1. Anti-infection
  2. Reverse Transcriptase
  3. Tenofovir diphosphate triethylamine

Tenofovir diphosphate triethylamine (Synonyms: TFV-DP triethylamine)

Cat. No.: HY-136548A Purity: 94.93%
Handling Instructions

Tenofovir diphosphate triethylamine (TFV-DP triethylamine) is a competitive DNA polymerases inhibitor (with respect to dATP) and a substrate of HIV type 1 (HIV-1) reverse transcriptase (RT).

For research use only. We do not sell to patients.

Tenofovir diphosphate triethylamine Chemical Structure

Tenofovir diphosphate triethylamine Chemical Structure

CAS No. : 2122333-63-3

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Description

Tenofovir diphosphate triethylamine (TFV-DP triethylamine) is a competitive DNA polymerases inhibitor (with respect to dATP) and a substrate of HIV type 1 (HIV-1) reverse transcriptase (RT)[1].

In Vitro

Tenofovir diphosphate acts as an inhibitor of DNA pol. Tenofovir-diphosphate is a weak inhibitor of DNA polymerases (pol) α, δ, and ɛ, with values for the Ki for PMPApp (PMPAppKi) relative to the Km for dATP (dATPKm) of 10.2, 10.2, and 15.6, respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

548.36

Formula

C₁₅H₃₁N₆O₁₀P₃

CAS No.

2122333-63-3

SMILES

C[[email protected]@H](OC[P](O[P](O[P](O)(O)=O)(O)=O)(O)=O)CN1C2=NC=NC(N)=C2N=C1.CCN(CC)CC

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, protect from light, stored under argon

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under argon)

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Keywords:

Tenofovir diphosphateTFV-DPReverse TranscriptaseDNApolymerasessubstrateHIVHIV-1reversetranscriptaseInhibitorinhibitorinhibit

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Tenofovir diphosphate triethylamine
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