O)=O)CN1C2=NC=NC(N)=C2N=C1
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
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Tenofovir diphosphate Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tenofovir diphosphate166403-66-3TFV-DPReverse TranscriptaseHIVHuman immunodeficiency virusDNApolymerasessubstrateHIV-1reversetranscriptaseInhibitorinhibitorinhibit

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Nombre del producto:
Tenofovir diphosphate
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HY-136548
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